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Artificial Intelligence (AI) is rapidly integrating into various aspects of our daily lives, influencing decision-making processes in areas such as targeted advertising and matchmaking algorithms. As AI systems become increasingly…

Artificial Intelligence · Computer Science 2025-03-11 Md. Tanzib Hosain , Mehedi Hasan Anik , Sadman Rafi , Rana Tabassum , Khaleque Insia , Md. Mehrab Siddiky

The rise of powerful large language models (LLMs) brings about tremendous opportunities for innovation but also looming risks for individuals and society at large. We have reached a pivotal moment for ensuring that LLMs and LLM-infused…

Human-Computer Interaction · Computer Science 2023-08-09 Q. Vera Liao , Jennifer Wortman Vaughan

Artificial intelligence (AI) has huge potential to improve the health and well-being of people, but adoption in clinical practice is still limited. Lack of transparency is identified as one of the main barriers to implementation, as…

Artificial Intelligence · Computer Science 2021-01-06 Aniek F. Markus , Jan A. Kors , Peter R. Rijnbeek

Machine learning (ML), artificial intelligence (AI) and other modern statistical methods are providing new opportunities to operationalize previously untapped and rapidly growing sources of data for patient benefit. Whilst there is a lot of…

The complex nature of disease mechanisms and the variability of patient symptoms pose significant challenges in developing effective diagnostic tools. Although machine learning (ML) has made substantial advances in medical diagnosis, the…

In reaction to growing concerns about the potential harms of artificial intelligence (AI), societies have begun to demand more transparency about how AI models and systems are created and used. To address these concerns, several efforts…

Computers and Society · Computer Science 2024-03-13 David Piorkowski , John Richards , Michael Hind

This paper claims that machine learning models deployed in high stakes domains such as medicine must be interpretable, shareable, reproducible and accountable. We argue that these principles should form the foundational design criteria for…

Machine Learning · Computer Science 2025-08-25 Ayyüce Begüm Bektaş , Mithat Gönen

Machine learning (ML) is increasingly being used in image retrieval systems for medical decision making. One application of ML is to retrieve visually similar medical images from past patients (e.g. tissue from biopsies) to reference when…

The rise of machine learning (ML) is accompanied by several high-profile cases that have stressed the need for fairness, accountability, explainability and trust in ML systems. The existing literature has largely focused on fully automated…

Computers and Society · Computer Science 2023-06-14 Bhavya Ghai

Remarkable success of modern image-based AI methods and the resulting interest in their applications in critical decision-making processes has led to a surge in efforts to make such intelligent systems transparent and explainable. The need…

Artificial Intelligence · Computer Science 2020-11-30 Adriano Lucieri , Muhammad Naseer Bajwa , Andreas Dengel , Sheraz Ahmed

In spite of the strong performance of machine learning (ML) models in radiology, they have not been widely accepted by radiologists, limiting clinical integration. A key reason is the lack of explainability, which ensures that model…

Human-Computer Interaction · Computer Science 2026-04-14 Sara Ketabi , Matthias W. Wagner , Birgit Betina Ertl-Wagner , Greg A. Jamieson , Farzad Khalvati

Advances in computing power, deep learning architectures, and expert labelled datasets have spurred the development of medical imaging artificial intelligence systems that rival clinical experts in a variety of scenarios. The National…

Image and Video Processing · Electrical Eng. & Systems 2021-11-18 Rohan Shad , John P. Cunningham , Euan A. Ashley , Curtis P. Langlotz , William Hiesinger

The integration of artificial intelligence (AI) into medicine is remarkable, offering advanced diagnostic and therapeutic possibilities. However, the inherent opacity of complex AI models presents significant challenges to their clinical…

Computer Vision and Pattern Recognition · Computer Science 2025-09-23 Binbin Wen , Yihang Wu , Tareef Daqqaq , Ahmad Chaddad

Artificial intelligence (AI) provides many opportunities to improve private and public life. Discovering patterns and structures in large troves of data in an automated manner is a core component of data science, and currently drives…

Machine Learning · Computer Science 2020-09-25 Vaishak Belle , Ioannis Papantonis

A central goal of explainable artificial intelligence (XAI) is to improve the trust relationship in human-AI interaction. One assumption underlying research in transparent AI systems is that explanations help to better assess predictions of…

Artificial Intelligence · Computer Science 2021-06-23 Felix Biessmann , Viktor Treu

Artificial intelligence (AI) systems utilizing deep neural networks (DNNs) and machine learning (ML) algorithms are widely used for solving important problems in bioinformatics, biomedical informatics, and precision medicine. However,…

Quantitative Methods · Quantitative Biology 2023-02-24 Md. Rezaul Karim , Tanhim Islam , Oya Beyan , Christoph Lange , Michael Cochez , Dietrich Rebholz-Schuhmann , Stefan Decker

Would you trust physicians if they cannot explain their decisions to you? Medical diagnostics using machine learning gained enormously in importance within the last decade. However, without further enhancements many state-of-the-art machine…

Machine Learning · Computer Science 2022-06-01 Emanuel Slany , Yannik Ott , Stephan Scheele , Jan Paulus , Ute Schmid

Machine learning is expected to fuel significant improvements in medical care. To ensure that fundamental principles such as beneficence, respect for human autonomy, prevention of harm, justice, privacy, and transparency are respected,…

The translation of artificial intelligence (AI) systems into clinical practice requires bridging fundamental gaps between explainable AI theory, clinician expectations, and governance requirements. While conceptual frameworks define what…

Computers and Society · Computer Science 2025-11-05 Alexander Bakumenko , Aaron J. Masino , Janine Hoelscher

Machine learning and many of its applications are considered hard to approach due to their complexity and lack of transparency. One mission of human-centric machine learning is to improve algorithm transparency and user satisfaction while…

Human-Computer Interaction · Computer Science 2019-10-25 Zhiwei Han , Thomas Weber , Stefan Matthes , Yuanting Liu , Hao Shen
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