Related papers: Positronium imaging with the novel multiphoton PET…
Positron emission tomography (PET) is a medical imaging method based on the measurement of concentrations of positron-emitting radionuclides in a living body. In the PET imaging system, glucose is labeled with a positron-emitting…
Samples of uterine leiomyomatis and normal tissues taken from patients after surgery were investigated using the Positron Annihilation Lifetime Spectroscopy (PALS). Significant differences in all PALS parameters between normal and diseased…
Objective: Positron Emission Tomography (PET) has been a commonly used imaging modality in broad clinical applications. One of the most important tradeoffs in PET imaging is between image quality and radiation dose: high image quality comes…
Positronium and Muonium are purely leptonic atoms and hence free of an internal sub-structure. This qualifies them as potentially well suited systems to probe the existence of physics beyond the Standard Model. We hence carry out a…
Time-of-Flight Positron Emission Tomography is a medical imaging technique, based on the detection of two back-to-back {\gamma}-photons generated from radiotracers injected in the body. Its limit is the ability of employed scintillation…
We report the first observation of the annihilation of positronium from the 2S state. Positronium (Ps) is excited with a two-photon transition from the 1S to the 2S state where its lifetime is increased by a factor of eight compared to the…
Currently inorganic scintillator detectors are used in all commercial Time of Flight Positron Emission Tomograph (TOF-PET) devices. The J-PET collaboration investigates a possibility of construction of a PET scanner from plastic…
Objective: This study aims to develop and validate a novel framework, iPhantom, for automated creation of patient-specific phantoms or digital-twins (DT) using patient medical images. The framework is applied to assess radiation dose to…
Positron Emission Mammography imaging system (PEMi) is a nuclear medicine diagnosis method dedicated for breast imaging. It provides a better resolution in detection of millimeter-sized breast tumors than whole-body PET. To address the…
Positron emission tomography (PET) provides molecular biomarkers for Alzheimer's disease and related dementias (ADRD) and is increasingly used for diagnosis, staging, and clinical trial enrichment. However, its use is limited by cost,…
This paper reviewed the machine learning-based studies for quantitative positron emission tomography (PET). Specifically, we summarized the recent developments of machine learning-based methods in PET attenuation correction and low-count…
Low-resolution and signal-dependent noise distribution in positron emission tomography (PET) images makes denoising process an inevitable step prior to qualitative and quantitative image analysis tasks. Conventional PET denoising methods…
A major strength of iterative algorithms used in positron emission tomography (PET) lies in their abilities to introduce precise models of the physics at play, which includes the statistical nature of the detection processes, and a detailed…
Ion beam therapy has become a frequently applied form of cancer therapy over the last years. The advantage of ion beam therapy over conventional radiotherapy using photons is the strongly localized dose deposition, leading to a reduction of…
Recent advances in high-resolution biomedical imaging focusing on morphological, electrical, and biochemical properties of cells and tissues, scaling from cell clusters down to the molecular level, have improved cancer diagnosis. Multiscale…
The growing interest in human-grade total body positron emission tomography (PET) systems has also application in small animal research. Due to the existing limitations in human-based studies involving drug development and novel treatment…
PET imaging is an invaluable tool in clinical settings as it captures the functional activity of both healthy anatomy and cancerous lesions. Developing automatic lesion segmentation methods for PET images is crucial since manual lesion…
This manuscript introduces a novel method to assess tissue oxygen concentration via the quantum entanglement (QE) of photons originating from positronium which is produced within the patient's body during positron emission tomography. We…
Purpose: To demonstrate a proton imaging system based on well-established fast scintillator technology to achieve high performance with low cost and complexity, with the potential of a straightforward translation into clinical use. Methods:…
We present the current status of our project of developing a photon counting detector for medical imaging. An example motivation lays in producing a monitoring and dosimetry device for boron neutron capture therapy, currently not…