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Molecular docking is a key computational tool utilized to predict the binding conformations of small molecules to protein targets, which is fundamental in the design of novel drugs. Despite recent advancements in geometric deep…

Biomolecules · Quantitative Biology 2023-12-01 Jiaxian Yan , Zaixi Zhang , Kai Zhang , Qi Liu

To facilitate flexible and efficient structural bioinformatics analyses, new functionality for three-dimensional structure processing and analysis has been introduced into PyCogent -- a popular feature-rich framework for sequence-based…

Biomolecules · Quantitative Biology 2018-10-01 Marcin Cieslik , Zygmunt Derewenda , Cameron Mura

QMKPy provides a Python framework for modeling and solving the quadratic multiple knapsack problem (QMKP). It is primarily aimed at researchers who develop new solution algorithms for the QMKP. QMKPy therefore mostly functions as a testbed…

Other Computer Science · Computer Science 2022-12-01 Karl-Ludwig Besser , Eduard A. Jorswieck

Laboratory tests play a major role in clinical decision making because they are essential for the confirmation of diagnostics suspicions and influence medical decisions. The number of different laboratory tests available to physicians in…

Machine Learning · Computer Science 2021-05-05 Fabián Villena

Array programming provides a powerful, compact, expressive syntax for accessing, manipulating, and operating on data in vectors, matrices, and higher-dimensional arrays. NumPy is the primary array programming library for the Python…

One major challenge in science is to make all results potentially reproducible. Thus, along with the raw data, every step from basic processing of the data, evaluation, to the generation of the figures, has to be documented as clearly as…

Graphics · Computer Science 2020-07-31 Richard Gerum

With the increased availability of rich tactile sensors, there is an equally proportional need for open-source and integrated software capable of efficiently and effectively processing raw touch measurements into high-level signals that can…

Robotics · Computer Science 2021-05-28 Mike Lambeta , Huazhe Xu , Jingwei Xu , Po-Wei Chou , Shaoxiong Wang , Trevor Darrell , Roberto Calandra

Software frameworks for neural networks play a key role in the development and application of deep learning methods. In this paper, we introduce the Chainer framework, which intends to provide a flexible, intuitive, and high performance…

Software developers use Application Programming Interfaces (APIs) of libraries and frameworks extensively while writing programs. In this context, the recommendations provided in code completion pop-ups help developers choose the desired…

Software Engineering · Computer Science 2016-09-01 Andrea Renika D'Souza , Di Yang , Cristina V. Lopes

Machine learning has rapidly advanced the design and discovery of new materials with targeted applications in various systems. First-principles calculations and other computer experiments have been integrated into material design pipelines…

In this paper, we present pomdp_py, a general purpose Partially Observable Markov Decision Process (POMDP) library written in Python and Cython. Existing POMDP libraries often hinder accessibility and efficient prototyping due to the…

Artificial Intelligence · Computer Science 2020-04-22 Kaiyu Zheng , Stefanie Tellex

Pyqcm is a Python/C++ library that implements a few quantum cluster methods with an exact diagonalization impurity solver. Quantum cluster methods are used in the study of strongly correlated electrons to provide an approximate solution to…

Strongly Correlated Electrons · Physics 2024-01-10 Théo N. Dionne , Alexandre Foley , Moïse Rousseau , David Sénéchal

Molecular docking is an essential tool for drug design. It helps the scientist to rapidly know if two molecules, respectively called ligand and receptor, can be combined together to obtain a stable complex. We propose a new multi-objective…

Quantitative Methods · Quantitative Biology 2008-11-05 Jean-Charles Boisson , Laetitia Jourdan , El-Ghazali Talbi , Dragos Horvath

We describe how Python can be leveraged to streamline the curation, modelling and dissemination of drug discovery data as well as the development of innovative, freely available tools for the related scientific community. We look at various…

Other Computer Science · Computer Science 2016-07-05 Michał Nowotka , George Papadatos , Mark Davies , Nathan Dedman , Anne Hersey

Background: Ad hoc parsers are pieces of code that use common string functions like split, trim, or slice to effectively perform parsing. Whether it is handling command-line arguments, reading configuration files, parsing custom file…

Software Engineering · Computer Science 2023-04-20 Michael Schröder , Marc Goritschnig , Jürgen Cito

We introduce Docling, an easy-to-use, self-contained, MIT-licensed, open-source toolkit for document conversion, that can parse several types of popular document formats into a unified, richly structured representation. It is powered by…

$\textit{Pymc-learn}$ is a Python package providing a variety of state-of-the-art probabilistic models for supervised and unsupervised machine learning. It is inspired by $\textit{scikit-learn}$ and focuses on bringing probabilistic machine…

Machine Learning · Statistics 2018-11-05 Daniel Emaasit

High Performance Computing~(HPC) software stacks have become complex, with the dependencies of some applications numbering in the hundreds. Packaging, distributing, and administering software stacks of that scale is a complex undertaking…

Software Engineering · Computer Science 2022-11-14 Farid Zakaria , Thomas R. W. Scogland , Todd Gamblin , Carlos Maltzahn

Smokescreen is an open-source Python library for data-vector concealment (blinding) in cosmological analyses. Data-vector blinding works by applying cosmology-dependent shifts to the observed data vector, moving it away from the true…

Defects are a universal feature of crystalline solids, dictating the key properties and performance of many functional materials. Given their crucial importance yet inherent difficulty in measuring experimentally, computational methods…