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Linear compartmental models are a widely used tool for analyzing systems arising in biology, medicine, and more. In such settings, it is essential to know whether model parameters can be recovered from experimental data. This is the…

Combinatorics · Mathematics 2025-11-18 Katherine Clemens , Jonathan Martinez , Anne Shiu , Michaela Thompson , Benjamin Warren

Some of the most important compartmental systems, such as irreversible catenary, mamillary and circular systems are symbolically simplified by the method of exact linear lumping. A few symbolically unmanageable systems are numerically…

Classical Analysis and ODEs · Mathematics 2008-02-21 E. Egri , J. Tóth , C. Brochot , F. Y. Bois

A parameter of a mathematical model is structurally identifiable if it can be determined from noiseless experimental data. Here, we examine the identifiability properties of two important classes of linear compartmental models:…

This paper addresses the problem of recovering tracer kinetic parameters from multi-region measurement data in quantitative PET imaging using the reversible two tissue compartment model. Its main result is an extension of our previous work…

Optimization and Control · Mathematics 2025-04-15 Martin Holler , Erion Morina , Georg Schramm

In this work, we consider error detection via simulation for reversible circuit architectures. We rigorously prove that reversibility augments the performance of this simple error detection protocol to a considerable degree. A single…

Hardware Architecture · Computer Science 2023-01-11 Lukas Burgholzer , Robert Wille , Richard Kueng

Important properties of a quantum system are not directly measurable, but they can be disclosed by how fast the system changes under controlled perturbations. In particular, asymmetry and entanglement can be verified by reconstructing the…

The parameters of a linear compartment model are usually estimated from experimental input-output data. A problem arises when infinitely many parameter values can yield the same result; such a model is called unidentifiable. In this case,…

Combinatorics · Mathematics 2016-03-08 Jasmijn A. Baaijens , Jan Draisma

Compartmental models based on tracer mass balance are extensively used in clinical and pre-clinical nuclear medicine in order to obtain quantitative information on tracer metabolism in the biological tissue. This paper is the first of a…

Quantitative Methods · Quantitative Biology 2018-08-21 Fabrice Delbary , Sara Garbarino , Valentina Vivaldi

We propose simple schemes that can perfectly identify projective measurement apparatus secretly chosen from a finite set. Entanglements are used in these schemes both to make possible the perfect identification and to improve the efficiency…

Quantum Physics · Physics 2007-05-23 Zhengfeng Ji , Yuan Feng , Runyao Duan , Mingsheng Ying

Careful analysis of cluster separability opens a way to a completely new understanding of preparation and registration procedures for microsystems: they are changes of separation status. An important observation is that quantum mechanics…

Quantum Physics · Physics 2010-03-23 Petr Hajicek

Detecting entanglement in many-body quantum systems is crucial but challenging, typically requiring multiple measurements. Here, we establish the class of states where measuring connected correlations in just $\textit{one}$ basis is…

Quantum Physics · Physics 2024-04-05 Roopayan Ghosh , Sougato Bose

Identifiability concerns finding which unknown parameters of a model can be estimated from given input-output data. If some subset of the parameters of a model cannot be determined given input-output data, then we say the model is…

Algebraic Geometry · Mathematics 2014-11-03 Nicolette Meshkat , Seth Sullivant , Marisa Eisenberg

A general and computable criterion for k-(in)separability in continuous multipartite quantum systems is presented. The criterion can be experimentally implemented with a finite and comparatively low number of local observables. We discuss…

Quantum Physics · Physics 2012-02-07 Andreas Gabriel , Marcus Huber , Sasa Radic , Beatrix C. Hiesmayr

We propose a classification of measurement apparatuses based on their reliability and accessibility. Our notion of reliability parameterises the possibility of getting unexpected wrong results when using the apparatus in a given time…

Quantum Physics · Physics 2024-07-26 Nicola Pranzini , Paola Verrucchi

Any observable with finite eigenvalue spectrum can be measured using a multiport apparatus realizing an appropriate unitary transformation and an array of detector instruments, where each detector operates as an indicator of one possible…

General Physics · Physics 2022-05-06 Michael Zirpel

A combinatorial characterization of measurable filters on a countable set is found. We apply it to the problem of measurability of the intersection of nonmeasurable filters.

Logic · Mathematics 2007-05-23 Tomek Bartoszynski

The concept of measurement in classical scattering is interpreted as an overlap of a particle packet with some area in phase space that describes the detector. Considering that usually we record the passage of particles at some point in…

Classical Physics · Physics 2010-04-27 C Jung , T H Seligman , J M Torres

In this article, we revisit the century-old question of the minimal set of observables needed to identify a quantum state: here, we replace the natural coincidences in their spectra by effective ones, induced by an imperfect measurement. We…

Quantum Physics · Physics 2016-07-04 Mark Olchanyi , Eugene Moskovets

We show that any unitary transformation performed on the quantum state of a closed quantum system, describes an inner, reversible, generalized quantum measurement. We also show that under some specific conditions it is possible to perform a…

Quantum Physics · Physics 2009-11-11 Paola Zizzi

Identifiability concerns finding which unknown parameters of a model can be quantified from given input-output data. Many linear ODE models, used in systems biology and pharmacokinetics, are unidentifiable, which means that parameters can…

Algebraic Geometry · Mathematics 2013-12-12 Nicolette Meshkat , Seth Sullivant
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