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Most modern probabilistic generative models, such as the variational autoencoder (VAE), have certain indeterminacies that are unresolvable even with an infinite amount of data. Different tasks tolerate different indeterminacies, however…

Machine Learning · Statistics 2023-03-06 Quanhan Xi , Benjamin Bloem-Reddy

Generative models based on generative adversarial networks (GANs) and variational autoencoders (VAEs) have been widely studied in the fields of image generation, speech generation, and drug discovery, but, only a few studies have focused on…

Machine Learning · Computer Science 2019-10-28 Yoshihide Sawada , Koji Morikawa , Mikiya Fujii

Deep generative models like GAN and VAE have shown impressive results in generating unconstrained objects like images. However, many design settings arising in industrial design, material science, computer graphics and more require that the…

Machine Learning · Computer Science 2024-06-07 Aaron Ferber , Arman Zharmagambetov , Taoan Huang , Bistra Dilkina , Yuandong Tian

Variational auto-encoders (VAEs) provide an attractive solution to image generation problem. However, they tend to produce blurred and over-smoothed images due to their dependence on pixel-wise reconstruction loss. This paper introduces a…

Computer Vision and Pattern Recognition · Computer Science 2018-04-30 Salman H. Khan , Munawar Hayat , Nick Barnes

Probabilistic generative models are attractive for scientific modeling because their inferred parameters can be used to generate hypotheses and design experiments. This requires that the learned model provide an accurate representation of…

Machine Learning · Statistics 2023-01-18 Liyun Tu , Austin Talbot , Neil Gallagher , David Carlson

The ability to accurately model random fields plays a critical role in science and engineering for problems involving uncertain, spatially-varying quantities such as heterogeneous material properties and turbulent flows. Deep generative…

Generative modelling of multi-user datasets has become prominent in science and engineering. Generating a data point for a given user requires employing user information, and conventional generative models, including variational…

Machine Learning · Computer Science 2026-05-19 Kutay Bölat , Simon Tindemans

Although variational autoencoders (VAEs) represent a widely influential deep generative model, many aspects of the underlying energy function remain poorly understood. In particular, it is commonly believed that Gaussian encoder/decoder…

Machine Learning · Computer Science 2019-10-31 Bin Dai , David Wipf

Conditional discrete generative models struggle to faithfully compose multiple input conditions. To address this, we derive a theoretically-grounded formulation for composing discrete probabilistic generative processes, with masked…

Machine Learning · Computer Science 2026-04-08 Jamie Stirling , Noura Al-Moubayed , Chris G. Willcocks , Hubert P. H. Shum

Conditional discrete generative models struggle to faithfully compose multiple input conditions. To address this, we derive a theoretically-grounded formulation for composing discrete probabilistic generative processes, with masked…

Computer Vision and Pattern Recognition · Computer Science 2026-04-08 Jamie Stirling , Noura Al-Moubayed , Chris G. Willcocks , Hubert P. H. Shum

Recently, molecule generation using deep learning has been actively investigated in drug discovery. In this field, Transformer and VAE are widely used as powerful models, but they are rarely used in combination due to structural and…

Biomolecules · Quantitative Biology 2024-04-08 Yasuhiro Yoshikai , Tadahaya Mizuno , Shumpei Nemoto , Hiroyuki Kusuhara

The variational autoencoder (VAE) framework remains a popular option for training unsupervised generative models, especially for discrete data where generative adversarial networks (GANs) require workaround to create gradient for the…

Machine Learning · Computer Science 2019-04-24 Jason Chou , Gautam Hathi

Layout design with complex constraints is a challenging problem to solve due to the non-uniqueness of the solution and the difficulties in incorporating the constraints into the conventional optimization-based methods. In this paper, we…

Signal Processing · Electrical Eng. & Systems 2018-06-11 Yujie Zhang , Wenjing Ye

Laminated composite materials are widely used in most fields of engineering. Wave propagation analysis plays an essential role in understanding the short-duration transient response of composite structures. The forward physics-based models…

Signal Processing · Electrical Eng. & Systems 2022-12-14 Mahindra Rautela , J. Senthilnath , Armin Huber , S. Gopalakrishnan

The estimation of patient-specific tissue properties in the form of model parameters is important for personalized physiological models. However, these tissue properties are spatially varying across the underlying anatomical model,…

Machine Learning · Statistics 2020-05-19 Jwala Dhamala , Sandesh Ghimire , John L. Sapp , B. Milan Horácek , Linwei Wang

We develop VSD, a method for conditioning a generative model of discrete, combinatorial designs on a rare desired class by efficiently evaluating a black-box (e.g. experiment, simulation) in a batch sequential manner. We call this task…

Machine Learning · Statistics 2025-11-24 Daniel M. Steinberg , Rafael Oliveira , Cheng Soon Ong , Edwin V. Bonilla

The rise of deep learning applications in the fashion industry has fueled advances in curating large-scale datasets to build applications for product design, image retrieval, and recommender systems. In this paper, the author proposes using…

Computer Vision and Pattern Recognition · Computer Science 2020-09-03 James-Andrew Sarmiento

The synthesis of product design concepts stands at the crux of early-phase development processes for technical products, traditionally posing an intricate interdisciplinary challenge. The application of deep learning methods, particularly…

Machine Learning · Computer Science 2025-05-22 Phillip Mueller , Lars Mikelsons

In this paper, we investigate the problem of string-based molecular generation via variational autoencoders (VAEs) that have served a popular generative approach for various tasks in artificial intelligence. We propose a simple, yet…

Machine Learning · Computer Science 2022-08-24 Kisoo Kwon , Kuhwan Jung , Junghyun Park , Hwidong Na , Jinwoo Shin

While cloud-resolving models can explicitly simulate the details of small-scale storm formation and morphology, these details are often ignored by climate models for lack of computational resources. Here, we explore the potential of…

Atmospheric and Oceanic Physics · Physics 2020-10-27 Griffin Mooers , Jens Tuyls , Stephan Mandt , Michael Pritchard , Tom Beucler