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Phylogenetic placement refers to a family of tools and methods to analyze, visualize, and interpret the tsunami of metagenomic sequencing data generated by high-throughput sequencing. Compared to alternative (e. g., similarity-based)…

Populations and Evolution · Quantitative Biology 2025-01-09 Lucas Czech , Alexandros Stamatakis , Micah Dunthorn , Pierre Barbera

Phage therapy is an alternative treatment method for bacterial infections. It has shown particular promise in reducing bacterial load while preventing antibiotic resistance. Here, we develop a mathematical model of a bacterial infection…

Populations and Evolution · Quantitative Biology 2025-12-23 Rohan Shirur , Bryce Morsky

In ecology it has become common to apply DNA barcoding to biological samples leading to datasets containing a large number of nucleotide sequences. The focus is then on inferring the taxonomic placement of each of these sequences by…

Applications · Statistics 2022-01-25 Alessandro Zito , Tommaso Rigon , David B. Dunson

Understanding the dynamics of genome rearrangements is a major issue of phylogenetics. Phylogenetics is the study of species evolution. A major goal of the field is to establish evolutionary relationships within groups of species, in order…

Data Structures and Algorithms · Computer Science 2014-10-22 Antoine Thomas

Statistical physics can describe the behavior of microbial populations consisting of many heterogeneous individuals. A direct consequence is the existence of phase transitions, where the behavior of a population changes discontinuously upon…

Populations and Evolution · Quantitative Biology 2026-04-20 Kaan Öcal , Syrine Ghrabli , Michael P. H. Stumpf

Although the role of lateral gene transfer is well recognized in the evolution of bacteria, it is generally assumed that it has had less influence among eukaryotes. To explore this hypothesis we compare the dynamics of genome evolution in…

Populations and Evolution · Quantitative Biology 2015-07-16 Gergely J. Szöllősi , Adrián Arellano Davín , Eric Tannier , Vincent Daubin , Bastien Boussau

Multivariate clustering in astrophysics is a recent development justified by the bigger and bigger surveys of the sky. The phylogenetic approach is probably the most unexpected technique that has appeared for the unsupervised classification…

Instrumentation and Methods for Astrophysics · Physics 2017-03-02 Didier Fraix-Burnet

We present a method for hierarchic categorization and taxonomy evolution description. We focus on the structure of epistemic communities (ECs), or groups of agents sharing common knowledge concerns. Introducing a formal framework based on…

Adaptation and Self-Organizing Systems · Physics 2016-09-08 Camille Roth , Paul Bourgine

Phylogenetic approaches to classification have been heavily developed in biology by bioinformaticians. But these techniques have applications in other fields, in particular in linguistics. Their main characteristics is to search for…

Instrumentation and Methods for Astrophysics · Physics 2016-06-07 Didier Fraix-Burnet

It is possible to borrow from a topic of biology called phylogenetic systematics, concepts and tools for a logical and objective classification of galaxies. It is based on observable properties of objects - characters - either qualitative…

Astrophysics · Physics 2009-11-07 Didier Fraix-Burnet , Philippe Choler , Emmanuel J. P. Douzery

Phylogenetics is a widely used concept in evolutionary biology. It is the reconstruction of evolutionary history by building trees that represent branching patterns and sequences. These trees represent shared history, and it is our…

Astrophysics of Galaxies · Physics 2018-08-22 P. Jofre , P. Das

Plants are fundamentally important to life. Key research areas in plant science include plant species identification, weed classification using hyper spectral images, monitoring plant health and tracing leaf growth, and the semantic…

Computer Vision and Pattern Recognition · Computer Science 2020-09-15 K. K. Thyagharajan , I. Kiruba Raji

The morphological classification of galaxies provides vital physical information about the orbital motions of stars in galaxies, and correlates in interesting ways with star formation history, and other physical properties. Galaxy…

Astrophysics of Galaxies · Physics 2025-02-14 Karen Masters

Preliminary diagnosis of fungal infections can rely on microscopic examination. However, in many cases, it does not allow unambiguous identification of the species by microbiologist due to their visual similarity. Therefore, it is usually…

Computer Vision and Pattern Recognition · Computer Science 2020-09-09 Bartosz Zieliński , Agnieszka Sroka-Oleksiak , Dawid Rymarczyk , Adam Piekarczyk , Monika Brzychczy-Włoch

Gerbes are locally connected presheaves of groupoids. They are classified up to local weak equivalence by path components in a 2-cocycle category taking values in all sheaves of groups, their isomorphisms and homotopies. If F is a full…

Algebraic Topology · Mathematics 2007-05-23 J. F. Jardine

Filamentous phage, such as fd used in this study, are thread-shaped bacterial viruses. Their outer coat is a tube formed by thousands equal copies of the major coat protein pVIII. We constructed libraries of random peptides fused to all…

Understanding how genes interact and relate to each other is a fundamental question in biology. However, current practices for describing these relationships, such as drawing diagrams or graphs in a somewhat arbitrary manner, limit our…

Other Quantitative Biology · Quantitative Biology 2023-11-16 Yanying Wu

Diagnosis of fungal infections can rely on microscopic examination, however, in many cases, it does not allow unambiguous identification of the species due to their visual similarity. Therefore, it is usually necessary to use additional…

Computer Vision and Pattern Recognition · Computer Science 2020-10-14 Bartosz Zieliński , Agnieszka Sroka-Oleksiak , Dawid Rymarczyk , Adam Piekarczyk , Monika Brzychczy-Włoch

Molecular phylogenetic and phylogeographic reconstructions generally assume time-homogeneous substitution processes. Motivated by computational convenience, this assumption sacrifices biological realism and offers little opportunity to…

Populations and Evolution · Quantitative Biology 2013-09-13 Filip Bielejec , Philippe Lemey , Guy Baele , Andrew Rambaut , Marc A Suchard

Phylogenetic inference, grounded in molecular evolution models, is essential for understanding the evolutionary relationships in biological data. Accounting for the uncertainty of phylogenetic tree variables, which include tree topologies…

Machine Learning · Computer Science 2023-12-04 Takahiro Mimori , Michiaki Hamada