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Related papers: A Hessian Geometric Structure of Chemical Thermody…

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We derive the Hessian geometric structure of nonequilibrium chemical reaction networks (CRN) on the flux and force spaces induced by the Legendre duality of convex dissipation functions and characterize their dynamics as a generalized flow.…

Chemical Physics · Physics 2022-06-03 Tetsuya J. Kobayashi , Dimitri Loutchko , Atsushi Kamimura , Yuki Sughiyama

The theory of chemical kinetics form the basis to describe the dynamics of chemical systems. Owing to physical and thermodynamic constraints, chemical reaction systems possess various structures, which can be utilized to characterize…

Biological Physics · Physics 2022-01-03 Tetsuya J. Kobayashi , Dimitri Loutchko , Atsushi Kamimura , Yuki Sughiyama

Recently, Hessian geometry - an extension of information geometry - has emerged as a framework to naturally connect the geometries appearing in the theory of chemical reaction networks (CRN) to their inherent thermodynamical and kinetic…

Statistical Mechanics · Physics 2023-08-10 Dimitri Loutchko , Yuki Sughiyama , Tetsuya J. Kobayashi

Information geometry is based on classical Legendre duality but allows to incorporate additional structure such as algebraic constraints and Bregman divergence functions. It is naturally suited, and has been successfully used, to describe…

Molecular Networks · Quantitative Biology 2025-03-26 Dimitri Loutchko , Yuki Sughiyama , Tetsuya J. Kobayashi

We address a fundamental question: under which conditions do the dynamics and thermodynamics of open chemical reaction networks (CRNs), grounded on the notion of idealized chemostats that exchange selected species, emerge from underlying…

Statistical Mechanics · Physics 2026-04-17 Benedikt Remlein , Massimiliano Esposito , Francesco Avanzini

A natural condition on the structure of the underlying chemical reaction network, namely weak reversibility, is shown to guarantee the existence of an equilibrium (steady state) in each positive stoichiometric compatibility class for the…

Quantitative Methods · Quantitative Biology 2011-11-14 Jian Deng , Christopher Jones , Martin Feinberg , Adrian Nachman

This article deals with the problem of maximizing the production of a species for a chemical network by controlling the temperature. Under the so-called mass kinetics assumption the system can be modeled as a single-input control system…

Optimization and Control · Mathematics 2020-01-14 Bernard Bonnard , Jérémy Rouot

We consider growing open chemical reaction systems (CRSs), in which autocatalytic chemical reactions are encapsulated in a finite volume and its size can change in conjunction with the reactions. The thermodynamics of growing CRSs is…

Statistical Mechanics · Physics 2022-08-30 Yuki Sughiyama , Atsushi Kamimura , Dimitri Loutchko , Tetsuya J. Kobayashi

Understanding the emergent behavior of chemical reaction networks (CRNs) is a fundamental aspect of biology and its origin from inanimate matter. A closed CRN monotonically tends to thermal equilibrium, but when it is opened to external…

Molecular Networks · Quantitative Biology 2024-05-16 Masanari Shimada , Pegah Behrad , Eric De Giuli

The modern thermodynamics of discrete systems is based on graph theory, which provides both algebraic methods to define observables and a geometric intuition of their meaning and role. However, because chemical reactions are usually…

Statistical Mechanics · Physics 2023-04-04 Sara Dal Cengio , Vivien Lecomte , Matteo Polettini

Living systems operate out of equilibrium, continuously consuming energy to sustain organised, functional states. Their emergent behaviour usually relies on a set of interconnected chemical reaction networks (CRNs) driven by external fluxes…

Statistical Mechanics · Physics 2026-02-03 Shiling Liang , Paolo De Los Rios , Daniel Maria Busiello

For chemical reaction networks described by a master equation, we define energy and entropy on a stochastic trajectory and develop a consistent nonequilibrium thermodynamic description along a single stochastic trajectory of reaction…

Statistical Mechanics · Physics 2009-11-11 Tim Schmiedl , Udo Seifert

Motivated by recent progress on the interplay between graph theory, dynamics, and systems theory, we revisit the analysis of chemical reaction networks described by mass action kinetics. For reaction networks possessing a thermodynamic…

Optimization and Control · Mathematics 2012-06-19 Arjan van der Schaft , Shodhan Rao , Bayu Jayawardhana

Power law dynamics is used to describe the stability behavior in metabolic networks such as chemical reaction networks (CRN's). These systems allow multiple steady states within a single stoichiometric class. On the other side thermodynamic…

Dynamical Systems · Mathematics 2020-07-10 Gunther Friedrich Neumann

It is essential that mesoscopic simulations of reactive systems reproduce the correct statistical distributions at thermodynamic equilibrium. By considering a compressible fluctuating hydrodynamics (FHD) simulation method of ideal gas…

The catalytic reaction system (CRS) formalism by Hordijk and Steel is a versatile method to model autocatalytic biochemical reaction networks. It is particularly suited, and has been widely used, to study self-sustainment and…

Molecular Networks · Quantitative Biology 2023-08-16 Dimitri Loutchko

All current formulations of nonequilibrium thermodynamics of open chemical reaction networks rely on the assumption of non-interacting species. We develop a general theory which accounts for interactions between chemical species within a…

Statistical Mechanics · Physics 2021-03-09 Francesco Avanzini , Emanuele Penocchio , Gianmaria Falasco , Massimiliano Esposito

A chemical reaction network (CRN) is composed of reactions that can be seen as interactions among entities called species, which exist within the system. Endowed with kinetics, CRN has a corresponding set of ordinary differential equations…

Dynamical Systems · Mathematics 2021-04-20 Bryan S. Hernandez , Ralph John L. De la Cruz

In this note we report some advances in the study of thermodynamic formalism for a class of partially hyperbolic system -- center isometries, that includes regular elements in Anosov actions. The techniques are of geometric flavor (in…

Dynamical Systems · Mathematics 2021-03-19 Pablo D. Carrasco , Federico Rodriguez-Hertz

We investigate the nonequilibrium stationary states of systems consisting of chemical reactions among molecules of several chemical species. To this end we introduce and develop a stochastic formulation of nonequilibrium thermodynamics of…

Statistical Mechanics · Physics 2018-07-04 Tânia Tomé , Mário J. de Oliveira
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