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The performance of most error-correction algorithms that operate on genomic sequencer reads is dependent on the proper choice of its configuration parameters, such as the value of k in k-mer based techniques. In this work, we target the…
Motivation: Next-generation sequencing tools have enabled producing of huge amount of genomic information at low cost. Unfortunately, presence of sequencing errors in such data affects quality of downstream analyzes. Accuracy of them can be…
Fine-tuning large language models (LLMs) typically relies on producing large sets of input-output pairs. Yet for a given question, there can be many valid outputs. In practice, these outputs are often derived by distilling knowledge from…
DNA sequence alignment involves assigning short DNA reads to the most probable locations on an extensive reference genome. This process is crucial for various genomic analyses, including variant calling, transcriptomics, and epigenomics.…
This paper introduces Exact Linear Attention (ELA), a mechanism that achieves linear computational complexity for Transformer attention by exploiting the exact decomposition property of kernel functions, thereby eliminating approximation…
The third-generation long reads sequencing technologies, such as PacBio and Nanopore, have great advantages over second-generation Illumina sequencing in de novo assembly studies. However, due to the inherent low base accuracy,…
Increasing the input length has been a driver of progress in language modeling with transformers. We identify conditions where shorter inputs are not harmful, and achieve perplexity and efficiency improvements through two new methods that…
Modern Transformer-based models frequently suffer from miscalibration, producing overconfident predictions that do not reflect true empirical frequencies. This work investigates the calibration dynamics of LoRA: Low-Rank Adaptation and a…
Fine-tuning a Pre-trained Language Model (PLM) on a specific downstream task has been a well-known paradigm in Natural Language Processing. However, with the ever-growing size of PLMs, training the entire model on several downstream tasks…
The study of functional genomics--particularly in non-model organisms has been dramatically improved over the last few years by use of transcriptomes and RNAseq. While these studies are potentially extremely powerful, a computationally…
Embedding-based Retrieval Models (ERMs) have emerged as a promising framework for large-scale text retrieval problems due to powerful large language models. Nevertheless, fine-tuning ERMs to reach state-of-the-art results can be expensive…
Cancer detection and prognosis relies heavily on medical imaging, particularly CT and PET scans. Deep Neural Networks (DNNs) have shown promise in tumor segmentation by fusing information from these modalities. However, a critical…
Quantum computing has the potential to solve problems that are intractable for classical systems, yet the high error rates in contemporary quantum devices often exceed tolerable limits for useful algorithm execution. Quantum Error…
Low-Rank Adaptation (LoRA) has emerged as one of the most widely used parameter-efficient fine-tuning (PEFT) methods for adapting large language models (LLMs) to downstream tasks. While highly effective in single-task settings, it struggles…
Recently Transformers have provided state-of-the-art performance in sparse matching, crucial to realize high-performance 3D vision applications. Yet, these Transformers lack efficiency due to the quadratic computational complexity of their…
Transformer models are computationally costly on long sequences since regular attention has quadratic $O(n^2)$ time complexity. We introduce Wavelet-Enhanced Random Spectral Attention (WERSA), a novel mechanism of linear $O(n)$ time…
Quantum Error Correction (QEC) is one of the fundamental problems in quantum computer systems, which aims to detect and correct errors in the data qubits within quantum computers. Due to the presence of unreliable data qubits in existing…
Click-Through Rate (CTR) prediction holds a paramount position in recommender systems. The prevailing ID-based paradigm underperforms in cold-start scenarios due to the skewed distribution of feature frequency. Additionally, the utilization…
Transformers are considered one of the most important deep learning models since 2018, in part because it establishes state-of-the-art (SOTA) records and could potentially replace existing Deep Neural Networks (DNNs). Despite the remarkable…
Transformer-based large language models (LLMs) excel in modeling complex language patterns but face significant computational costs during inference, especially with long inputs due to the attention mechanism's memory overhead. We observe…