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Segmentation of axon and myelin from microscopy images of the nervous system provides useful quantitative information about the tissue microstructure, such as axon density and myelin thickness. This could be used for instance to document…

Computer Vision and Pattern Recognition · Computer Science 2018-07-12 Aldo Zaimi , Maxime Wabartha , Victor Herman , Pierre-Louis Antonsanti , Christian Samuel Perone , Julien Cohen-Adad

Quantifying axon and myelin properties (e.g., axon diameter, myelin thickness, g-ratio) in histology images can provide useful information about microstructural changes caused by neurodegenerative diseases. Automatic tissue segmentation is…

Image and Video Processing · Electrical Eng. & Systems 2024-09-19 Armand Collin , Arthur Boschet , Mathieu Boudreau , Julien Cohen-Adad

The electron microscope (EM) remains the predominant technique for elucidating intricate details of the animal nervous system at the nanometer scale. However, accurately reconstructing the complex morphology of axons and myelin sheaths…

Image and Video Processing · Electrical Eng. & Systems 2023-07-06 Ao Cheng , Guoqiang Zhao , Lirong Wang , Ruobing Zhang

The ability to predict patient-specific soft tissue deformations is key for computer-integrated surgery systems and the core enabling technology for a new era of personalized medicine. Element-Free Galerkin (EFG) methods are better suited…

Computational Engineering, Finance, and Science · Computer Science 2019-06-14 Grand Joldes , George Bourantas , Benjamin Zwick , Habib Chowdhury , Adam Wittek , Sudip Agrawal , Konstantinos Mountris , Damon Hyde , Simon K. Warfield , Karol Miller

In modern medical diagnostics, magnetic resonance imaging (MRI) is an important technique that provides detailed insights into anatomical structures. In this paper, we present a comprehensive methodology focusing on streamlining the…

Image and Video Processing · Electrical Eng. & Systems 2024-04-25 Siddharth Jha , Zichen Gui , Benjamin Delbos , Richard Moreau , Arnaud Leleve , Irene Cheng

MRI analysis takes central position in brain tumor diagnosis and treatment, thus it's precise evaluation is crucially important. However, it's 3D nature imposes several challenges, so the analysis is often performed on 2D projections that…

Computer Vision and Pattern Recognition · Computer Science 2018-10-10 Dmitry Lachinov , Evgeny Vasiliev , Vadim Turlapov

Computer assisted technologies based on algorithmic software segmentation are an increasing topic of interest in complex surgical cases. However - due to functional instability, time consuming software processes, personnel resources or…

Electron microscopy (EM) enables the reconstruction of neural circuits at the level of individual synapses, which has been transformative for scientific discoveries. However, due to the complex morphology, an accurate reconstruction of…

Modeling the 3D structures of cells and tissues is crucial in biology. Sequential cross-sectional images from electron microscopy provide high-resolution intracellular structure information. The segmentation of complex cell structures…

Quantitative Methods · Quantitative Biology 2025-02-14 Jin Kousaka , Atsuko H. Iwane , Yuichi Togashi

Gray matter (GM) tissue changes have been associated with a wide range of neurological disorders and was also recently found relevant as a biomarker for disability in amyotrophic lateral sclerosis. The ability to automatically segment the…

Computer Vision and Pattern Recognition · Computer Science 2018-06-22 Christian S. Perone , Evan Calabrese , Julien Cohen-Adad

Recent studies suggest a potential link between the physical structure of mitochondria and neurodegenerative diseases. With advances in Electron Microscopy techniques, it has become possible to visualize the boundary and internal membrane…

Computer Vision and Pattern Recognition · Computer Science 2025-02-11 Faris Serdar Taşel , Efe Çiftci

The glioblastoma multiforme is the most common malignant primary brain tumor and is one of the highest malignant human neoplasms. During the course of disease, the evaluation of tumor volume is an essential part of the clinical follow-up.…

Computer Vision and Pattern Recognition · Computer Science 2011-03-10 Jan Egger , Miriam H. A. Bauer , Daniela Kuhnt , Barbara Carl , Christoph Kappus , Bernd Freisleben , Christopher Nimsky

Advances in image registration and machine learning have recently enabled volumetric analysis of postmortem brain tissue from conventional photographs of coronal slabs, which are routinely collected in brain banks and neuropathology…

The task of automatically segmenting 3-D surfaces representing boundaries of objects is important for quantitative analysis of volumetric images, and plays a vital role in biomedical image analysis. Recently, graph-based methods with a…

Computer Vision and Pattern Recognition · Computer Science 2018-01-10 Abhay Shah , Michael Abramoff , Xiaodong Wu

The skeleton of a digital image is a compact representation of its topology, geometry, and scale. It has utility in many computer vision applications, such as image description, segmentation, and registration. However, skeletonization has…

Computer Vision and Pattern Recognition · Computer Science 2023-09-07 Martin J. Menten , Johannes C. Paetzold , Veronika A. Zimmer , Suprosanna Shit , Ivan Ezhov , Robbie Holland , Monika Probst , Julia A. Schnabel , Daniel Rueckert

Automated sample preparation and electron microscopy enables acquisition of very large image data sets. These technical advances are of special importance to the field of neuroanatomy, as 3D reconstructions of neuronal processes at the nm…

Automated brain tissue segmentation into white matter (WM), gray matter (GM), and cerebro-spinal fluid (CSF) from magnetic resonance images (MRI) is helpful in the diagnosis of neuro-disorders such as epilepsy, Alzheimer's, multiple…

Computer Vision and Pattern Recognition · Computer Science 2018-06-13 Pulkit Kumar , Pravin Nagar , Chetan Arora , Anubha Gupta

Analyzing CT scans, MRIs and X-rays is pivotal in diagnosing and treating diseases. However, detecting and identifying abnormalities from such medical images is a time-intensive process that requires expert analysis and is prone to…

Image and Video Processing · Electrical Eng. & Systems 2025-03-14 Daniel Syomichev , Padmini Gopinath , Guang-Lin Wei , Eric Chang , Ian Gordon , Amanuel Seifu , Rahul Pemmaraju , Neehar Peri , James Purtilo

Accurate 3D brain MRI subtype classification benefits from both localized anatomical cues and long-range contextual reasoning. We present AGA3DNet, a report-grounded framework that incorporates brief anatomical phrases extracted from…

Computer Vision and Pattern Recognition · Computer Science 2026-05-11 Peiyu Duan , Xueqi Guo , Sepehr Farhand , Mehmet Berk Sahin , Xinyuan Zheng , James S. Duncan , Gerardo Hermosillo Valadez , Yoshihisa Shinagawa
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