English
Related papers

Related papers: A free energy principle for generic quantum system…

200 papers

This paper presents a model of consciousness that follows directly from the free-energy principle (FEP). We first rehearse the classical and quantum formulations of the FEP. In particular, we consider the inner screen hypothesis that…

Neurons and Cognition · Quantitative Biology 2024-01-03 Maxwell J. D. Ramstead , Mahault Albarracin , Alex Kiefer , Brennan Klein , Chris Fields , Karl Friston , Adam Safron

The Free Energy Principle (FEP) describes (biological) agents as minimising a variational Free Energy (FE) with respect to a generative model of their environment. Active Inference (AIF) is a corollary of the FEP that describes how agents…

Machine Learning · Statistics 2025-01-03 Thijs van de Laar , Magnus Koudahl , Bert de Vries

This thesis focuses on three fundamental aspects of biological systems; namely, entropy production, Bayesian mechanics, and the free-energy principle. The contributions are threefold: 1) We compute the entropy production for a greater class…

Mathematical Physics · Physics 2024-10-16 Lancelot Da Costa

Physical AI agents, such as robots and other embodied systems operating under tight and fluctuating resource constraints, remain far less capable than biological agents in open-ended real-world environments. This paper argues that Active…

Machine Learning · Statistics 2026-03-24 Bert de Vries

This study examines a new formulation of non-equilibrium thermodynamics, which gives a conditional derivation of the ``maximum entropy production'' (MEP) principle for flow and/or chemical reaction systems at steady state. The analysis uses…

Populations and Evolution · Quantitative Biology 2009-08-25 Robert K. Niven

Free energy perturbation (FEP) is frequently used to evaluate the free energy change of a biological process, e.g. the drug binding free energy or the ligand solvation free energy. Due to the sampling inefficiency, FEP is often employed…

Chemical Physics · Physics 2017-01-31 Ying-Chih Chiang , Frank Otto

The Targeted Free Energy Perturbation (TFEP) method aims to overcome the time-consuming and computer-intensive stratification process of standard methods for estimating the free energy difference between two states. To achieve this, TFEP…

Chemical Physics · Physics 2023-02-24 Soo Jung Lee , Amr H. Mahmoud , Markus A. Lill

In this paper, a simple case of Bayesian mechanics under the free energy principle is formulated in axiomatic terms. We argue that any dynamical system with constraints on its dynamics necessarily looks as though it is performing inference…

Mathematical Physics · Physics 2022-04-27 Dalton A R Sakthivadivel

We develop a quantum version of the probability estimation framework [arXiv:1709.06159] for randomness generation with quantum side information. We show that most of the properties of probability estimation hold for quantum probability…

Quantum Physics · Physics 2023-02-06 Emanuel Knill , Yanbao Zhang , Honghao Fu

Free energy perturbation (FEP) was proposed by Zwanzig more than six decades ago as a method to estimate free energy differences, and has since inspired a huge body of related methods that use it as an integral building block. Being an…

Organisms are nonequilibrium, stationary systems self-organized via spontaneous symmetry breaking and undergoing metabolic cycles with broken detailed balance in the environment. The thermodynamic free-energy principle describes an…

Neurons and Cognition · Quantitative Biology 2022-11-24 Chang Sub Kim

We develop a novel data-driven approach to the inverse problem of classical statistical mechanics: given experimental data on the collective motion of a classical many-body system, how does one characterise the free energy landscape of that…

Statistical Mechanics · Physics 2022-03-01 Peter Yatsyshin , Serafim Kalliadasis , Andrew B. Duncan

The free energy functional has recently been proposed as a variational principle for bounded rational decision-making, since it instantiates a natural trade-off between utility gains and information processing costs that can be…

Machine Learning · Statistics 2012-05-18 Pedro A. Ortega , Daniel A. Braun

We address the problem of computing approximate marginals in Gaussian probabilistic models by using mean field and fractional Bethe approximations. We define the Gaussian fractional Bethe free energy in terms of the moment parameters of the…

Machine Learning · Computer Science 2014-01-17 Botond Cseke , Tom Heskes

In QM/MM indirect free energy simulation, QM/MM corrections can be obtained from integration of partial derivatives of alchemical Hamiltonians or from perturbation-based estimators including free energy perturbation (FEP) and acceptance…

Chemical Physics · Physics 2018-10-05 Xiaohui Wang , Zhaoxi Sun

In a recent technical critique of the free energy principle (FEP) due to Aguilera-Millidge-Tschantz-Buckley, it is argued that there are a number of instances where the FEP$\unicode{x2014}$as conventionally written, in terms of densities…

Statistical Mechanics · Physics 2022-06-02 Dalton A R Sakthivadivel

Bayesian mechanics provides a framework that addresses dynamical systems that can be conceptualised as Bayesian inference. However, elucidating the requisite generative models is essential for empirical applications to realistic…

Neurons and Cognition · Quantitative Biology 2024-12-02 Takuya Isomura

Systematic inaccuracy is inherent in any computational estimate of a non-linear average, due to the availability of only a finite number of data values, N. Free energy differences (DF) between two states or systems are critically important…

Computational Physics · Physics 2009-11-07 Daniel M. Zuckerman , Thomas B. Woolf

The free energy principle, and its corollary active inference, constitute a bio-inspired theory that assumes biological agents act to remain in a restricted set of preferred states of the world, i.e., they minimize their free energy. Under…

Machine Learning · Computer Science 2022-07-15 Pietro Mazzaglia , Tim Verbelen , Ozan Çatal , Bart Dhoedt

We revisit the proof of the limiting free energy of the continuous random energy model (CREM) using the Hamilton--Jacobi approach for mean-field disordered systems. To achieve this, we introduce an enriched model that interpolates between…

Probability · Mathematics 2025-08-26 Alexander Alban , Fu-Hsuan Ho , Justin Ko