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Privacy-preserving genomic data sharing is prominent to increase the pace of genomic research, and hence to pave the way towards personalized genomic medicine. In this paper, we introduce ($\epsilon , T$)-dependent local differential…

Cryptography and Security · Computer Science 2021-02-16 Emre Yilmaz , Tianxi Ji , Erman Ayday , Pan Li

Motivation: Researchers need a rich trove of genomic datasets that they can leverage to gain a better understanding of the genetic basis of the human genome and identify associations between phenotypes and specific parts of DNA. However,…

Cryptography and Security · Computer Science 2021-06-10 Nour Almadhoun Alserr , Gulce Kale , Onur Mutlu , Oznur Tastan , Erman Ayday

Differential privacy (DP) has become a rigorous central concept for privacy protection in the past decade. We use Gaussian differential privacy (GDP) in gauging the level of privacy protection for releasing statistical summaries from data.…

Methodology · Statistics 2025-04-01 Minwoo Kim , Jonghyeok Lee , Seung Woo Kwak , Sungkyu Jung

When querying databases containing sensitive information, the privacy of individuals stored in the database has to be guaranteed. Such guarantees are provided by differentially private mechanisms which add controlled noise to the query…

Databases · Computer Science 2020-08-26 William Lee Croft , Jörg-Rüdiger Sack , Wei Shi

Assessment of disclosure risk is of paramount importance in the research and applications of data privacy techniques. The concept of differential privacy (DP) formalizes privacy in probabilistic terms and provides a robust concept for…

Statistics Theory · Mathematics 2020-07-01 Fang Liu

There is an increasing demand to make data "open" to third parties, as data sharing has great benefits in data-driven decision making. However, with a wide variety of sensitive data collected, protecting privacy of individuals, communities…

Cryptography and Security · Computer Science 2017-07-19 David B. Smith , Kanchana Thilakarathna , Mohamed Ali Kaafar

Differentially private data generation techniques have become a promising solution to the data privacy challenge -- it enables sharing of data while complying with rigorous privacy guarantees, which is essential for scientific progress in…

Cryptography and Security · Computer Science 2022-11-09 Dingfan Chen , Raouf Kerkouche , Mario Fritz

Genome sequencing technology has advanced at a rapid pace and it is now possible to generate highly-detailed genotypes inexpensively. The collection and analysis of such data has the potential to support various applications, including…

Cryptography and Security · Computer Science 2015-06-18 Muhammad Naveed , Erman Ayday , Ellen W. Clayton , Jacques Fellay , Carl A. Gunter , Jean-Pierre Hubaux , Bradley A. Malin , XiaoFeng Wang

Popular approaches to differential privacy, such as the Laplace and exponential mechanisms, calibrate randomised smoothing through global sensitivity of the target non-private function. Bounding such sensitivity is often a prohibitively…

Machine Learning · Computer Science 2017-06-12 Benjamin I. P. Rubinstein , Francesco Aldà

In an MPC-protected distributed computation, although the use of MPC assures data privacy during computation, sensitive information may still be inferred by curious MPC participants from the computation output. This can be observed, for…

Cryptography and Security · Computer Science 2025-03-11 Ivan Tjuawinata , Jiabo Wang , Mengmeng Yang , Shanxiang Lyu , Huaxiong Wang , Kwok-Yan Lam

The paper aims to give an overview of various approaches to statistical disclosure control based on random noise that are currently being discussed for official population statistics and censuses. A particular focus is on a stringent…

Methodology · Statistics 2020-12-18 Fabian Bach

The projected increase of genotyping in the clinic and the rise of large genomic databases has led to the possibility of using patient medical data to perform genomewide association studies (GWAS) on a larger scale and at a lower cost than…

Quantitative Methods · Quantitative Biology 2016-04-18 Sean Simmons , Cenk Sahinalp , Bonnie Berger

In recent years, differential privacy has been adopted by tech-companies and governmental agencies as the standard for measuring privacy in algorithms. In this article, we study differential privacy in Bayesian posterior sampling settings.…

Statistics Theory · Mathematics 2026-02-13 Shenggang Hu , Louis Aslett , Hongsheng Dai , Murray Pollock , Gareth O. Roberts

Differential privacy (DP) is obtained by randomizing a data analysis algorithm, which necessarily introduces a tradeoff between its utility and privacy. Many DP mechanisms are built upon one of two underlying tools: Laplace and Gaussian…

Machine Learning · Computer Science 2026-04-03 Roy Rinberg , Ilia Shumailov , Vikrant Singhal , Rachel Cummings , Nicolas Papernot

Traditional statistical methods for confidentiality protection of statistical databases do not scale well to deal with GWAS (genome-wide association studies) databases especially in terms of guarantees regarding protection from linkage to…

Methodology · Statistics 2012-05-04 Caroline Uhler , Aleksandra B. Slavkovic , Stephen E. Fienberg

The objective of differential privacy (DP) is to protect privacy by producing an output distribution that is indistinguishable between any two neighboring databases. However, traditional differentially private mechanisms tend to produce…

Cryptography and Security · Computer Science 2023-11-07 Kai Zhang , Yanjun Zhang , Ruoxi Sun , Pei-Wei Tsai , Muneeb Ul Hassan , Xin Yuan , Minhui Xue , Jinjun Chen

Metaverse-enabled digital healthcare systems are expected to exploit an unprecedented amount of personal health data, while ensuring that sensitive or private information of individuals are not disclosed. Machine learning and artificial…

Cryptography and Security · Computer Science 2023-08-22 Mehdi Letafati , Safa Otoum

Generative Adversarial Network (GAN) and its variants have recently attracted intensive research interests due to their elegant theoretical foundation and excellent empirical performance as generative models. These tools provide a promising…

Machine Learning · Computer Science 2018-02-20 Liyang Xie , Kaixiang Lin , Shu Wang , Fei Wang , Jiayu Zhou

Differential Privacy protects individuals' data when statistical queries are published from aggregated databases: applying "obfuscating" mechanisms to the query results makes the released information less specific but, unavoidably, also…

Cryptography and Security · Computer Science 2021-07-27 Natasha Fernandes , Annabelle McIver , Carroll Morgan

We propose the first method that realizes the Laplace mechanism exactly (i.e., a Laplace noise is added to the data) that requires only a finite amount of communication (whereas the original Laplace mechanism requires the transmission of a…

Cryptography and Security · Computer Science 2023-09-14 Ali Moradi Shahmiri , Chih Wei Ling , Cheuk Ting Li
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