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Fine-tuning pre-trained models on targeted datasets enhances task-specific performance but often comes at the expense of generalization. Model merging techniques, which integrate multiple fine-tuned models into a single multi-task model…

Machine Learning · Computer Science 2025-09-11 Zitao Fang , Guodong DU , Shuyang Yu , Yifei Guo , Yiwei Zhang , Yiyao Cao , Jing Li , Ho-Kin Tang , Sim Kuan Goh

The resurgence of autonomous agents built using large language models (LLMs) to solve complex real-world tasks has brought increased focus on LLMs' fundamental ability of tool or function calling. At the core of these agents, an LLM must…

Cloud computing recently developed into a viable alternative to on-premises systems for executing high-performance computing (HPC) applications. With the emergence of new vendors and hardware options, there is now a growing need to…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-12-14 Mohammad Mohammadi , Timur Bazhirov

Contemporary modeling approaches to the dynamics of neural networks consider two main classes of models: biologically grounded spiking neurons and functionally inspired rate-based units. The unified simulation framework presented here…

Neurons and Cognition · Quantitative Biology 2017-11-27 Jan Hahne , David Dahmen , Jannis Schuecker , Andreas Frommer , Matthias Bolten , Moritz Helias , Markus Diesmann

A computational workflow, also known as workflow, consists of tasks that must be executed in a specific order to attain a specific goal. Often, in fields such as biology, chemistry, physics, and data science, among others, these workflows…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-06-14 George Papadimitriou , Hongwei Jin , Cong Wang , Rajiv Mayani , Krishnan Raghavan , Anirban Mandal , Prasanna Balaprakash , Ewa Deelman

Simulating fluid flow around arbitrary shapes is key to solving various engineering problems. However, simulating flow physics across complex geometries remains numerically challenging and computationally resource-intensive, particularly…

A key element of the European Union's Human Brain Project (HBP) and other large-scale brain research projects is simulation of large-scale model networks of neurons. Here we argue why such simulations will likely be indispensable for…

Predicting the evolution of complex physical systems remains a central problem in science and engineering. Despite rapid progress in scientific Machine Learning (ML) models, a critical bottleneck is the lack of expensive real-world data,…

We introduce a machine-learning (ML) framework for high-throughput benchmarking of diverse representations of chemical systems against datasets of materials and molecules. The guiding principle underlying the benchmarking approach is to…

Machine Learning · Computer Science 2021-12-07 Carl Poelking , Felix A. Faber , Bingqing Cheng

It is common to evaluate the performance of a machine learning model by measuring its predictive power on a test dataset. This approach favors complicated models that can smoothly fit complex functions and generalize well from training data…

Machine Learning · Computer Science 2022-10-07 Hugo Cisneros , Josef Sivic , Tomas Mikolov

Behavioral models are the key enablers for behavioral analysis of Software Product Lines (SPL), including testing and model checking. Active model learning comes to the rescue when family behavioral models are non-existent or outdated. A…

Software Engineering · Computer Science 2022-03-11 Shaghayegh Tavassoli , Carlos Diego Nascimento Damasceno , Mohammad Reza Mousavi , Ramtin Khosravi

We present a multi-scale differentiable brain modeling workflow utilizing BrainPy, a unique differentiable brain simulator that combines accurate brain simulation with powerful gradient-based optimization. We leverage this capability of…

Neural and Evolutionary Computing · Computer Science 2024-09-26 Chaoming Wang , Muyang Lyu , Tianqiu Zhang , Sichao He , Si Wu

The Memory stress (Mess) framework provides a unified view of the memory system benchmarking, simulation and application profiling. The Mess benchmark provides a holistic and detailed memory system characterization. It is based on hundreds…

Simulation code for conventional supercomputers serves as a reference for neuromorphic computing systems. The present bottleneck of distributed large-scale spiking neuronal network simulations is the communication between compute nodes.…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-02-27 Melissa Lober , Markus Diesmann , Susanne Kunkel

Open-source simulation tools play a crucial role for neuromorphic application engineers and hardware architects to investigate performance bottlenecks and explore design optimizations before committing to silicon. Reconfigurable…

Emerging Technologies · Computer Science 2024-04-26 Sahil Hassan , Michael Inouye , Miguel C. Gonzalez , Ilkin Aliyev , Joshua Mack , Maisha Hafiz , Ali Akoglu

Running scientific workflows on a supercomputer can be a daunting task for a scientific domain specialist. Workflow management solutions (WMS) are a standard method for reducing the complexity of application deployment on high performance…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-07-30 Wouter Klijn , Sandra Diaz-Pier , Abigail Morrison , Alexander Peyser

For scientific software, especially those used for large-scale simulations, achieving good performance and efficiently using the available hardware resources is essential. It is important to regularly perform benchmarks to ensure the…

Neuroscience models commonly have a high number of degrees of freedom and only specific regions within the parameter space are able to produce dynamics of interest. This makes the development of tools and strategies to efficiently find…

Rising computational demands of modern natural language processing (NLP) systems have increased the barrier to entry for cutting-edge research while posing serious environmental concerns. Yet, progress on model efficiency has been impeded…

Recent advancements in data stream processing frameworks have improved real-time data handling, however, scalability remains a significant challenge affecting throughput and latency. While studies have explored this issue on local machines…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-04-04 Apurv Deepak Kulkarni , Siavash Ghiasvand