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The benefits of ultrasound are its ease-of-use and its ability to precisely deliver energy in opaque and complex media. However, most materials responsive to ultrasound show a weak response, requiring the use of high powers, which are…
Intracellular delivery of biomolecules remains a critical challenge in both basic cell biology and translational therapeutics. We introduce Programmable Acoustic Standing-wave Transfection (PAST), a microfluidic tool that leverages…
Significant reduction in target strength and radiation signature can be achieved by surrounding an object with multiple concentric layers comprised of three acoustic fluids. The idea is to make a finely layered shell with the thickness of…
Despite decades of research and development, the optimal efficiency of slurry-packed HPLC columns is still hindered by inherent long-range flow heterogeneity from the wall to the central bulk region of these columns. Here, we show an…
Data from Direct Numerical Simulations of disperse bubbly flows in a vertical channel are used to study the effect of the bubbles on the carrier-phase turbulence. A new method is developed, based on the barycentric map approach, that allows…
It has been conjectured by Bagnold [1] that an assembly of hard non-deformable spheres could behave as a compressible medium when slowly sheared, as the average density of such a system effectively depends on the confining pressure. Here we…
Particle migration and trapping in ultrasonically actuated microscale flows arise from the competition between acoustic radiation forces and streaming-induced drag. While these mechanisms are well understood in Newtonian fluids, the role of…
Understanding the dynamics of instabilities along fluid-solid interfaces is critical for the efficacy of focused ultrasound therapy tools (e.g., histotripsy) and microcavitation rheometry techniques. Non-uniform pressure fields generated by…
Control of bubble motion is essential for improving efficiency and creating new functionalities in electrochemistry, heat transfer, and biomedical systems. Photoresponsive surfactants enable bubble manipulation by creating surface tension…
We study experimentally the motion of non-deformable microbeads in a linear shear flow close to a wall bearing a thin and soft polymer layer. Combining microfluidics and 3D optical tracking, we demonstrate that the steady-state bead/surface…
Acoustic streaming is studied in a rectangular microfluidic channel. It is demonstrated theoretically, numerically, and experimentally with good agreement, frictional heating can alter the streaming pattern qualitatively at high acoustic…
The nonlinear dynamic behaviour of microscopic bubbles near a wall is investigated. The Keller-Miksis-Parlitz equation is adopted, but modified to account for the presence of the wall. This base model describes the time evolution of the…
The pressure dependence of the bulk modulus of glassy polystyrene (PS) was measured in the relatively high-pressure regime, up to 6 GPa, at ambient temperature. For the measurements, PS microbeads were immersed in a pressure medium…
Controlling bacterial surface adhesion and subsequent biofilm formation in fluid systems is crucial for the safety and efficacy of medical and industrial processes. Here, we theoretically examine the transport of bacteria close to surfaces,…
We have investigated the effects of permeable walls, modeled by linear acoustic impedance with zero reactance, on compressible channel flow via linear stability analysis (LSA). Base flow profiles are taken from impermeable isothermal-wall…
Electroosmotic pumping through uncharged hydrogels can be achieved by embedding the polymer network with charged colloidal inclusions. Matos and co-workers (2006) recently used the concept to enhance the diffusion-limited flux of uncharged…
In this work a continuum model for high frequency poroelastic longitudinal waves in hydrogels is presented. A viscoelastic force describing the interaction between the polymer network and the bounded water present in such materials is…
Complex fluids such as emulsions, colloidal gels, polymer or surfactant solutions are all characterized by the existence of a "microstructure" which may couple to an external flow on timescales that are easily probed in experiments. Such a…
Inexpensive, portable lab-on-a-chip devices would revolutionize fields like environmental monitoring and global health, but current microfluidic chips are tethered to extensive off-chip hardware. Insects, however, are self-contained and…
Many familiar events feature a distinctive sound: paper crumpling or tearing, squeaking doors, drumming rain or boiling water. Such characteristic sounds actually carry a profusion of informations about the fleeting physical processes at…