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Stabilizing proteins is a foundational step in protein engineering. However, the evolutionary pressure of all extant proteins makes identifying the scarce number of mutations that will improve thermodynamic stability challenging. Deep…

Biomolecules · Quantitative Biology 2023-11-01 Jeffrey Ouyang-Zhang , Daniel J. Diaz , Adam R. Klivans , Philipp Krähenbühl

Mutation testing is a well-established technique for assessing a test suite's quality by injecting artificial faults into production code. In recent years, mutation testing has been extended to machine learning (ML) systems, and deep…

Software Engineering · Computer Science 2021-03-03 Annibale Panichella , Cynthia C. S. Liem

We propose Class Based Thresholding (CBT) to reduce the computational cost of early exit semantic segmentation models while preserving the mean intersection over union (mIoU) performance. A key idea of CBT is to exploit the…

Computer Vision and Pattern Recognition · Computer Science 2022-10-28 Alperen Görmez , Erdem Koyuncu

Abstaining classifiers have been widely used in cost-sensitive applications to avoid ambiguous classification and reduce the cost of misclassification. Previous abstaining classification models rely on cost information, such as a cost…

Machine Learning · Computer Science 2019-05-20 Hongjiao Guan

Non-parametric two-sample tests based on energy distance or maximum mean discrepancy are widely used statistical tests for comparing multivariate data from two populations. While these tests enjoy desirable statistical properties, their…

Computation · Statistics 2024-06-11 Elias Chaibub Neto

Feature selection is an important preprocessing step in machine learning and data mining. In real-world applications, costs, including money, time and other resources, are required to acquire the features. In some cases, there is a test…

Artificial Intelligence · Computer Science 2013-05-22 Fan Min , Qinghua Hu , William Zhu

Neutral landscapes and mutational robustness are believed to be important enablers of evolvability in biology. We apply these concepts to software, defining mutational robustness to be the fraction of random mutations that leave a program's…

Software Engineering · Computer Science 2013-06-28 Eric Schulte , Zachary P. Fry , Ethan Fast , Westley Weimer , Stephanie Forrest

Recently, there emerged revived interests of designing automatic programs (e.g., using genetic/evolutionary algorithms) to optimize the structure of Convolutional Neural Networks (CNNs) for a specific task. The challenge in designing such…

Neural and Evolutionary Computing · Computer Science 2018-06-05 Zhe Li , Xuehan Xiong , Zhou Ren , Ning Zhang , Xiaoyu Wang , Tianbao Yang

The stochastic nature of iterative optimization heuristics leads to inherently noisy performance measurements. Since these measurements are often gathered once and then used repeatedly, the number of collected samples will have a…

Neural and Evolutionary Computing · Computer Science 2022-04-25 Diederick Vermetten , Hao Wang , Manuel López-Ibañez , Carola Doerr , Thomas Bäck

The problem of selecting an appropriate number of features in supervised learning problems is investigated in this paper. Starting with common methods in machine learning, we treat the feature selection task as a quadratic unconstrained…

Quantum Physics · Physics 2023-06-21 Gerhard Hellstern , Vanessa Dehn , Martin Zaefferer

Performance regressions have a tremendous impact on the quality of software. One way to catch regressions before they reach production is executing performance tests before deployment, e.g., using microbenchmarks, which measure performance…

Software Engineering · Computer Science 2025-10-22 Nils Japke , Martin Grambow , Christoph Laaber , David Bermbach

Rapid adoptions of Deep Learning (DL) in a broad range of fields led to the development of specialised testing techniques for DL systems, including DL mutation testing. However, existing post-training DL mutation techniques often generate…

Software Engineering · Computer Science 2025-01-23 Jinhan Kim , Nargiz Humbatova , Gunel Jahangirova , Shin Yoo , Paolo Tonella

With the increasing demand for deep learning models on mobile devices, splitting neural network computation between the device and a more powerful edge server has become an attractive solution. However, existing split computing approaches…

Machine Learning · Computer Science 2025-01-06 Yoshitomo Matsubara , Ruihan Yang , Marco Levorato , Stephan Mandt

Malware detection is an ever-present challenge for all organizational gatekeepers, who must maintain high detection rates while minimizing interruptions to the organization's workflow. To improve detection rates, organizations often deploy…

Cryptography and Security · Computer Science 2020-05-21 Yoni Birman , Shaked Hindi , Gilad Katz , Asaf Shabtai

Numerous code changes are made by developers in their daily work, and a superior representation of code changes is desired for effective code change analysis. Recently, Hoang et al. proposed CC2Vec, a neural network-based approach that…

Software Engineering · Computer Science 2023-09-28 Xin Zhou , Bowen Xu , DongGyun Han , Zhou Yang , Junda He , David Lo

Active learning, a powerful paradigm in machine learning, aims at reducing labeling costs by selecting the most informative samples from an unlabeled dataset. However, the traditional active learning process often demands extensive…

Machine Learning · Computer Science 2024-01-17 Gábor Németh , Tamás Matuszka

On-board embedded software developed for spaceflight systems (space software) must adhere to stringent software quality assurance procedures. For example, verification and validation activities are typically performed and assessed by third…

Software Engineering · Computer Science 2021-08-24 Oscar Cornejo , Fabrizio Pastore , Lionel Briand

Programming courses can be challenging for first year university students, especially for those without prior coding experience. Students initially struggle with code syntax, but as more advanced topics are introduced across a semester, the…

Programming Languages · Computer Science 2024-04-10 Valdemar Švábenský , Maciej Pankiewicz , Jiayi Zhang , Elizabeth B. Cloude , Ryan S. Baker , Eric Fouh

Quantum computing has been on the rise in recent years, evidenced by a surge in publications on quantum software engineering and testing. Progress in quantum hardware has also been notable, with the introduction of impressive systems like…

Software Engineering · Computer Science 2024-10-03 Sinhué García Gil , Luis Llana Díaz , José Ignacio Requeno Jarabo

Simulation is a fundamental research tool in the computer architecture field. These kinds of tools enable the exploration and evaluation of architectural proposals capturing the most relevant aspects of the highly complex systems under…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-02-11 Adrian Colaso , Pablo Prieto , Jose-Angel Herrero , Pablo Abad , Valentin Puente , Jose-Angel Gregorio