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This paper presents a scenario-based model predictive control (MPC) scheme designed to control an evolving pandemic via non-pharmaceutical intervention (NPIs). The proposed approach combines predictions of possible pandemic evolution to…

Systems and Control · Electrical Eng. & Systems 2025-06-24 Domagoj Herceg , Marco DellOro , Riccardo Bertollo , Fuminari Miura , Paul de Klaver , Valentina Breschi , Dinesh Krishnamoorthy , Mauro Salazar

This work presents a Model Predictive Control (MPC) for the artificial pancreas, which is able to autonomously manage basal insulin injections in type 1 diabetic patients. Specifically, the MPC goal is to maintain the patients' blood…

Systems and Control · Electrical Eng. & Systems 2024-01-31 Beatrice Sonzogni , José María Manzano , Marco Polver , Fabio Previdi , Antonio Ferramosca

Objectives. Accurately predicting transitions to anesthetic drugs overdosage is a critical challenge in general anesthesia as it requires the identification of EEG indicators relevant for anticipating the evolution of the depth of…

Neurons and Cognition · Quantitative Biology 2025-12-18 Christophe Sun , Pierre-Olivier Michel , François David , Nathalie Rouach , Dan Longrois , David Holcman

Fluid resuscitation, also called fluid therapy, is commonly used in treatment of critical care patients. Of the variables inherent to fluid therapy treatment, fluid infusion types are well-studied, but volumetric optimization is not.…

Systems and Control · Electrical Eng. & Systems 2023-12-12 Jacob Grant , Hossein Mirinejad

We introduce an entropy-based classification method for pairs of sequences (ECPS) for quantifying mutual dependencies in heart rate and beat-to-beat blood pressure recordings. The purpose of the method is to build a classifier for data in…

Objective: Epilepsy is one of the most prevalent neurological diseases among humans and can lead to severe brain injuries, strokes, and brain tumors. Early detection of seizures can help to mitigate injuries, and can be used to aid the…

Computer Vision and Pattern Recognition · Computer Science 2020-11-20 Theekshana Dissanayake , Tharindu Fernando , Simon Denman , Sridha Sridharan , Clinton Fookes

This paper presents the Adaptive Personalized Control System (APECS) architecture, a novel framework for human-in-the-loop control. An architecture is developed which defines appropriate constraints for the system objectives. A method for…

Systems and Control · Electrical Eng. & Systems 2025-03-14 Marius F. R. Juston , Alex Gisi , William R. Norris , Dustin Nottage , Ahmet Soylemezoglu

Pulse-modulated feedback is utilized in drug dosing to mimic sustained over a longer period of time manual discrete dose administration, the latter is in contrast with continuous drug infusion. The intermittent mode of dosing calls for a…

Dynamical Systems · Mathematics 2025-02-28 Alexander Medvedev , Anton V. Proskurnikov , Zhanybai T. Zhusubaliyev

Control systems used in Minimally Invasive Surgery (MIS) play a crucial role in ensuring preci-sion and safety throughout procedures. This paper presents a control architecture developed for a robotic system designed for MIS operations. The…

A finite-element model is presented for numerical simulation in three dimensions of acoustophoresis of suspended microparticles in a microchannel embedded in a polymer chip and driven by an attached piezoelectric transducer at MHz…

Fluid Dynamics · Physics 2021-07-30 Fabian Lickert , Mathias Ohlin , Henrik Bruus , Pelle Ohlsson

This paper introduces a generative model designed for multimodal control over text-to-image foundation generative AI models such as Stable Diffusion, specifically tailored for engineering design synthesis. Our model proposes parametric,…

Artificial Intelligence · Computer Science 2024-12-09 Rui Zhou , Yanxia Zhang , Chenyang Yuan , Frank Permenter , Nikos Arechiga , Matt Klenk , Faez Ahmed

Inhalers with corticosteroids and muscle relaxants are prescribed by pulmonologists to mitigate bronchospasms that happen due to tightening of the chest. An adhesive patch attached to a patient with chronic obstructive pulmonary disease can…

Robust control design is mainly devoted to guarantee closed-loop stability of a model-based control law in presence of parametric and structural uncertainties. The control law is usually a complex feedback law which is derived from a…

Systems and Control · Computer Science 2011-08-12 Enrico Canuto , Wilber Acuna-Bravo , Andrés Molano-Jimenez , José Ospina , Carlos Perez-Montenegro

This paper introduces a learning-based control framework for a soft robotic actuator system designed to modulate intracranial pressure (ICP) waveforms, which is essential for studying cerebrospinal fluid dynamics and pathological processes…

Injection moulding is a well-established automated process for manufacturing a wide variety of plastic components in large volumes and with high precision. There are, however, process control challenges associated with each stage of…

Systems and Control · Electrical Eng. & Systems 2024-03-08 Mandana Kariminejad , David Tormey , Marion McAfee

Uncertainty and unknown nonlinearity are often inevitable in the suspension systems, which were often solved using fuzzy logic system (FLS) or neural networks (NNs). However, these methods are restricted by the structural complexity of the…

Systems and Control · Electrical Eng. & Systems 2022-04-12 Xiaoyan Hu , Guilin Wen , Shan Yin , Zhao Tan , Zebang Pan

Nonlinear control methodologies have successfully realized stable human-like walking on powered prostheses. However, these methods are typically restricted to model independent controllers due to the unknown human dynamics acting on the…

Robotics · Computer Science 2022-05-06 Rachel Gehlhar , Jenna Reher , Aaron D. Ames

We present the design and \textit{in-silico} evaluation of a closed-loop insulin delivery algorithm to treat type 1 diabetes (T1D) consisting in a data-driven multi-step-ahead blood glucose (BG) predictor integrated into a Linear…

Systems and Control · Electrical Eng. & Systems 2023-07-25 Eleonora Maria Aiello , Mehrad Jaloli , Marzia Cescon

Even though model predictive control (MPC) is currently the main algorithm for insulin control in the artificial pancreas (AP), it usually requires complex online optimizations, which are infeasible for resource-constrained medical devices.…

Machine Learning · Computer Science 2020-03-04 Hongkai Chen , Nicola Paoletti , Scott A. Smolka , Shan Lin

Fractional-order dynamical systems are used to describe processes that exhibit temporal long-term memory and power-law dependence of trajectories. There has been evidence that complex neurophysiological signals like electroencephalogram…

Optimization and Control · Mathematics 2019-10-02 Orlando Romero , Sarthak Chatterjee , Sérgio Pequito