Related papers: Constrained tensor factorization for computational…
Extracting genetic information from a full range of sequencing data is important for understanding diseases. We propose a novel method to effectively explore the landscape of genetic mutations and aggregate them to predict cancer type. We…
In this study, we introduce ExBEHRT, an extended version of BEHRT (BERT applied to electronic health records), and apply different algorithms to interpret its results. While BEHRT considers only diagnoses and patient age, we extend the…
This paper primarily addresses a dataset relating to cellular, chemical and physical conditions of patients gathered at the time they are operated upon to remove colorectal tumours. This data provides a unique insight into the biochemical…
Brain tumors are one of the most common and dangerous neurological diseases which require a timely and correct diagnosis to provide the right treatment procedures. Even with the promotion of magnetic resonance imaging (MRI), the process of…
Breast cancer is one of the common cancers that endanger the health of women globally. Accurate target lesion segmentation is essential for early clinical intervention and postoperative follow-up. Recently, many convolutional neural…
Gastric cancer and Colon adenocarcinoma represent widespread and challenging malignancies with high mortality rates and complex treatment landscapes. In response to the critical need for accurate prognosis in cancer patients, the medical…
Accurately predicting the survival of cancer patients is crucial for personalized treatment. However, existing studies focus solely on the relationships between samples with known survival risks, without fully leveraging the value of…
The widespread digitization of patient data via electronic health records (EHRs) has created an unprecedented opportunity to use machine learning algorithms to better predict disease risk at the patient level. Although predictive models…
Late diagnosis and high costs are key factors that negatively impact the care of cancer patients worldwide. Although the availability of biological markers for the diagnosis of cancer type is increasing, costs and reliability of tests…
Cancer pathology is unique to a given individual, and developing personalized diagnostic and treatment protocols are a primary concern. Mathematical modeling and simulation is a promising approach to personalized cancer medicine. Yet, the…
Given multi-platform genome data with prior knowledge of functional gene sets, how can we extract interpretable latent relationships between patients and genes? More specifically, how can we devise a tensor factorization method which…
The approval success rate of drug candidates is very low with the majority of failure due to safety and efficacy. Increasingly available high dimensional information on targets, drug molecules and indications provides an opportunity for ML…
Breast cancer survival prediction in computational pathology presents a remarkable challenge due to tumor heterogeneity. For instance, different regions of the same tumor in the pathology image can show distinct morphological and molecular…
Head and Neck Squamous Cell Carcinoma (HNSCC) is one of cancer type that is most distressing leading to acute pain, effecting speech and primary survival functions such as swallowing and breathing. The morbidity and mortality of HNSCC…
We propose a new methodology for selecting and ranking covariates associated with a variable of interest in a context of high-dimensional data under dependence but few observations. The methodology successively intertwines the clustering of…
Computational pathology is part of precision oncology medicine. The integration of high-throughput data including genomics, transcriptomics, proteomics, metabolomics, pathomics, and radiomics into clinical practice improves cancer treatment…
Esophageal cancer is a major cause of cancer-related mortality internationally, with high recurrence rates and poor survival even among patients treated with curative-intent surgery. Investigating relevant prognostic factors and predicting…
Brain tumors analysis is important in timely diagnosis and effective treatment to cure patients. Tumor analysis is challenging because of tumor morphology like size, location, texture, and heteromorphic appearance in the medical images. In…
Automated brain tumor detection is becoming a highly considerable medical diagnosis research. In recent medical diagnoses, detection and classification are highly considered to employ machine learning and deep learning techniques.…
According to the World Health Organization (WHO), cancer is the second leading cause of death globally. Scientific research on different types of cancers grows at an ever-increasing rate, publishing large volumes of research articles every…