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Drug repurposing is more relevant than ever due to drug development's rising costs and the need to respond to emerging diseases quickly. Knowledge graph embedding enables drug repurposing using heterogeneous data sources combined with…

Semantic concepts and relations encoded in domain-specific ontologies and other medical semantic resources play a crucial role in deciphering terms in medical queries and documents. The exploitation of these resources for tackling the…

Information Retrieval · Computer Science 2020-05-19 Mohammed Maree , Israa Noor , Khaled Rabayah , Mohammed Belkhatir , Saadat M. Alhashmi

Enriching existing medical terminology knowledge bases (KBs) is an important and never-ending work for clinical research because new terminology alias may be continually added and standard terminologies may be newly renamed. In this paper,…

Computation and Language · Computer Science 2019-09-04 Jiaying Zhang , Zhixing Zhang , Huanhuan Zhang , Zhiyuan Ma , Yangming Zhou , Ping He

This work presents a Biomedical Literature Question Answering (Q&A) system based on a Retrieval-Augmented Generation (RAG) architecture, designed to improve access to accurate, evidence-based medical information. Addressing the shortcomings…

Computation and Language · Computer Science 2025-09-09 Mansi Garg , Lee-Chi Wang , Bhavesh Ghanchi , Sanjana Dumpala , Shreyash Kakde , Yen Chih Chen

Digital libraries in the scientific domain provide users access to a wide range of information to satisfy their diverse information needs. Here, ranking results play a crucial role in users' satisfaction. Exploiting bibliometric metadata,…

Digital Libraries · Computer Science 2024-10-10 Timo Breuer , Christin Katharina Kreutz , Philipp Schaer , Dirk Tunger

In this contribution, we deal with seed-based information retrieval in networks of research publications. Using systematic reviews as a baseline, and publication data from the NIH Open Citation Collection, we compare the performance of the…

Information Retrieval · Computer Science 2024-06-14 Peter Sjögårde , Per Ahlgren

Knowledge graph is a popular format for representing knowledge, with many applications to semantic search engines, question-answering systems, and recommender systems. Real-world knowledge graphs are usually incomplete, so knowledge graph…

Machine Learning · Computer Science 2023-04-26 Hung Nghiep Tran , Atsuhiro Takasu

This paper presents the Entity-Duet Neural Ranking Model (EDRM), which introduces knowledge graphs to neural search systems. EDRM represents queries and documents by their words and entity annotations. The semantics from knowledge graphs…

Information Retrieval · Computer Science 2018-06-05 Zhenghao Liu , Chenyan Xiong , Maosong Sun , Zhiyuan Liu

Question answering is a natural language understanding task that involves reasoning over both explicit context, and unstated relevant domain knowledge. Despite the high cost of training, large language models (LLMs) -- the backbone of most…

Computation and Language · Computer Science 2025-04-24 Laura Cabello , Carmen Martin-Turrero , Uchenna Akujuobi , Anders Søgaard , Carlos Bobed

We introduced a methodology to efficiently exploit natural-language expressed biomedical knowledge for repurposing existing drugs towards diseases for which they were not initially intended. Leveraging on developments in Computational…

Quantitative Methods · Quantitative Biology 2014-06-17 Ruggero Gramatica , T. Di Matteo , Stefano Giorgetti , Massimo Barbiani , Dorian Bevec , Tomaso Aste

Efficiently finding doctors and locations is an important search problem for patients in the healthcare domain, for which traditional information retrieval methods tend not to work optimally. In the last ten years, knowledge graphs (KGs)…

Artificial Intelligence · Computer Science 2023-10-10 Mayank Kejriwal , Hamid Haidarian , Min-Hsueh Chiu , Andy Xiang , Deep Shrestha , Faizan Javed

Objective: Applying large language models (LLMs) to the clinical domain is challenging due to the context-heavy nature of processing medical records. Retrieval-augmented generation (RAG) offers a solution by facilitating reasoning over…

Computation and Language · Computer Science 2025-08-21 Skatje Myers , Timothy A. Miller , Yanjun Gao , Matthew M. Churpek , Anoop Mayampurath , Dmitriy Dligach , Majid Afshar

Evaluating semantic relatedness of Web resources is still an open challenge. This paper focuses on knowledge-based methods, which represent an alternative to corpus-based approaches, and rely in general on the availability of knowledge…

Artificial Intelligence · Computer Science 2023-08-21 Anna Formica , Francesco Taglino

Electronic Medical Records (EMRs), while integral to modern healthcare, present challenges for clinical reasoning and diagnosis due to their complexity and information redundancy. To address this, we proposed medIKAL (Integrating Knowledge…

Computation and Language · Computer Science 2025-02-18 Mingyi Jia , Junwen Duan , Yan Song , Jianxin Wang

Coreference resolution across multiple documents poses a significant challenge in natural language processing, particularly within the domain of knowledge graphs. This study introduces an innovative method aimed at identifying and resolving…

Computation and Language · Computer Science 2025-04-09 Zhang Dong , Mingbang Wang , Songhang deng , Le Dai , Jiyuan Li , Xingzu Liu , Ruilin Nong

A key component of deep learning (DL) for natural language processing (NLP) is word embeddings. Word embeddings that effectively capture the meaning and context of the word that they represent can significantly improve the performance of…

Knowledge Graph embedding provides a versatile technique for representing knowledge. These techniques can be used in a variety of applications such as completion of knowledge graph to predict missing information, recommender systems,…

Information Retrieval · Computer Science 2021-07-19 Shivani Choudhary , Tarun Luthra , Ashima Mittal , Rajat Singh

We introduce a novel graph-based Retrieval-Augmented Generation (RAG) framework specifically designed for the medical domain, called \textbf{MedGraphRAG}, aimed at enhancing Large Language Model (LLM) capabilities for generating…

Computer Vision and Pattern Recognition · Computer Science 2024-10-17 Junde Wu , Jiayuan Zhu , Yunli Qi , Jingkun Chen , Min Xu , Filippo Menolascina , Vicente Grau

Artificial intelligence (AI) is reshaping modern healthcare by advancing disease diagnosis, treatment decision-making, and biomedical research. Among AI technologies, large language models (LLMs) have become especially impactful, enabling…

Artificial Intelligence · Computer Science 2025-11-18 Zhengda Wang , Daqian Shi , Jingyi Zhao , Xiaolei Diao , Xiongfeng Tang , Yanguo Qin

Existing medical RAG systems mainly leverage knowledge from medical knowledge bases, neglecting the crucial role of experiential knowledge derived from similar patient cases -- a key component of human clinical reasoning. To bridge this…

Computation and Language · Computer Science 2025-05-27 Yuxing Lu , Gecheng Fu , Wei Wu , Xukai Zhao , Sin Yee Goi , Jinzhuo Wang