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An efficient monotone data augmentation (MDA) algorithm is proposed for missing data imputation for incomplete multivariate nonnormal data that may contain variables of different types, and are modeled by a sequence of regression models…

Methodology · Statistics 2018-11-21 Yongqiang Tang

Clinical prediction models must be developed using sufficiently large datasets to minimise overfitting and ensure robust predictive performance. Existing sample size calculations assume complete predictor data for all included participants,…

Envelope method was recently proposed as a method to reduce the dimension of responses in multivariate regressions. However, when there exists missing data, the envelope method using the complete case observations may lead to biased and…

Methodology · Statistics 2021-03-25 Linquan Ma , Lan Liu , Wei Yang

Missingness is a common occurrence in educational assessment and psychological measurement. It could not be casually ignored as it may threaten the validity of the test if not handled properly. Considering the difference between omitted and…

Methodology · Statistics 2019-04-09 Jinxin Guo

High throughput metabolomics data are fraught with both non-ignorable missing observations and unobserved factors that influence a metabolite's measured concentration, and it is well known that ignoring either of these complications can…

Methodology · Statistics 2019-09-09 Chris McKennan , Carole Ober , Dan Nicolae

While machine learning (ML) methods have received a lot of attention in recent years, these methods are primarily for prediction. Empirical researchers conducting policy evaluations are, on the other hand, pre-occupied with causal problems,…

Machine Learning · Statistics 2019-03-04 Noemi Kreif , Karla DiazOrdaz

Missing data is a widespread problem in many domains, creating challenges in data analysis and decision making. Traditional techniques for dealing with missing data, such as excluding incomplete records or imputing simple estimates (e.g.,…

Databases · Computer Science 2024-01-09 Massimo Perini , Milos Nikolic

Missing data is an important problem in machine learning practice. Starting from the premise that imputation methods should preserve the causal structure of the data, we develop a regularization scheme that encourages any baseline…

Machine Learning · Computer Science 2021-11-08 Trent Kyono , Yao Zhang , Alexis Bellot , Mihaela van der Schaar

Background: Multiple imputation is often used to reduce bias and gain efficiency when there is missing data. The most appropriate imputation method depends on the model the analyst is interested in fitting. Several imputation approaches…

Methodology · Statistics 2022-11-29 Matthew J. Smith , Matteo Quartagno , Edmund Njeru Njagi

Nonignorable missing data, where the probability of missingness depends on unobserved values, presents a significant challenge in statistical analysis. Traditional methods often rely on strong parametric assumptions that are difficult to…

Methodology · Statistics 2025-09-19 Yujie Zhao

Advances in artificial intelligence (AI) and deep learning have led to neural networks being used to generate lightning-speed answers to complex science questions, paintings in the style of Monet, or stories like those of Twain. Leveraging…

Methodology · Statistics 2026-02-25 Matthew Sainsbury-Dale , Andrew Zammit-Mangion , Noel Cressie , Raphaël Huser

Missing data is a common problem in medical research, and is commonly addressed using multiple imputation. Although traditional imputation methods allow for valid statistical inference when data are missing at random (MAR), their…

Mobile technology (e.g., mobile phones and wearable devices) provides scalable methods for collecting physiological and behavioral biomarkers in patients' naturalistic settings, as well as opportunities for therapeutic advancements and…

In the age of digital healthcare, passively collected physical activity profiles from wearable sensors are a preeminent tool for evaluating health outcomes. In order to fully leverage the vast amounts of data collected through wearable…

Due to the cost or interference of measurement, we need to control measurement system. Assuming that each variable can be measured sequentially, there exists optimal policy choosing next measurement for the former observations. Though…

Machine Learning · Computer Science 2022-04-11 Seongwook Yoon , Jaehyun Kim , Heejeong Lim , Sanghoon Sull

Routinely collected data from electronic health records (EHR) provide opportunities to study effects of longitudinal treatment strategies in real-world clinical settings. A challenge presented by EHR data is that frequency of covariate…

Applications · Statistics 2026-04-14 Leah Pirondini , Karla Diaz-Ordaz , Edward Palmer , Ruth H. Keogh

Missing data is a common problem which has consistently plagued statisticians and applied analytical researchers. While replacement methods like mean-based or hot deck imputation have been well researched, emerging imputation techniques…

Methodology · Statistics 2022-12-27 Seema Sangari , Herman E. Ray

We provide guidance on multiple imputation of missing at random treatments in observational studies. Specifically, analysts should account for both covariates and outcomes, i.e., not just use propensity scores, when imputing the missing…

Methodology · Statistics 2025-01-23 Joseph Feldman , Jerome P. Reiter

We propose a novel approach to leveraging pre-trained language models (LMs) for early forecasting of academic trajectories in STEM students using high-dimensional longitudinal experiential data. This data, which captures students'…

Machine Learning · Computer Science 2025-03-31 Ahatsham Hayat , Bilal Khan , Mohammad Rashedul Hasan

In certain privacy-sensitive scenarios within fields such as clinical trial simulations, federated learning, and distributed learning, researchers often face the challenge of estimating correlations between variables without access to…

Methodology · Statistics 2025-08-05 Longwen Shang , Min Tsao , Xuekui Zhang