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Within developing embryos, tissues flow and reorganize dramatically on timescales as short as minutes. This includes epithelial tissues, which often narrow and elongate in convergent extension movements due to anisotropies in external…

Tissues and Organs · Quantitative Biology 2020-06-24 Xun Wang , Matthias Merkel , Leo B. Sutter , Gonca Erdemci-Tandogan , M. Lisa Manning , Karen E. Kasza

An example of capillary phenomena commonly seen and often studied is a droplet of water hanging in air from a horizontal surface. A thin capillary surface interface between the liquid and gas develops tangential surface tension, which…

Fluid Dynamics · Physics 2019-04-09 Dale G. Karr

The displacement of a fluid by another less viscous one in a quasi-two dimensional geometry typically leads to complex fingering patterns. In an isotropic system, dense-branching growth arises, which is characterized by repeated…

Fluid Dynamics · Physics 2021-01-19 Qing Zhang , Amin Amooie , Martin Z. Bazant , Irmgard Bischofberger

Connecting cell behavior to tissue shape and mechanics is a key challenge in the physics of morphogenesis. Cytoskeletal turnover precludes a fixed reference state, and tensions are actively generated independently of strain; so conventional…

Soft Condensed Matter · Physics 2026-05-28 Nikolas H. Claussen , Fridtjof Brauns , Boris I. Shraiman

Surface growth is a crucial component of many natural and artificial processes from cell proliferation to additive manufacturing. In elastic systems surface growth is usually accompanied by the development of geometrical incompatibility…

Soft Condensed Matter · Physics 2019-05-08 Lev Truskinovsky , Giuseppe Zurlo

We investigate the impact of an anisotropic surface tension on the late-stage dilute phase separation dynamics, revisiting the seminal Lifshitz-Slyozov (LS) theory, which traditionally relies on the assumption of isotropic surface tension.…

Statistical Mechanics · Physics 2025-12-02 Arjun R. Anand , Melinda M. Andrews , Benjamin P. Vollmayr-Lee

The hydrodynamic theory of active nematics has been often used to describe the spatio-temporal dynamics of cell flows and motile topological defects within soft confluent tissues. Those theories, however, often rely on the assumption that…

Soft Condensed Matter · Physics 2023-08-15 Ioannis Hadjifrangiskou , Liam J. Ruske , Julia M. Yeomans

Young's law fails on soft solid and liquid substrates where there are substantial deformations near the contact line. On liquid substrates, this is captured by Neumann's classic analysis, which provides a geometrical construction for…

Soft Condensed Matter · Physics 2015-03-13 Robert W. Style , Eric R. Dufresne

The Young-Laplace's equation is established based on liquid membrane without shearing resistance. It is not valid for solid. By taking into account the in-plane shearing and transverse shearing within the surface layer, we reconstruct the…

Materials Science · Physics 2018-11-30 Zaixing Huang

We study a shape evolution framework in which the deformation of shapes from time t to t + dt is governed by a regularized anisotropic elasticity model. More precisely, we assume that at each time shapes are infinitesimally deformed from a…

Optimization and Control · Mathematics 2019-01-01 Dai-Ni Hsieh , Sylvain Arguillère , Nicolas Charon , Michael I. Miller , Laurent Younes

By solving the Young Laplace equation of capillary hydrostatics one can accurately determine equilibrium shapes of droplets on relatively smooth solid surfaces. The solution, however of the Young Laplace equation becomes tricky when a…

Soft Condensed Matter · Physics 2013-06-05 Nikolaos T. Chamakos , Michail E. Kavousanakis , Athanasios G. Papathanasiou

Physical experiments can characterize the elastic response of granular materials in terms of macroscopic state-variables, namely volume (packing) fraction and stress, while the microstructure is not accessible and thus neglected. Here, by…

Soft Condensed Matter · Physics 2015-06-16 Nishant Kumar , Stefan Luding , Vanessa Magnanimo

A new phase field model of microstructural evolution is presented that includes the effects of elastic strain energy. The model's thin interface behavior is investigated by mapping it onto a recent model developed by Echebarria et al (Phys…

Materials Science · Physics 2008-10-29 Michael Greenwood , Jeffrey J. Hoyt , Nikolas Provatas

The notion of tissue surface tension has provided a physical understanding of morphogenetic phenomena such as tissue spreading or cell sorting. The measurement of tissue surface tension so far relied on strong approximations on the…

Biological Physics · Physics 2009-11-13 Cyrille Norotte , Francoise Marga , Adrian Neagu , Ioan Kosztin , Gabor Forgacs

Biological cells can actively tune their intracellular architecture according to their overall shape. Here we explore the rheological implication of such coupling in a minimal model of a dense cellular material where each cell exerts an…

Soft Condensed Matter · Physics 2022-04-13 Shao-Zhen Lin , Matthias Merkel , Jean-François Rupprecht

We investigate the mechanical interplay between the spatial organization of the actin cytoskeleton and the shape of animal cells adhering on micropillar arrays. Using a combination of analytical work, computer simulations and in vitro…

We propose a sharp interface model for simulating solid-state dewetting where the surface energy is (weakly) anisotropic. The morphology evolution of thin films is governed by surface diffusion and contact line migration. The mathematical…

Materials Science · Physics 2015-06-22 Yan Wang , Wei Jiang , Weizhu Bao , Dave J. Srolovitz

The simulation of growth processes within soft biological tissues is of utmost importance for many applications in the medical sector. Within this contribution we propose a new macroscopic approach fro modelling stress-driven volumetric…

Computational Engineering, Finance, and Science · Computer Science 2022-01-21 L. Lamm , H. Holthusen , T. Brepols , S. Jockenhövel , S. Reese

A living cell actively generates traction forces on its environment with its actin cytoskeleton. These forces deform the cell elastic substrate which, in turn, affects the traction forces exerted by the cell and can consequently modify the…

Biological Physics · Physics 2022-02-03 H. Chelly , A. Jahangiri , M. Mireux , J. Étienne , D. K. Dysthe , C. Verdier , P. Recho

The Young-Dupr\'e equation is a cornerstone of the equilibrium theory of capillary and wetting phenomena. In the biological world, interfacial phenomena are ubiquitous, from the spreading of bacterial colonies to tissue growth and flocking…

Soft Condensed Matter · Physics 2026-04-16 Yongfeng Zhao , Ruben Zakine , Adrian Daerr , Yariv Kafri , Julien Tailleur , Frédéric van Wijland
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