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Access to electronic health record (EHR) data has motivated computational advances in medical research. However, various concerns, particularly over privacy, can limit access to and collaborative use of EHR data. Sharing synthetic EHR data…

Machine Learning · Computer Science 2018-01-15 Edward Choi , Siddharth Biswal , Bradley Malin , Jon Duke , Walter F. Stewart , Jimeng Sun

Sensitive medical data is often subject to strict usage constraints. In this paper, we trained a generative adversarial network (GAN) on real-world electronic health records (EHR). It was then used to create a data-set of "fake" patients…

Machine Learning · Computer Science 2021-09-07 John Weldon , Tomas Ward , Eoin Brophy

Synthetic health data have the potential to mitigate privacy concerns when sharing data to support biomedical research and the development of innovative healthcare applications. Modern approaches for data generation based on machine…

Machine Learning · Computer Science 2023-01-11 Chao Yan , Yao Yan , Zhiyu Wan , Ziqi Zhang , Larsson Omberg , Justin Guinney , Sean D. Mooney , Bradley A. Malin

Electronic Health Records (EHRs) are a valuable asset to facilitate clinical research and point of care applications; however, many challenges such as data privacy concerns impede its optimal utilization. Deep generative models,…

Machine Learning · Computer Science 2024-01-12 Ghadeer Ghosheh , Jin Li , Tingting Zhu

The widespread adoption of electronic health records and digital healthcare data has created a demand for data-driven insights to enhance patient outcomes, diagnostics, and treatments. However, using real patient data presents privacy and…

Machine Learning · Computer Science 2023-11-15 Aryan Jadon , Shashank Kumar

Access to medical data is highly restricted due to its sensitive nature, preventing communities from using this data for research or clinical training. Common methods of de-identification implemented to enable the sharing of data are…

Signal Processing · Electrical Eng. & Systems 2019-09-23 Anne Marie Delaney , Eoin Brophy , Tomas E. Ward

Preservation of private user data is of paramount importance for high Quality of Experience (QoE) and acceptability, particularly with services treating sensitive data, such as IT-based health services. Whereas anonymization techniques were…

Machine Learning · Computer Science 2024-03-04 Navid Ashrafi , Vera Schmitt , Robert P. Spang , Sebastian Möller , Jan-Niklas Voigt-Antons

Sharing electronic health records (EHRs) on a large scale may lead to privacy intrusions. Recent research has shown that risks may be mitigated by simulating EHRs through generative adversarial network (GAN) frameworks. Yet the methods…

Machine Learning · Computer Science 2020-03-25 Chao Yan , Ziqi Zhang , Steve Nyemba , Bradley A. Malin

Privacy concerns around sharing personally identifiable information are a major practical barrier to data sharing in medical research. However, in many cases, researchers have no interest in a particular individual's information but rather…

Image and Video Processing · Electrical Eng. & Systems 2021-08-18 August DuMont Schütte , Jürgen Hetzel , Sergios Gatidis , Tobias Hepp , Benedikt Dietz , Stefan Bauer , Patrick Schwab

Synthetic Electronic Health Records (EHR) have emerged as a pivotal tool in advancing healthcare applications and machine learning models, particularly for researchers without direct access to healthcare data. Although existing methods,…

In recent years, deep learning has been successfully adopted in a wide range of applications related to electronic health records (EHRs) such as representation learning and clinical event prediction. However, due to privacy constraints,…

Machine Learning · Computer Science 2023-09-04 Chang Lu , Chandan K. Reddy , Ping Wang , Dong Nie , Yue Ning

Wound prognostic models not only provide an estimate of wound healing time to motivate patients to follow up their treatments but also can help clinicians to decide whether to use a standard care or adjuvant therapies and to assist them…

Artificial Intelligence · Computer Science 2022-01-03 Farnaz H. Foomani , D. M. Anisuzzaman , Jeffrey Niezgoda , Jonathan Niezgoda , William Guns , Sandeep Gopalakrishnan , Zeyun Yu

Synthetic data generation offers a promising solution to enhance the usefulness of Electronic Healthcare Records (EHR) by generating realistic de-identified data. However, the existing literature primarily focuses on the quality of…

Machine Learning · Computer Science 2024-04-29 Resmi Ramachandranpillai , Md Fahim Sikder , David Bergström , Fredrik Heintz

Synthetic Electronic Health Records (EHRs) offer a valuable opportunity to create privacy preserving and harmonized structured data, supporting numerous applications in healthcare. Key benefits of synthetic data include precise control over…

Computation and Language · Computer Science 2025-04-28 Yihan Lin , Zhirong Bella Yu , Simon Lee

Electrocardiogram (ECG) datasets tend to be highly imbalanced due to the scarcity of abnormal cases. Additionally, the use of real patients' ECGs is highly regulated due to privacy issues. Therefore, there is always a need for more ECG…

Machine Learning · Computer Science 2022-08-25 Edmond Adib , Fatemeh Afghah , John J. Prevost

The limited data availability due to strict privacy regulations and significant resource demands severely constrains biomedical time-series AI development, which creates a critical gap between data requirements and accessibility. Synthetic…

Machine Learning · Computer Science 2025-11-25 Youngjoon Lee , Seongmin Cho , Yehhyun Jo , Jinu Gong , Hyunjoo Jenny Lee , Joonhyuk Kang

Machine learning (ML) and Natural Language Processing (NLP) have achieved remarkable success in many fields and have brought new opportunities and high expectation in the analyses of medical data. The most common type of medical data is the…

Computation and Language · Computer Science 2018-12-10 Jiaqi Guan , Runzhe Li , Sheng Yu , Xuegong Zhang

Electronic Health Records (EHRs) contain sensitive patient information, which presents privacy concerns when sharing such data. Synthetic data generation is a promising solution to mitigate these risks, often relying on deep generative…

Machine Learning · Computer Science 2023-08-11 Taha Ceritli , Ghadeer O. Ghosheh , Vinod Kumar Chauhan , Tingting Zhu , Andrew P. Creagh , David A. Clifton

Time series in Electronic Health Records (EHRs) present unique challenges for generative models, such as irregular sampling, missing values, and high dimensionality. In this paper, we propose a novel generative adversarial network (GAN)…

Machine Learning · Computer Science 2024-02-12 Hojjat Karami , Mary-Anne Hartley , David Atienza , Anisoara Ionescu

High-quality synthetic data can support the development of effective predictive models for biomedical tasks, especially in rare diseases or when subject to compelling privacy constraints. These limitations, for instance, negatively impact…

Machine Learning · Computer Science 2023-01-24 Lorenzo Simone , Davide Bacciu
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