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Adaptive Radiation Therapy (ART) was developed based on Image-guided Radiation Therapy (IGRT) and it is the trend of photon radiation therapy. To get a better use of Cone Beam CT (CBCT) images for ART, the CBCT system model was established…

Medical Physics · Physics 2014-08-21 Yu Wang , Chaobin Chen , Ruifen Cao , Liqin Hu , Bingbing Li

Correcting scan-positional errors is critical in achieving electron ptychography with both high resolution and high precision. This is a demanding and challenging task due to the sheer number of parameters that need to be optimized. For…

Other Condensed Matter · Physics 2022-11-08 Shoucong Ning , Wenhui Xu , Leyi Loh , Zhen Lu , Michel Bosman , Fucai Zhang , Qian He

The work seeks to develop an algorithm for image reconstruction by directly inverting the non-linear data model in spectral CT. Using the non-linear data model, we formulate the image-reconstruction problem as a non-convex optimization…

Medical Physics · Physics 2021-02-23 Buxin Chen , Zheng Zhang , Dan Xia , Emil Y. Sidky , Xiaochuan Pan

Bolton and Schlegel presented a promising deconvolution method to extract 1D spectra from a 2D optical fiber spectral CCD image. The method could eliminate the PSF difference between fibers, extract spectra to the photo noise level, as well…

Instrumentation and Methods for Astrophysics · Physics 2015-06-24 Guangwei Li , Haotong Zhang , Zhongrui Bai

Cone-beam CT (CBCT) provides on-board volumetric anatomy for image guidance and treatment adaptation in radiotherapy. To compensate for respiration-induced anatomical motion, time-resolved CBCT is highly desired to capture the…

Medical Physics · Physics 2025-11-05 Ruizhi Zuo , Hua-Chieh Shao , You Zhang

In radiation therapy (RT), the reliance on pre-treatment computed tomography (CT) images encounter challenges due to anatomical changes, necessitating adaptive planning. Daily cone-beam CT (CBCT) imaging, pivotal for therapy adjustment,…

Computer Vision and Pattern Recognition · Computer Science 2024-09-20 Joonil Hwang , Sangjoon Park , NaHyeon Park , Seungryong Cho , Jin Sung Kim

One of the advantages of spectral computed tomography (CT) is it can achieve accurate material components using the material decomposition methods. The image-based material decomposition is a common method to obtain specific material…

Image and Video Processing · Electrical Eng. & Systems 2019-10-18 Weiwen Wu , Peijun Chen , Vince Vardhanabhuti , Weifei Wu , Hengyong Yu

Purpose: Fast kV-switching (FKS) and dual-layer flat-panel detector (DL-FPD) technologies have been actively studied as promising dual-energy solutions for FPD-based cone-beam computed tomography (CBCT). However, CBCT spectral imaging is…

Medical Physics · Physics 2024-01-03 Hao Zhou , Li Zhang , Zhilei Wang , Hewei Gao

CT images have been used to generate radiation therapy treatment plans for more than two decades. Dual-energy CT (DECT) has shown high accuracy in estimating electronic density or proton stopping-power maps used in treatment planning.…

Image and Video Processing · Electrical Eng. & Systems 2022-02-02 Tao Ge , Maria Medrano , Rui Liao , Jeffrey F. Williamson , David G. Politte , Bruce R. Whiting , Joseph A. O'Sullivan

3D Cone-Beam CT (CBCT) is widely used in radiotherapy but suffers from motion artifacts due to breathing. A common clinical approach mitigates this by sorting projections into respiratory phases and reconstructing images per phase, but this…

Image and Video Processing · Electrical Eng. & Systems 2025-06-30 Yuliang Huang , Imraj Singh , Thomas Joyce , Kris Thielemans , Jamie R. McClelland

We introduce a new CT image reconstruction algorithm that is less affected by various artifacts. The new reconstruction algorithm is a method of minimizing the difference between synchrotron X-ray tomography data and sinograms generated…

Medical Physics · Physics 2021-11-22 Byung Chun Kim , Hyunju Lee , Kyungtaek Jun

Iodinated contrast media is essential for dual-energy computed tomography (DECT) angiography. Previous studies show that iodinated contrast media may cause side effects, and the interruption of the supply chain in 2022 led to a severe…

Image and Video Processing · Electrical Eng. & Systems 2023-08-28 Qing Lyu , Josh Tan , Megan E. Lipford , Chuang Niu , Micheal E. Zapadka , Christopher M. Lack , Jonathan D. Clemente , Christopher T. Whitlow , Ge Wang

Combining dual-energy computed tomography (DECT) with positron emission tomography (PET) offers many potential clinical applications but typically requires expensive hardware upgrades or increases radiation doses on PET/CT scanners due to…

Medical Physics · Physics 2024-06-21 Siqi Li , Yansong Zhu , Benjamin A. Spencer , Guobao Wang

Background: Cone-beam computed tomography (CBCT) scans, performed fractionally (e.g., daily or weekly), are widely utilized for patient alignment in the image-guided radiotherapy (IGRT) process, thereby making it a potential imaging…

We present a new method for image reconstruction which replaces the projector in a projected gradient descent (PGD) with a convolutional neural network (CNN). CNNs trained as high-dimensional (image-to-image) regressors have recently been…

Computer Vision and Pattern Recognition · Computer Science 2018-09-11 Harshit Gupta , Kyong Hwan Jin , Ha Q. Nguyen , Michael T. McCann , Michael Unser

Spectral CT has great potential for a variety of clinical applications due to the improved material discrimination with respect to conventional CT. Many clinical and preclinical spectral CT systems have two spectral channels for dual-energy…

Medical Physics · Physics 2020-10-17 Matthew Tivnan , Wenying Wang , J. Webster Stayman

Dual spectral computed tomography (DSCT) can achieve energy- and material-selective images, and has a superior distinguishability of some materials than conventional single spectral computed tomography (SSCT). However, the decomposition…

Optimization and Control · Mathematics 2017-11-22 Qian Wang

Computed tomography (CT) involves a patient's exposure to ionizing radiation. To reduce the radiation dose, we can either lower the X-ray photon count or down-sample projection views. However, either of the ways often compromises image…

Image and Video Processing · Electrical Eng. & Systems 2023-10-12 Wenjun Xia , Yongyi Shi , Chuang Niu , Wenxiang Cong , Ge Wang

Dual-energy computed tomography (DECT) has been widely used to obtain quantitative elemental composition of imaged subjects for personalized and precise medical diagnosis. Compared with existing high-end DECT leveraging advanced X-ray…

Medical Physics · Physics 2024-08-13 Qiaoxin Li , Dong Liang , Yinsheng Li

Many spectral CT applications require accurate material decomposition. Existing material decomposition algorithms are often susceptible to significant noise magnification or, in the case of one-step model-based approaches, hampered by slow…

Medical Physics · Physics 2025-07-22 Xiao Jiang , Grace J. Gang , J. Webster Stayman