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We present a new data-driven model to reconstruct nonlinear flow from spatially sparse observations. The model is a version of a conditional variational auto-encoder (CVAE), which allows for probabilistic reconstruction and thus uncertainty…

Machine Learning · Statistics 2021-02-24 Kristian Gundersen , Anna Oleynik , Nello Blaser , Guttorm Alendal

Retrosynthetic planning aims to devise a complete multi-step synthetic route from starting materials to a target molecule. Current strategies use a decoupled approach of single-step retrosynthesis models and search algorithms, taking only…

Machine Learning · Computer Science 2023-06-01 Songtao Liu , Zhengkai Tu , Minkai Xu , Zuobai Zhang , Lu Lin , Rex Ying , Jian Tang , Peilin Zhao , Dinghao Wu

Machine learning models are poised to make a transformative impact on chemical sciences by dramatically accelerating computational algorithms and amplifying insights available from computational chemistry methods. However, achieving this…

Large language models (LLMs) offer new opportunities for automated data extraction and property prediction across materials science, yet their use in superconductivity research remains limited. Here we construct a large experimental…

Materials Science · Physics 2025-12-12 Suman Itani , Yibo Zhang , Ranjit Itani , Jiadong Zang

Computer-assisted synthesis planning aims to help chemists find better reaction pathways faster. Finding viable and short pathways from sugar molecules to value-added chemicals can be modeled as a retrosynthesis planning problem with a…

Other Computer Science · Computer Science 2019-11-19 Peihong Jiang , Hieu Doan , Sandeep Madireddy , Rajeev Surendran Assary , Prasanna Balaprakash

This work introduces a comprehensive approach utilizing data-driven methods to elucidate the deposition process regimes in Chemical Vapor Deposition (CVD) reactors and the interplay of physical mechanism that dominate in each one of them.…

Variational autoencoder (VAE) neural networks can be trained to generate power system states that capture both marginal distribution and multivariate dependencies of historical data. The coordinates of the latent space codes of VAEs have…

Systems and Control · Electrical Eng. & Systems 2023-03-22 Chenguang Wang , Ensieh Sharifnia , Simon H. Tindemans , Peter Palensky

This thesis develops methods for causal inference and causal representation learning (CRL) in high-dimensional, time-varying data. The first contribution introduces the Causal Dynamic Variational Autoencoder (CDVAE), a model for estimating…

Machine Learning · Statistics 2025-12-05 Mouad EL Bouchattaoui

Our goal is to recover time-delayed latent causal variables and identify their relations from measured temporal data. Estimating causally-related latent variables from observations is particularly challenging as the latent variables are not…

Machine Learning · Statistics 2022-02-10 Weiran Yao , Yuewen Sun , Alex Ho , Changyin Sun , Kun Zhang

The ability to accurately model random fields plays a critical role in science and engineering for problems involving uncertain, spatially-varying quantities such as heterogeneous material properties and turbulent flows. Deep generative…

Biochemical reactions inside living cells often occur in the presence of crowders -- molecules that do not participate in the reactions but influence the reaction rates through excluded volume effects. However the standard approach to…

Quantitative Methods · Quantitative Biology 2022-05-16 Svitlana Braichenko , Ramon Grima , Guido Sanguinetti

Designing new industrial materials with desired properties can be very expensive and time consuming. The main difficulty is to generate compounds that correspond to realistic materials. Indeed, the description of compounds as vectors of…

Machine Learning · Computer Science 2021-12-20 Fouad Oubari , Antoine de Mathelin , Rodrigue Décatoire , Mathilde Mougeot

Disentangled representation learning aims to learn low-dimensional representations where each dimension corresponds to an underlying generative factor. While the Variational Auto-Encoder (VAE) is widely used for this purpose, most existing…

Machine Learning · Computer Science 2024-12-31 Di Fan , Yannian Kou , Chuanhou Gao

Long-term chemical durability of glass, crucial for immobilizing nuclear waste, is governed by glass properties such as composition, surface geometry, as well as external factors like thermodynamic conditions and surrounding medium. Despite…

Deep generative models have recently emerged as a promising de novo drug design method. In this respect, deep generative conditional variational autoencoder (CVAE) models are a powerful approach for generating novel molecules with desired…

Machine Learning · Computer Science 2023-08-21 Guang Jun Nicholas Ang , De Tao Irwin Chin , Bingquan Shen

A combined autoencoder (AE) and neural ordinary differential equation (NODE) framework has been used as a data-driven reduced-order model for time integration of a stiff reacting system. In this study, a new loss term using a latent…

Computational Physics · Physics 2026-03-18 Mert Yakup Baykan , Vijayamanikandan Vijayarangan , Dong-hyuk Shin , Hong G. Im

This paper addresses imitation learning for motion prediction problem in autonomous driving, especially in multi-agent setting. Different from previous methods based on GAN, we present the conditional latent ordinary differential equation…

Robotics · Computer Science 2024-05-30 Khang Truong Giang , Yongjae Kim , Andrea Finazzi

Recent advances in deep learning generative models (GMs) have created high capabilities in accessing and assessing complex high-dimensional data, allowing superior efficiency in navigating vast material configuration space in search of…

Materials Science · Physics 2024-11-13 Xiaoshan Luo , Zhenyu Wang , Pengyue Gao , Jian Lv , Yanchao Wang , Changfeng Chen , Yanming Ma

Artificial intelligence (AI) is transforming materials science, enabling both theoretical advancements and accelerated materials discovery. Recent progress in crystal generation models, which design crystal structures for targeted…

Materials Science · Physics 2025-02-25 Zhuoyuan Li , Siyu Liu , Beilin Ye , David J. Srolovitz , Tongqi Wen

Learning generative models that span multiple data modalities, such as vision and language, is often motivated by the desire to learn more useful, generalisable representations that faithfully capture common underlying factors between the…

Machine Learning · Statistics 2019-11-11 Yuge Shi , N. Siddharth , Brooks Paige , Philip H. S. Torr
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