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Planning effective interventions in biological systems requires treatment-effect models that adapt to unseen biological contexts by identifying their specific underlying mechanisms. Yet single-cell perturbation datasets span only a handful…

Machine Learning · Computer Science 2026-05-08 Marvin Sextro , Weronika Kłos , Gabriel Dernbach

Quantifying uncertainty in neural networks is a highly relevant problem which is essential to many applications. The two predominant paradigms to tackle this task are Bayesian neural networks (BNNs) and deep ensembles. Despite some…

Machine Learning · Computer Science 2025-01-31 Gabriel Loaiza-Ganem , Valentin Villecroze , Yixin Wang

Learned frame prediction is a current problem of interest in computer vision and video compression. Although several deep network architectures have been proposed for learned frame prediction, to the best of our knowledge, there is no work…

Computer Vision and Pattern Recognition · Computer Science 2021-05-28 M. Akın Yılmaz , A. Murat Tekalp

A very popular model in machine learning is the feedforward neural network (FFN). The FFN can approximate general functions and mitigate the curse of dimensionality. Here we introduce FFNs which represent sections of holomorphic line…

Complex Variables · Mathematics 2021-05-11 Michael R. Douglas

The effectiveness of neural processes (NPs) in modelling posterior prediction maps -- the mapping from data to posterior predictive distributions -- has significantly improved since their inception. This improvement can be attributed to two…

In this work, we aim to establish a Bayesian adaptive learning framework by focusing on estimating latent variables in deep neural network (DNN) models. Latent variables indeed encode both transferable distributional information and…

Audio and Speech Processing · Electrical Eng. & Systems 2024-01-26 Hu Hu , Sabato Marco Siniscalchi , Chin-Hui Lee

Laplace approximations are popular techniques for endowing deep networks with epistemic uncertainty estimates as they can be applied without altering the predictions of the trained network, and they scale to large models and datasets. While…

Machine Learning · Computer Science 2024-11-01 Tristan Cinquin , Marvin Pförtner , Vincent Fortuin , Philipp Hennig , Robert Bamler

We introduce factorize sum split product networks (FSPNs), a new class of probabilistic graphical models (PGMs). FSPNs are designed to overcome the drawbacks of existing PGMs in terms of estimation accuracy and inference efficiency.…

Artificial Intelligence · Computer Science 2020-11-23 Ziniu Wu , Rong Zhu , Andreas Pfadler , Yuxing Han , Jiangneng Li , Zhengping Qian , Kai Zeng , Jingren Zhou

Federated learning (FL for simplification) is a distributed machine learning technique that utilizes global servers and collaborative clients to achieve privacy-preserving global model training without direct data sharing. However,…

Machine Learning · Computer Science 2022-11-28 Mingjia Shi , Yuhao Zhou , Qing Ye , Jiancheng Lv

Tabular classification has traditionally relied on supervised algorithms, which estimate the parameters of a prediction model using its training data. Recently, Prior-Data Fitted Networks (PFNs) such as TabPFN have successfully learned to…

Machine Learning · Computer Science 2023-11-20 Benjamin Feuer , Chinmay Hegde , Niv Cohen

The distribution of the weights of modern deep neural networks (DNNs) - crucial for uncertainty quantification and robustness - is an eminently complex object due to its extremely high dimensionality. This paper proposes one of the first…

Machine Learning · Statistics 2023-10-13 Olivier Laurent , Emanuel Aldea , Gianni Franchi

Isotropic Gaussian priors are the de facto standard for modern Bayesian neural network inference. However, it is unclear whether these priors accurately reflect our true beliefs about the weight distributions or give optimal performance. To…

Deep neural networks (NNs) are powerful black box predictors that have recently achieved impressive performance on a wide spectrum of tasks. Quantifying predictive uncertainty in NNs is a challenging and yet unsolved problem. Bayesian NNs,…

Machine Learning · Statistics 2017-11-07 Balaji Lakshminarayanan , Alexander Pritzel , Charles Blundell

We derive a novel generative model from iterative Gaussian posterior inference. By treating the generated sample as an unknown variable, we can formulate the sampling process in the language of Bayesian probability. Our model uses a…

Machine Learning · Computer Science 2026-01-28 Marten Lienen , Marcel Kollovieh , Stephan Günnemann

While deep neural networks (DNNs) based personalized federated learning (PFL) is demanding for addressing data heterogeneity and shows promising performance, existing methods for federated learning (FL) suffer from efficient systematic…

Machine Learning · Computer Science 2025-05-08 Hui Chen , Hengyu Liu , Zhangkai Wu , Xuhui Fan , Longbing Cao

Inverse problems arise across scientific and engineering domains, where the goal is to infer hidden parameters or physical fields from indirect and noisy observations. Classical approaches, such as variational regularization and Bayesian…

Machine Learning · Statistics 2025-12-03 Ali Mohammad-Djafari , Ning Chu , Li Wang

Bayesian decision theory provides an elegant framework for acting optimally under uncertainty when tractable posterior distributions are available. Modern Bayesian models, however, typically involve intractable posteriors that are…

Machine Learning · Computer Science 2021-06-15 Meet P. Vadera , Soumya Ghosh , Kenney Ng , Benjamin M. Marlin

The global inducing point variational approximation for BNNs is based on using a set of inducing inputs to construct a series of conditional distributions that accurately approximate the conditionals of the true posterior distribution. Our…

Machine Learning · Statistics 2023-10-25 Matthew Ashman , Tommy Rochussen , Adrian Weller

While Bayesian neural networks (BNNs) have drawn increasing attention, their posterior inference remains challenging, due to the high-dimensional and over-parameterized nature. To address this issue, several highly flexible and scalable…

Machine Learning · Statistics 2019-05-10 Ziyu Wang , Tongzheng Ren , Jun Zhu , Bo Zhang

In recent years, neural networks have revolutionized various domains, yet challenges such as hyperparameter tuning and overfitting remain significant hurdles. Bayesian neural networks offer a framework to address these challenges by…

Machine Learning · Computer Science 2025-12-16 Hayk Amirkhanian , Marco F. Huber
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