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The Multiple Instance Learning (MIL) paradigm is attracting plenty of attention in medical imaging classification, where labeled data is scarce. MIL methods cast medical images as bags of instances (e.g. patches in whole slide images, or…

Computer Vision and Pattern Recognition · Computer Science 2025-07-22 Francisco M. Castro-Macías , Pablo Morales-Álvarez , Yunan Wu , Rafael Molina , Aggelos K. Katsaggelos

Histopathological images provide rich information for disease diagnosis. Large numbers of histopathological images have been digitized into high resolution whole slide images, opening opportunities in developing computational image analysis…

Image and Video Processing · Electrical Eng. & Systems 2020-11-06 Jiayun Li , Wenyuan Li , Anthony Sisk , Huihui Ye , W. Dean Wallace , William Speier , Corey W. Arnold

In healthcare, it is essential to explain the decision-making process of machine learning models to establish the trustworthiness of clinicians. This paper introduces BI-RADS-Net, a novel explainable deep learning approach for cancer…

Computer Vision and Pattern Recognition · Computer Science 2021-10-11 Boyu Zhang , Aleksandar Vakanski , Min Xian

In many histopathology tasks, sample classification depends on morphological details in tissue or single cells that are only visible at the highest magnification. For a pathologist, this implies tedious zooming in and out, while for a…

Computer Vision and Pattern Recognition · Computer Science 2023-03-03 Ario Sadafi , Nassir Navab , Carsten Marr

This article describes the clinical validation study setup, statistical analysis and results for a deep learning algorithm which detects dental anomalies in intraoral radiographic images, more specifically caries, apical lesions, root canal…

Image and Video Processing · Electrical Eng. & Systems 2024-02-23 Pieter Van Leemput , Johannes Keustermans , Wouter Mollemans

In this paper, we propose a new image instance segmentation method that segments individual glands (instances) in colon histology images. This is a task called instance segmentation that has recently become increasingly important. The…

Computer Vision and Pattern Recognition · Computer Science 2016-07-15 Yan Xu , Yang Li , Mingyuan Liu , Yipei Wang , Maode Lai , Eric I-Chao Chang

Endoscopy serves as an essential procedure for evaluating the gastrointestinal (GI) tract and plays a pivotal role in identifying GI-related disorders. Recent advancements in deep learning have demonstrated substantial progress in detecting…

Computer Vision and Pattern Recognition · Computer Science 2025-03-04 Astitva Kamble , Vani Bandodkar , Saakshi Dharmadhikary , Veena Anand , Pradyut Kumar Sanki , Mei X. Wu , Biswabandhu Jana

Objective: A new image instance segmentation method is proposed to segment individual glands (instances) in colon histology images. This process is challenging since the glands not only need to be segmented from a complex background, they…

Computer Vision and Pattern Recognition · Computer Science 2017-11-27 Yan Xu , Yang Li , Yipei Wang , Mingyuan Liu , Yubo Fan , Maode Lai , Eric I-Chao Chang

A key issue in critical contexts such as medical diagnosis is the interpretability of the deep learning models adopted in decision-making systems. Research in eXplainable Artificial Intelligence (XAI) is trying to solve this issue. However,…

Computer Vision and Pattern Recognition · Computer Science 2021-11-24 Carlo Metta , Andrea Beretta , Riccardo Guidotti , Yuan Yin , Patrick Gallinari , Salvatore Rinzivillo , Fosca Giannotti

When we deploy machine learning models in high-stakes medical settings, we must ensure these models make accurate predictions that are consistent with known medical science. Inherently interpretable networks address this need by explaining…

Computer Vision and Pattern Recognition · Computer Science 2021-10-06 Alina Jade Barnett , Fides Regina Schwartz , Chaofan Tao , Chaofan Chen , Yinhao Ren , Joseph Y. Lo , Cynthia Rudin

Unlike other histology analysis, classification of tubule status in testis histology is very challenging due to their high similarity of texture and shape. Traditional deep learning networks have difficulties to capture nuance details among…

Computer Vision and Pattern Recognition · Computer Science 2017-07-20 Chia-Yu Kao , Leonard McMillan

Recent advances in attention-based multiple instance learning (MIL) have improved our insights into the tissue regions that models rely on to make predictions in digital pathology. However, the interpretability of these approaches is still…

Quantitative Methods · Quantitative Biology 2023-09-11 Willem Bonnaffé , CRUK ICGC Prostate Group , Freddie Hamdy , Yang Hu , Ian Mills , Jens Rittscher , Clare Verrill , Dan J. Woodcock

The identification and quantification of markers in medical images is critical for diagnosis, prognosis and management of patients in clinical practice. Supervised- or weakly supervised training enables the detection of findings that are…

The computer-aided analysis of medical scans is a longstanding goal in the medical imaging field. Currently, deep learning has became a dominant methodology for supporting pathologists and radiologist. Deep learning algorithms have been…

Machine Learning · Computer Science 2017-12-06 Jakub M. Tomczak , Maximilian Ilse , Max Welling

Accurate segmentation of tissue in histopathological images can be very beneficial for defining regions of interest (ROI) for streamline of diagnostic and prognostic tasks. Still, adapting to different domains is essential for…

Image and Video Processing · Electrical Eng. & Systems 2023-03-10 Saul Fuster , Farbod Khoraminia , Trygve Eftestøl , Tahlita C. M. Zuiverloon , Kjersti Engan

Interpretability in machine learning models is important in high-stakes decisions, such as whether to order a biopsy based on a mammographic exam. Mammography poses important challenges that are not present in other computer vision tasks:…

Machine Learning · Computer Science 2021-03-24 Alina Jade Barnett , Fides Regina Schwartz , Chaofan Tao , Chaofan Chen , Yinhao Ren , Joseph Y. Lo , Cynthia Rudin

Deep neural network models have been proven to be very successful in image classification tasks, also for medical diagnosis, but their main concern is its lack of interpretability. They use to work as intuition machines with high…

Machine Learning · Computer Science 2019-04-26 Jordi de la Torre , Aida Valls , Domenec Puig

Automated dermoscopic image analysis has witnessed rapid growth in diagnostic performance. Yet adoption faces resistance, in part, because no evidence is provided to support decisions. In this work, an approach for evidence-based…

Computer Vision and Pattern Recognition · Computer Science 2018-08-03 Noel C. F. Codella , Chung-Ching Lin , Allan Halpern , Michael Hind , Rogerio Feris , John R. Smith

Artificial intelligence (AI) technology is increasingly used for digital orthodontics, but one of the challenges is to automatically and accurately detect tooth landmarks and axes. This is partly because of sophisticated geometric…

Image and Video Processing · Electrical Eng. & Systems 2021-11-10 Guangshun Wei , Zhiming Cui , Jie Zhu , Lei Yang , Yuanfeng Zhou , Pradeep Singh , Min Gu , Wenping Wang

This paper proposed a cutting-edge multiclass teeth segmentation architecture that integrates an M-Net-like structure with Swin Transformers and a novel component named Teeth Attention Block (TAB). Existing teeth image segmentation methods…

Computer Vision and Pattern Recognition · Computer Science 2023-11-09 Afnan Ghafoor , Seong-Yong Moon , Bumshik Lee