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The level-set method of topology optimization is used to design isotropic two-phase periodic multifunctional composites in three dimensions. One phase is stiff and insulating whereas the other is conductive and mechanically compliant. The…

Materials Science · Physics 2007-12-20 V. J. Challis , A. P. Roberts , A. H. Wilkins

Self-folding is an emerging paradigm for the inverse design of three-dimensional structures. While most efforts have concentrated on the shape of the net, our approach introduces a new design dimension-bond specificity between the edges. We…

Soft Condensed Matter · Physics 2025-01-14 Diogo E. P. Pinto , Nuno A. M. Araújo , Petr Šulc , John Russo

We introduce a continuous modeling approach which combines elastic responds of the trabecular bone structure, the concentration of signaling molecules within the bone and a mechanism how this concentration at the bone surface is used for…

Tissues and Organs · Quantitative Biology 2017-11-21 S. Aland , F. Stenger , R. Müller , M. Kampschulte , A. C. Langheinrich , T. El Khassawna , C. Heiß , A. Dreutsch , A. Voigt

Diffusion models are important in tissue engineering as they enable an understanding of molecular delivery to cells in tissue constructs. As three-dimensional (3D) tissue constructs become larger, more intricate, and more clinically…

Tissues and Organs · Quantitative Biology 2015-12-22 Richard J. McMurtrey

We propose a new algorithm for the design of topologically optimized lightweight structures, under a minimum compliance requirement. The new process enhances a standard level set formulation in terms of computational efficiency, thanks to…

Computational Engineering, Finance, and Science · Computer Science 2022-08-24 Davide Cortellessa , Nicola Ferro , Simona Perotto , Stefano Micheletti

Progresses in additive manufacturing technologies allow the realization of finely graded microstructured materials with tunable mechanical properties. This paves the way to a wealth of innovative applications, calling for the combined…

Analysis of PDEs · Mathematics 2023-07-10 Stefano Almi , Ulisse Stefanelli

We present a novel continuous optimization method to the discrete problem of quadtree optimization. The optimization aims at achieving a quadtree structure with the highest mechanical stiffness, where the edges in the quadtree are…

Numerical Analysis · Mathematics 2018-05-23 Jun Wu

Topology Optimization seeks to find the best design that satisfies a set of constraints while maximizing system performance. Traditional iterative optimization methods like SIMP can be computationally expensive and get stuck in local…

Machine Learning · Computer Science 2023-03-20 Giorgio Giannone , Faez Ahmed

In order to increase the bone forming ability of MBG-PCL composite scaffold, microporosity was created in the struts of 3D-printed MBG-PCL scaffolds for the manufacturing of a construct with a multiscale porosity consisting of meso-, micro-…

Tissues and Organs · Quantitative Biology 2021-04-06 M. Natividad Gomez-Cerezo , Juan Pena , Saso Ivanovski , Daniel Arcos , Maria Vallet-Regi , Cedryck Vaquette

This paper proposes a self-support topology optimization method that considers distortion to improve the manufacturability of additive manufacturing. First, a self-support constraint is proposed that combines an overhang angle constraint…

Computational Engineering, Finance, and Science · Computer Science 2022-12-15 Takao Miki

Although stress-constrained topology optimization has been extensively studied in structural design, the development of optimization frameworks to enable the creation of metamaterials with optimal mechanical performance is still an open…

Computational Engineering, Finance, and Science · Computer Science 2026-02-24 Yanda Chen , Sebastian Rodriguez , Beatriz Moya , Francisco Chinesta

We discuss a topology optimization problem for an elastoplastic medium. The distribution of material in a region is optimized with respect to a given target functional taking into account compliance. The incremental elastoplastic problem…

Optimization and Control · Mathematics 2020-11-02 Stefano Almi , Ulisse Stefanelli

We present a two-scale topology optimization framework for the design of macroscopic bodies with an optimized elastic response, which is achieved by means of a spatially-variant cellular architecture on the microscale. The chosen spinodoid…

Computational Engineering, Finance, and Science · Computer Science 2021-05-21 Li Zheng , Siddhant Kumar , Dennis M. Kochmann

In the pursuit of designing safer and more efficient energy-absorbing structures, engineers must tackle the challenge of improving crush performance while balancing multiple conflicting objectives, such as maximising energy absorption and…

Materials Science · Physics 2025-02-25 Hirak Kansara , Siamak F. Khosroshahi , Leo Guo , Miguel A. Bessa , Wei Tan

The project aims to explore a novel way to design and produce cellular materials with good energy absorption and recoverability properties. Spinodoid structures offer an alternative to engineering structures such as honeycombs and foam with…

In the current industry, the development of optimized mechanical components able to satisfy the customer requirements evolves quickly. Therefore, companies are asked for efficient solutions to improve their products in terms of stiffness…

Computational Engineering, Finance, and Science · Computer Science 2023-07-31 Rafael Merli , Antolín Martínez-Martínez , Juan José Ródenas , Marc Bosch-Galera , Enrique Nadal

Reliability-based design optimization (RBDO) provides a rational and sound framework for finding the optimal design while taking uncertainties into ac-count. The main issue in implementing RBDO methods, particularly stochastic simu-lation…

Applications · Statistics 2020-03-03 Wang-Sheng Liu , Sai Hung Cheung

Retrieving 3D bone anatomy from biplanar X-ray images is crucial since it can significantly reduce radiation exposure compared to traditional CT-based methods. Although various deep learning models have been proposed to address this complex…

Image and Video Processing · Electrical Eng. & Systems 2024-07-23 Jixiang Chen , Yiqun Lin , Haoran Sun , Xiaomeng Li

Joint injuries, and their long-term consequences, present a substantial global health burden. Wearable prophylactic braces are an attractive potential solution to reduce the incidence of joint injuries by limiting joint movements that are…

The optimal and robust design of structures has gained much attention in the past ten years due to the ever increasing need for manufacturers to build robust systems at the lowest cost. Reliability-based design optimization (RBDO) allows…

Applications · Statistics 2017-04-12 Vincent Dubourg , Jean-Marc Bourinet , Bruno Sudret