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Radiotherapy (RT) is a key component in the treatment of various cancers, including Acute Lymphocytic Leukemia (ALL) and Acute Myelogenous Leukemia (AML). Precise delineation of organs at risk (OARs) and target areas is essential for…

Computer Vision and Pattern Recognition · Computer Science 2023-11-14 Ricardo Coimbra Brioso , Damiano Dei , Ciro Franzese , Nicola Lambri , Daniele Loiacono , Pietro Mancosu , Marta Scorsetti

Personalized ultra-fractionated stereotactic adaptive radiotherapy (PULSAR) is a novel treatment that delivers radiation in pulses of protracted intervals. Accurate prediction of gross tumor volume (GTV) changes through regression models…

Machine Learning · Computer Science 2025-09-18 Yajun Yu , Steve Jiang , Robert Timmerman , Hao Peng

Medical ultrasound (US) imaging is widely used in clinical examinations due to its portability, real-time capability, and radiation-free nature. To address inter- and intra-operator variability, robotic ultrasound systems have gained…

Robotics · Computer Science 2025-07-29 Yifan Zhang , Dianye Huang , Nassir Navab , Zhongliang Jiang

Quantitative ultrasound (QUS) methods provide a promising framework that can non-invasively and inexpensively be used to predict or assess the tumour response to cancer treatment. The first step in using the QUS methods is to select a…

Computer Vision and Pattern Recognition · Computer Science 2016-02-09 Hamid R. Tizhoosh , Mehrdad J. Gangeh , Hadi Tadayyon , Gregory J. Czarnota

Radiation therapy (RT) requires precise dose delivery over multiple fractions, with CT fundamental for treatment planning due to its electron density information. Repeated CT acquisitions impose radiation exposure and logistical burdens,…

The development of algorithms for automation of subtasks during robotic surgery can be accelerated by the availability of realistic simulation environments. In this work, we focus on one aspect of the realism of a surgical simulator, which…

Robotics · Computer Science 2024-06-12 Juan Antonio Barragan , Hisashi Ishida , Adnan Munawar , Peter Kazanzides

Magnetic resonance imaging (MRI) enables 3-D imaging of anatomical structures. However, the acquisition of MR volumes with high spatial resolution leads to long scan times. To this end, we propose volumetric super-resolution forests (VSRF)…

Computer Vision and Pattern Recognition · Computer Science 2018-02-16 Aline Sindel , Katharina Breininger , Johannes Käßer , Andreas Hess , Andreas Maier , Thomas Köhler

Spine injections are commonly performed in several clinical procedures. The localization of the target vertebral level (i.e. the position of a vertebra in a spine) is typically done by back palpation or under X-ray guidance, yielding either…

Image and Video Processing · Electrical Eng. & Systems 2020-02-27 Maria Tirindelli , Maria Victorova , Javier Esteban , Seong Tae Kim , David Navarro-Alarcon , Yong Ping Zheng , Nassir Navab

Thyroid cancer is said to be the second most common type of cancer in female individuals and the third in males by 2030, according to projections. In general, detecting cancer in its early stages improves the chance of survival of the…

Computer Vision and Pattern Recognition · Computer Science 2026-05-29 J. R. González , É. O. Rodrigues , C. P. Damião , C. A. P. Fontes , A. C. Silva , A. C. Paiva , H. Li , C. Du , A. Conci

Volume visualization is a method that displays three-dimensional (3D) data in two-dimensional (2D) space. Using 3D datasets instead of 2D traditional images improves the visualization of anatomical structures, and volume visualization helps…

We describe a visual computing approach to radiation therapy (RT) planning, based on spatial similarity within a patient cohort. In radiotherapy for head and neck cancer treatment, dosage to organs at risk surrounding a tumor is a large…

Medical Physics · Physics 2019-10-14 A. Wentzel , P. Hanula , T. Luciani , B. Elgohari , H. Elhalawani , G. Canahuate , D. Vock , C. D. Fuller , G. E. Marai

Rb-82 is a radioactive isotope widely used for cardiac PET imaging. Despite numerous benefits of 82-Rb, there are several factors that limits its image quality and quantitative accuracy. First, the short half-life of 82-Rb results in noisy…

Telerobotic and Autonomous Robotic Ultrasound Systems (RUS) help alleviate the need for operator-dependability in free-hand ultrasound examinations. However, the state-of-the-art RUSs still rely on a human operator to apply the ultrasound…

Robotics · Computer Science 2024-07-01 Deepak Raina , Ziming Zhao , Richard Voyles , Juan Wachs , Subir K. Saha , S. H. Chandrashekhara

$\textbf{Purpose:}$ To assess the viability of a physics-based, deterministic and adjoint-capable algorithm for performing treatment planning system independent dose calculations and for computing dosimetric differences caused by anatomical…

Medical Physics · Physics 2024-04-02 Tiberiu Burlacu , Danny Lathouwers , Zoltán Perkó

Radiotherapy treatment planning currently requires many trail-and-error iterations between the planner and treatment planning system, as well as between the planner and physician for discussion/consultation. The physician's preferences for…

Medical Physics · Physics 2019-08-01 Dan Nguyen , Azar Sadeghnejad Barkousaraie , Chenyang Shen , Xun Jia , Steve Jiang

Thyroid cancer is the most common endocrine malignancy, and accurately distinguishing between benign and malignant thyroid tumors is crucial for developing effective treatment plans in clinical practice. Pathologically, thyroid tumors pose…

Image and Video Processing · Electrical Eng. & Systems 2024-01-04 Jia Dong , Yao Yao , Yang Dong , Hui Ma

Transrectal biopsies under 2D ultrasound (US) control are the current clinical standard for prostate cancer diagnosis. The isoechogenic nature of prostate carcinoma makes it necessary to sample the gland systematically, resulting in a low…

Computer Vision and Pattern Recognition · Computer Science 2011-07-11 Michael Baumann , Pierre Mozer , Vincent Daanen , Jocelyne Troccaz

The Radiotherapy treatment planning optimization process based on a quasi-Newton algorithm with an object function containing dose-volume constraints is not guaranteed to converge when the dose value in the dose-volume constraint is a…

Classical Analysis and ODEs · Mathematics 2008-12-02 I. Hoveijn

Fusing intra-operative 2D transrectal ultrasound (TRUS) image with pre-operative 3D magnetic resonance (MR) volume to guide prostate biopsy can significantly increase the yield. However, such a multimodal 2D/3D registration problem is a…

Image and Video Processing · Electrical Eng. & Systems 2021-07-15 Hengtao Guo , Xuanang Xu , Sheng Xu , Bradford J. Wood , Pingkun Yan

X-ray computed tomographic infrastructures are medical imaging modalities that rely on the acquisition of rays crossing examined objects while measuring their intensity decrease. Physical measurements are post-processed by mathematical…

Image and Video Processing · Electrical Eng. & Systems 2022-01-25 Attila Juhos