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In this paper, we consider the problem of answering count queries for genomic data subject to perfect privacy constraints. Count queries are often used in applications that collect aggregate (population-wide) information from biomedical…

Cryptography and Security · Computer Science 2023-07-04 Bo Jiang , Mohamed Seif , Ravi Tandon , Ming Li

Ensuring the privacy of research participants is vital, even more so in healthcare environments. Deep learning approaches to neuroimaging require large datasets, and this often necessitates sharing data between multiple sites, which is…

Quantitative Methods · Quantitative Biology 2021-06-04 Umang Gupta , Dimitris Stripelis , Pradeep K. Lam , Paul M. Thompson , José Luis Ambite , Greg Ver Steeg

The genome is a unique identifier for human individuals. The genome also contains highly sensitive information, creating a high potential for misuse of genomic data (for example, genetic discrimination). In this paper, I investigated how…

Cryptography and Security · Computer Science 2017-01-12 Isabel Wagner

Dataset obfuscation refers to techniques in which random noise is added to the entries of a given dataset, prior to its public release, to protect against leakage of private information. In this work, dataset obfuscation under two…

Information Theory · Computer Science 2023-05-15 Mahshad Shariatnasab , Farhad Shirani , S. Sitharma Iyengar

We study privacy-utility trade-offs where users share privacy-correlated useful information with a service provider to obtain some utility. The service provider is adversarial in the sense that it can infer the users' private information…

Information Theory · Computer Science 2021-06-29 Xiaoming Duan , Zhe Xu , Rui Yan , Ufuk Topcu

As large language models (LLMs) become progressively more embedded in clinical decision-support, documentation, and patient-information systems, ensuring their privacy and trustworthiness has emerged as an imperative challenge for the…

Cryptography and Security · Computer Science 2025-10-22 Alexander Nemecek , Zebin Yun , Zahra Rahmani , Yaniv Harel , Vipin Chaudhary , Mahmood Sharif , Erman Ayday

With changes in privacy laws, there is often a hard requirement for client data to remain on the device rather than being sent to the server. Therefore, most processing happens on the device, and only an altered element is sent to the…

Cryptography and Security · Computer Science 2022-12-27 Ajinkya K Mulay

Generative machine learning models are being increasingly viewed as a way to share sensitive data between institutions. While there has been work on developing differentially private generative modeling approaches, these approaches…

Cryptography and Security · Computer Science 2022-10-13 Yixi Xu , Sumit Mukherjee , Xiyang Liu , Shruti Tople , Rahul Dodhia , Juan Lavista Ferres

We propose a practical methodology to protect a user's private data, when he wishes to publicly release data that is correlated with his private data, in the hope of getting some utility. Our approach relies on a general statistical…

Cryptography and Security · Computer Science 2015-10-28 Salman Salamatian , Amy Zhang , Flavio du Pin Calmon , Sandilya Bhamidipati , Nadia Fawaz , Branislav Kveton , Pedro Oliveira , Nina Taft

Genetic data collection has become ubiquitous, producing genetic information about health, ancestry, and social traits. However, unregulated use, especially amid evolving scientific understanding, poses serious privacy and discrimination…

Computers and Society · Computer Science 2025-06-03 Vivek Ramanan , Ria Vinod , Cole Williams , Sohini Ramachandran , Suresh Venkatasubramanian

The technical literature about data privacy largely consists of two complementary approaches: formal definitions of conditions sufficient for privacy preservation and attacks that demonstrate privacy breaches. Differential privacy is an…

Cryptography and Security · Computer Science 2025-02-06 Mark Bun , Marco Carmosino , Palak Jain , Gabriel Kaptchuk , Satchit Sivakumar

Deep learning has attracted broad interest in healthcare and medical communities. However, there has been little research into the privacy issues created by deep networks trained for medical applications. Recently developed inference attack…

Machine Learning · Computer Science 2020-11-03 Maoqiang Wu , Xinyue Zhang , Jiahao Ding , Hien Nguyen , Rong Yu , Miao Pan , Stephen T. Wong

DNA sequencing is becoming increasingly commonplace, both in medical and direct-to-consumer settings. To promote discovery, collected genomic data is often de-identified and shared, either in public repositories, such as OpenSNP, or with…

Machine Learning · Computer Science 2022-12-21 Rajagopal Venkatesaramani , Bradley A. Malin , Yevgeniy Vorobeychik

The leakage of data might have been an extreme effect on the personal level if it contains sensitive information. Common prevention methods like encryption-decryption, endpoint protection, intrusion detection system are prone to leakage.…

Cryptography and Security · Computer Science 2020-06-12 Poushali Sengupta , Sudipta Paul , Subhankar Mishra

The amount of personal data collected in our everyday interactions with connected devices offers great opportunities for innovative services fueled by machine learning, as well as raises serious concerns for the privacy of individuals. In…

Machine Learning · Computer Science 2018-03-28 Pierre Dellenbach , Aurélien Bellet , Jan Ramon

Recent advances in DNA sequencing technologies have put ubiquitous availability of fully sequenced human genomes within reach. It is no longer hard to imagine the day when everyone will have the means to obtain and store one's own DNA…

Cryptography and Security · Computer Science 2015-03-19 Pierre Baldi , Roberta Baronio , Emiliano De Cristofaro , Paolo Gasti , Gene Tsudik

In collaborative learning, clients keep their data private and communicate only the computed gradients of the deep neural network being trained on their local data. Several recent attacks show that one can still extract private information…

Machine Learning · Computer Science 2022-07-26 Fan Mo , Anastasia Borovykh , Mohammad Malekzadeh , Soteris Demetriou , Deniz Gündüz , Hamed Haddadi

Objective: To enable privacy-preserving learning of high quality generative and discriminative machine learning models from distributed electronic health records. Methods and Results: We describe general and scalable strategy to build…

Cryptography and Security · Computer Science 2018-06-19 Marina Blanton , Ah Reum Kang , Subhadeep Karan , Jaroslaw Zola

The rise of connected personal devices together with privacy concerns call for machine learning algorithms capable of leveraging the data of a large number of agents to learn personalized models under strong privacy requirements. In this…

Machine Learning · Computer Science 2018-02-20 Aurélien Bellet , Rachid Guerraoui , Mahsa Taziki , Marc Tommasi

In the electricity grid, networked sensors which record and transmit increasingly high-granularity data are being deployed. In such a setting, privacy concerns are a natural consideration. We present an attack model for privacy breaches,…

Optimization and Control · Mathematics 2014-06-02 Lillian J. Ratliff , Roy Dong , Henrik Ohlsson , Alvaro A. Cardenas , S. Shankar Sastry