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The human brain undergoes dynamic, potentially pathology-driven, structural changes throughout a lifespan. Longitudinal Magnetic Resonance Imaging (MRI) and other neuroimaging data are valuable for characterizing trajectories of change…

Computer Vision and Pattern Recognition · Computer Science 2025-10-14 Agampreet Aulakh , Nils D. Forkert , Matthias Wilms

Radiologists and doctors make use of X-ray images of the non-dominant hands of children and infants to assess the possibility of genetic conditions and growth abnormalities. This is done by assessing the difference between the actual extent…

Computer Vision and Pattern Recognition · Computer Science 2024-11-18 Nandavardhan R. , Somanathan R. , Vikram Suresh , Savaridassan P

Characterizing in-utero brain development is essential for understanding typical and atypical neurodevelopment. Building on prior spatiotemporal fetal brain MRI atlases, we present the CRL-2025 fetal brain atlas, a spatiotemporal (4D) atlas…

Most segmentation methods in child brain MRI are supervised and are based on global intensity distributions of major brain structures. The successful implementation of a supervised approach depends on availability of an age-appropriate…

Image and Video Processing · Electrical Eng. & Systems 2020-05-21 Nataliya Portman , Paule-J Toussaint , Alan C. Evans

Brain tumor is considered as one of the deadliest and most common form of cancer both in children and in adults. Consequently, determining the correct type of brain tumor in early stages is of significant importance to devise a precise…

Computer Vision and Pattern Recognition · Computer Science 2018-03-05 Parnian Afshar , Arash Mohammadi , Konstantinos N. Plataniotis

Prediction the conversion to early-stage dementia is critical for mitigating its progression but remains challenging due to subtle cognitive impairments and structural brain changes. Traditional T1-weighted magnetic resonance imaging…

Computer Vision and Pattern Recognition · Computer Science 2024-06-28 Yilin Leng , Wenju Cui , Bai Chen , Xi Jiang , Shuangqing Chen , Jian Zheng

Magnetic resonance imaging (MRI) noninvasively provides critical information about how human brain structures develop across stages of life. Developmental scientists are particularly interested in the first few years of neurodevelopment.…

Image and Video Processing · Electrical Eng. & Systems 2021-05-31 Xuzhe Zhang , Xinzi He , Jia Guo , Nabil Ettehadi , Natalie Aw , David Semanek , Jonathan Posner , Andrew Laine , Yun Wang

Neurodegeneration, characterized by the progressive loss of neuronal structure or function, is commonly assessed in clinical practice through reductions in cortical thickness or brain volume, as visualized by structural MRI. While…

Signal Processing · Electrical Eng. & Systems 2025-10-15 Saurabh Sihag , Gonzalo Mateos , Alejandro Ribeiro

Brain segmentation is a fundamental first step in neuroimage analysis. In the case of fetal MRI, it is particularly challenging and important due to the arbitrary orientation of the fetus, organs that surround the fetal head, and…

Many studies on machine learning (ML) for computer-aided diagnosis have so far been mostly restricted to high-quality research data. Clinical data warehouses, gathering routine examinations from hospitals, offer great promises for training…

Image and Video Processing · Electrical Eng. & Systems 2021-04-19 Simona Bottani , Ninon Burgos , Aurélien Maire , Adam Wild , Sebastian Ströer , Didier Dormont , Olivier Colliot

In this study, we propose the use of persistent homology -- specifically Betti curves for brain age prediction and for distinguishing between healthy and pathological aging. The proposed framework is applied to 100 structural MRI scans from…

Neurons and Cognition · Quantitative Biology 2025-11-11 Debanjali Bhattacharya , Neelam Sinha

Purpose: This study investigates whether a machine-learning-based system can predict the rate of cognitive decline in mildly cognitively impaired patients by processing only the clinical and imaging data collected at the initial visit.…

Quantitative Methods · Quantitative Biology 2020-10-07 Sema Candemir , Xuan V. Nguyen , Luciano M. Prevedello , Matthew T. Bigelow , Richard D. White , Barbaros S. Erdal

Autism spectrum disorder (ASD) is a highly disabling mental disease that brings significant impairments of social interaction ability to the patients, making early screening and intervention of ASD critical. With the development of the…

Computer Vision and Pattern Recognition · Computer Science 2025-04-08 Ruimin Ma , Ruitao Xie , Yanlin Wang , Jintao Meng , Yanjie Wei , Wenhui Xi , Yi Pan

Brain imaging of mental health, neurodevelopmental and learning disorders has coupled with machine learning to identify patients based only on their brain activation, and ultimately identify features that generalize from smaller samples of…

Image and Video Processing · Electrical Eng. & Systems 2020-07-21 Laura Tomaz Da Silva , Nathalia Bianchini Esper , Duncan D. Ruiz , Felipe Meneguzzi , Augusto Buchweitz

Neuroanatomical segmentation in magnetic resonance imaging (MRI) of the brain is a prerequisite for volume, thickness and shape measurements. This work introduces a new highly accurate and versatile method based on 3D convolutional neural…

Quantitative Methods · Quantitative Biology 2019-02-07 Philip Novosad , Vladimir Fonov , D. Louis Collins

According to the World Health Organization, the population of children with developmental delays constitutes approximately 6% to 9% of the total population. Based on the number of newborns in Huaibei, Anhui Province, China, in 2023…

Computer Vision and Pattern Recognition · Computer Science 2024-08-06 Zichen Song , Jiakang Li , Songning Lai , Sitan Huang

Detecting and segmenting brain metastases is a tedious and time-consuming task for many radiologists, particularly with the growing use of multi-sequence 3D imaging. This study demonstrates automated detection and segmentation of brain…

Image and Video Processing · Electrical Eng. & Systems 2019-12-30 Endre Grøvik , Darvin Yi , Michael Iv , Elisabeth Tong , Daniel L. Rubin , Greg Zaharchuk

The Convolutional Neural Network has amazed us with its usage on several applications. Age range estimation using CNN is emerging due to its application in myriad of areas which makes it a state-of-the-art area for research and improve the…

Computer Vision and Pattern Recognition · Computer Science 2021-04-20 Dipesh Gyawali , Prashanga Pokharel , Ashutosh Chauhan , Subodh Chandra Shakya

Reliable methods for the neurodevelopmental assessment of infants are essential for early detection of problems that may need prompt interventions. Spontaneous motor activity, or 'kinetics', is shown to provide a powerful surrogate measure…

Computer Vision and Pattern Recognition · Computer Science 2024-12-05 Daniel Holmberg , Manu Airaksinen , Viviana Marchi , Andrea Guzzetta , Anna Kivi , Leena Haataja , Sampsa Vanhatalo , Teemu Roos