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With the increasing demand for personalized health monitoring, wearable sensors have gained attention in medical diagnostics and physiological tracking. Hydrogels, known for their mechanical properties and similarity to biological tissues,…

Thiol-ene photo-click hydrogels were prepared via step-growth polymerisation using thiol-functionalised type-I collagen and 8-arm poly(ethylene glycol) norbornene terminated (PEG-NB), as a potential injectable regenerative device. Type-I…

Chemical Physics · Physics 2017-06-12 Roisin Holmes , Xuebin B Yang , Aishling Dunne , Larisa Florea , David Wood , Giuseppe Tronci

In this work, we review previously developed coarse-grained (CG) particle models for biological membrane and red blood cells (RBCs) and discuss the advantages of the CG particle method over the continuum and atomic simulations on modeling…

Soft Condensed Matter · Physics 2017-07-18 He Li , Hung-yu Chang , Jun Yang , Lu Lu , George Lykotrafitis

The creation of hyaluronic acid (HA)-based materials as biomineralisation scaffolds for cost-effective hard tissue regenerative therapies remains a key biomedical challenge. A non-toxic and simple acellular method to generate specific…

Biological Physics · Physics 2021-01-08 Ziyu Gao , Layla Hassouneh , Xuebin Yang , Juan Pang , Paul D. Thornton , Giuseppe Tronci

One of the limitations of electrospun collagen as bone-like fibrous structure is the potential collagen triple helix denaturation in the fibre state and the corresponding inadequate wet stability even after crosslinking. Here, we have…

Biological Physics · Physics 2015-09-21 M. Tarik Arafat , Giuseppe Tronci , Jie Yin , David J. Wood , Stephen J. Russell

Optically accessible, scalable planar nanofluidic channels are attractive for studying transport and localization under confinement. Two dimensional (2D) materials provide large area, atomically flat interfaces for generating such…

Osseointegration is crucial to the success of biomedical implants. Additive manufacturing of implants offers a high degree of design freedom, enabling precise control over implant geometry and material composition. Bioactive glass (BG) can…

Organic solar cells (OSCs) containing an active layer consisting of a nanostructured blend of a conjugated polymer like poly(3-hexylthiophene) (P3HT) and an electron acceptor molecule have the potential of competing against silicon-based…

Materials Science · Physics 2020-09-25 Li Quan , Dongrun Ju , Stephanie Lee , Dilhan M. Kalyon

The design and optimization of photobioreactors (PBR) can benefit from the development of robust and yet quantitatively accurate computational models, that incorporate the complex interplay of fundamental phenomena. At a minimum, the…

Physicochemically informed biological sequence generation has the potential to accelerate computer-aided cellular therapy, yet current models fail to \emph{jointly} ensure novelty, diversity, and biophysical plausibility when designing…

Computational Engineering, Finance, and Science · Computer Science 2025-10-08 Jiahao Ma , Hongzong Li , Ye-Fan Hu , Jian-Dong Huang

This paper proposes an innovative solution to the growing issue of greenhouse gas emissions: a closed photobioreactor (PBR) facade system to mitigate greenhouse gas (GHG) concentrations. With digital fabrication technology, this study…

Computational Engineering, Finance, and Science · Computer Science 2026-04-30 Xiujin Liu

Understanding the semiconductor-electrolyte interface in photoelectrochemical (PEC) systems is crucial for optimizing stability and reactivity. Despite the challenges in establishing reliable surface structure models during PEC cycles, this…

Materials Science · Physics 2024-12-12 Yonghyuk Lee , Taehun Lee

The tissue source of type I collagen is critical to ensure scalability and regulation-friendly clinical translation of new medical device prototypes. However, the selection of a commercial source of collagen that fulfils both aforementioned…

Tissues and Organs · Quantitative Biology 2022-01-28 Charles Brooker , Giuseppe Tronci

Polymer gels with photo-responsive cross-links enable tunable mechanics and surface morphologies, making them promising for adaptive materials. While prior work on coumarin cross-linked gels has focused on photo-mediated events in dilute…

Reactive, semi-permeable interfaces play important roles in key biological processes such as targeted drug delivery, lipid metabolism, and signal transduction. These systems involve coupled surface reactions, transmembrane transport, and…

Numerical Analysis · Mathematics 2025-07-22 Weidong Shi , Shixin Xu , Zhen Zhang , Quan Zhao

Hydrogen is considered a promising environmentally friendly energy carrier for replacing traditional fossil fuels. In this context, photoelectrochemical (PEC) cells effectively convert solar energy directly to H2 fuel by water…

Applied Physics · Physics 2019-03-22 Sebastiano Bellani , Maria Rosa Antognazza , Francesco Bonaccorso

We report measurements of the frequency-dependent shear moduli of aging colloidal systems that evolve from a purely low-viscosity liquid to a predominantly elastic glass or gel. Using microrheology, we measure the local complex shear…

Soft Condensed Matter · Physics 2009-11-13 S. Jabbari-Farouji , M. Atakhorram , D. Mizuno , E. Eiser , G. H. Wegdam , F. C. MacKintosh , Daniel Bonn , C. F. Schmidt

Clinical trials previously demonstrated the notable capacity to elicit visual percepts in blind patients affected with retinal diseases by electrically stimulating the remaining neurons on the retina. However, these implants restored very…

Bone structure is generally hierarchically organized into organic (collagen, proteins,...), inorganic (hydroxyapatite (HAP)) components. However, many fundamental mechanisms of the biomineralization processes such as HAP formation, the…

Collagen micro fibrils bio mimetically intercalate graphitic structures in aqueous media to form graphene nano platelets collagen complex (G Cl). Synthesized G Cl based stable, aqueous bio nanocolloids exhibit anomalously augmented charge…

Biological Physics · Physics 2015-12-01 Purbarun Dhar , Soumya Bhattacharya , Suprabha Nayar , Sarit K. Das