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Large language models (LLMs) have shown promise in medical domains, but their ability to handle specialized neurological reasoning requires systematic evaluation. We developed a comprehensive benchmark using 305 questions from Israeli Board…

Information Retrieval · Computer Science 2025-08-21 Moran Sorka , Alon Gorenshtein , Dvir Aran , Shahar Shelly

During the first step of practical reasoning, i.e. deliberation or goals selection, an intelligent agent generates a set of pursuable goals and then selects which of them he commits to achieve. Explainable Artificial Intelligence (XAI)…

Artificial Intelligence · Computer Science 2020-09-15 Mariela Morveli-Espinoza , Cesar Augusto Tacla , Henrique Jasinski

The delivery of appropriate targeted therapies to cancer patients requires the complete analysis of the molecular profiling of tumors and the patient's clinical characteristics in the context of existing knowledge and recent findings…

Computation and Language · Computer Science 2024-12-13 Ting He , Kory Kreimeyer , Mimi Najjar , Jonathan Spiker , Maria Fatteh , Valsamo Anagnostou , Taxiarchis Botsis

Rare diseases affect over 300 million individuals worldwide, yet timely and accurate diagnosis remains an urgent challenge. Patients often endure a prolonged diagnostic odyssey exceeding five years, marked by repeated referrals,…

Computation and Language · Computer Science 2026-02-17 Weike Zhao , Chaoyi Wu , Yanjie Fan , Xiaoman Zhang , Pengcheng Qiu , Yuze Sun , Xiao Zhou , Yanfeng Wang , Xin Sun , Ya Zhang , Yongguo Yu , Kun Sun , Weidi Xie

The human-centric explainable artificial intelligence (HCXAI) community has raised the need for framing the explanation process as a conversation between human and machine. In this position paper, we establish desiderata for Mediators,…

Computation and Language · Computer Science 2022-06-14 Nils Feldhus , Ajay Madhavan Ravichandran , Sebastian Möller

Research in cognitive psychology has established that whether people prefer simpler explanations to complex ones is context dependent, but the question of `simple vs. complex' becomes critical when an artificial agent seeks to explain its…

Human-Computer Interaction · Computer Science 2024-03-20 Michelle Blom , Ronal Singh , Tim Miller , Liz Sonenberg , Kerry Trentelman , Adam Saulwick

Motivation: Many high-performance DTA models have been proposed, but they are mostly black-box and thus lack human interpretability. Explainable AI (XAI) can make DTA models more trustworthy, and can also enable scientists to distill…

Artificial Intelligence · Computer Science 2021-06-03 Tri Minh Nguyen , Thomas P Quinn , Thin Nguyen , Truyen Tran

There is a need for socially assistive robots (SARs) to provide transparency in their behavior by explaining their reasoning. Additionally, the reasoning and explanation should represent the user's preferences and goals. To work towards…

Robotics · Computer Science 2020-12-08 Jason R. Wilson , Leilani Gilpin , Irina Rabkina

Autonomous multi-agent systems (MAS) are useful for automating complex tasks but raise trust concerns due to risks such as miscoordination or goal misalignment. Explainability is vital for users' trust calibration, but explainable MAS face…

Artificial Intelligence · Computer Science 2025-10-30 Bálint Gyevnár , Christopher G. Lucas , Stefano V. Albrecht , Shay B. Cohen

We grapple with the question: How, for whom and why should explainable artificial intelligence (XAI) aim to support the user goal of agency? In particular, we analyze the relationship between agency and explanations through a user-centric…

Human-Computer Interaction · Computer Science 2023-12-07 Iyadunni Adenuga , Jonathan Dodge

Answering complex medical questions requires not only domain expertise and patient-specific information, but also structured and multi-perspective reasoning. Existing multi-agent approaches often rely on fixed roles or shallow interaction…

Artificial Intelligence · Computer Science 2026-03-04 Siqi Ma , Jiajie Huang , Fan Zhang , Yue Shen , Jinlin Wu , Guohui Fan , Zhu Zhang , Zelin Zang

Understandable and persuasive recommendations support the electricity consumers' behavioral change to tackle the energy efficiency problem. Generating load shifting recommendations for household appliances as explainable increases the…

Multiagent Systems · Computer Science 2023-01-05 Alona Zharova , Annika Boer , Julia Knoblauch , Kai Ingo Schewina , Jana Vihs

Inferring the abstract relational and causal structure of the world is a major challenge for reinforcement-learning (RL) agents. For humans, language--particularly in the form of explanations--plays a considerable role in overcoming this…

Table Question Answering (TableQA) enables natural language interaction with structured tabular data. However, existing large language model (LLM) approaches face critical limitations: context length constraints that restrict data handling…

Artificial Intelligence · Computer Science 2026-03-11 Tong Wang , Chi Jin , Yongkang Chen , Huan Deng , Xiaohui Kuang , Gang Zhao

Precision therapeutics require multimodal adaptive models that generate personalized treatment recommendations. We introduce TxAgent, an AI agent that leverages multi-step reasoning and real-time biomedical knowledge retrieval across a…

Artificial Intelligence · Computer Science 2025-03-17 Shanghua Gao , Richard Zhu , Zhenglun Kong , Ayush Noori , Xiaorui Su , Curtis Ginder , Theodoros Tsiligkaridis , Marinka Zitnik

Algorithmic solutions have significant potential to improve decision-making across various domains, from healthcare to e-commerce. However, the widespread adoption of these solutions is hindered by a critical challenge: the lack of…

Machine Learning · Computer Science 2025-03-11 Zuzanna Bączek , Michał Bizoń , Aneta Pawelec , Piotr Sankowski

We motivate and introduce CHARD: Clinical Health-Aware Reasoning across Dimensions, to investigate the capability of text generation models to act as implicit clinical knowledge bases and generate free-flow textual explanations about…

Computation and Language · Computer Science 2023-02-14 Steven Y. Feng , Vivek Khetan , Bogdan Sacaleanu , Anatole Gershman , Eduard Hovy

As the field of explainable AI (XAI) is maturing, calls for interactive explanations for (the outputs of) AI models are growing, but the state-of-the-art predominantly focuses on static explanations. In this paper, we focus instead on…

Artificial Intelligence · Computer Science 2023-06-12 Antonio Rago , Hengzhi Li , Francesca Toni

In the context of explainable artificial intelligence (XAI), limited research has identified role-specific explanation needs. This study investigates the explanation needs of data scientists, who are responsible for training, testing,…

Human-Computer Interaction · Computer Science 2025-02-25 Helmut Degen , Ziran Min , Parinitha Nagaraja

Extracting implicit knowledge and logical reasoning abilities from large language models (LLMs) has consistently been a significant challenge. The advancement of multi-agent systems has further en-hanced the capabilities of LLMs. Inspired…

Artificial Intelligence · Computer Science 2025-09-23 Hailong Yang , Mingxian Gu , Renhuo Zhao , Fuping Hu , Zhaohong Deng , Yitang Chen