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For decades, researchers have been applying computer simulation to address problems in biology. However, many of these "grand challenges" in computational biology, such as simulating how proteins fold, remained unsolved due to their great…

Biological Physics · Physics 2009-01-08 Stefan M. Larson , Christopher D. Snow , Michael Shirts , Vijay S. Pande

The relation between entropy and information has great significance for computation. Based on the strict reversibility of the laws of microphysics, Landauer (1961), Bennett (1973), Priese (1976), Fredkin and Toffoli (1982), Feynman (1985)…

Quantum Physics · Physics 2021-11-16 Basil Evangelidis

Reversible computation has been recognised as a potential solution to the technological bottleneck in the future of computing machinery. Rolf Landauer determined the lower limit for power dissipation in computation and noted that…

Emerging Technologies · Computer Science 2019-11-18 Harun Siljak , Julien de Rosny , Mathias Fink

The derivation of general performance benchmarks is important in the design of highly optimized heat engines and refrigerators. To obtain them, one may model phenomenologically the leading sources of irreversibility ending up with results…

Quantum Physics · Physics 2015-01-06 Luis A. Correa , José P. Palao , Gerardo Adesso , Daniel Alonso

A proposal for a magnetic quantum processor that consists of individual molecular spins coupled to superconducting coplanar resonators and transmission lines is carefully examined. We derive a simple magnetic quantum electrodynamics…

Materials Science · Physics 2016-11-02 M. D. Jenkins , D. Zueco , O. Roubeau , G. Aromí , J. Majer , F. Luis

Energy consumption in solving computational problems has been gaining growing attention as one of the key performance measures for computers. Quantum computation is known to offer advantages over classical computation in terms of various…

Quantum Physics · Physics 2025-05-23 Florian Meier , Hayata Yamasaki

Interest in the thermodynamics of computation has revived in recent years, driven by developments in science, economics and technology. Given the consequences of the growing demand for computational power, the idea of reducing the energy…

Statistical Mechanics · Physics 2018-12-31 Thomas E Ouldridge , Rory A. Brittain , Pieter Rein ten Wolde

The challenge in building high-fidelity quantum gates lies in overcoming control errors and decoherence effects caused by the coupling between the quantum system and the external environment. Nonadiabatic holonomic quantum computation uses…

Quantum Physics · Physics 2025-11-04 Yue Heng Liu , Qi Li

Power loss in the electronic system is a very crucial limiting factor that can be reduced or minimized with the help of using the reversible logics "a concept came from Thermodynamics". In this paper the authors shows the concept of…

Other Computer Science · Computer Science 2012-05-29 Pradeep Singla , Satyan

It is now well established that there is no lower bound for the energy dissipated during a computation. The relevance of the zero-energy limit is unclear, however, because it entails computations that are unreliable or infinitely slow, or…

Statistical Mechanics · Physics 2018-02-21 Dominique Chu

Near zero-energy computing describes the concept of executing logic operations below the (kBT ln 2) energy limit. Landauer discussed that it is impossible to break this limit as long as the computations are performed in the conventional,…

Emerging Technologies · Computer Science 2020-08-18 Frank Sill Torres , Philipp Niemann , Robert Wille , Rolf Drechsler

Since reversible computing requires preservation of all information throughout the entire computational process, this implies that all errors that appear as a result of the interaction of the information-carrying system with uncontrolled…

Quantum Physics · Physics 2009-11-13 Lev B. Levitin , Tommaso Toffoli

quest for processing speed potential. In fact, we always get a fraction of the technically available computing power (so-called {\em theoretical peak}), and the gap is likely to go hand-to-hand with the hardware complexity of the target…

Distributed, Parallel, and Cluster Computing · Computer Science 2021-06-23 Claude Tadonki

Quantum computers can in principle solve certain problems exponentially more quickly than their classical counterparts. We have not yet reached the advent of useful quantum computation, but when we do, it will affect nearly all scientific…

In current molecular communication (MC) systems, performing computational operations at the nanoscale remains challenging, restricting their applicability in complex scenarios such as adaptive biochemical control and advanced nanoscale…

Signal Processing · Electrical Eng. & Systems 2025-03-03 Jianqiao Long , Lei Zhang , Miaowen Wen , Kezhi Wang , Natalio Krasnogor , Jichun Li

The present level of development of molecular force field methods is assessed from the point of view of simulation-based engineering, outlining the immediate perspective for further development and highlighting the newly emerging discipline…

Distributed, Parallel, and Cluster Computing · Computer Science 2013-05-22 Martin Horsch , Christoph Niethammer , Jadran Vrabec , Hans Hasse

During recent years, quantum computers have received increasing attention, primarily due to their ability to significantly increase computational performance for specific problems. Computational performance could be improved for…

Quantum Physics · Physics 2024-11-12 Ludger Leenders , Martin Sollich , Christiane Reinert , André Bardow

Advantages of quantum effects in several technologies, such as computation and communication, have already been well appreciated, and some devices, such as quantum computers and communication links, exhibiting superiority to their classical…

Quantum Physics · Physics 2020-11-03 Aslı Tuncer , Özgür E. Müstecaplioğlu

Design considerations for molecular dynamics algorithms capable of taking advantage of the computational power of a graphics processing unit (GPU) are described. Accommodating the constraints of scalable streaming-multiprocessor hardware…

Computational Physics · Physics 2011-01-27 D. C. Rapaport

Landauer's principle bounds the heat generated by logical operations, but in practice the thermodynamic cost of computation is dominated by the control systems that implement logic. CMOS gates dissipate energy far above the Landauer bound,…

Statistical Mechanics · Physics 2026-02-17 Stephen Whitelam