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Large Language Model (LLM) inference is hard. The autoregressive Decode phase of the underlying Transformer model makes LLM inference fundamentally different from training. Exacerbated by recent AI trends, the primary challenges are memory…

Hardware Architecture · Computer Science 2026-02-10 Xiaoyu Ma , David Patterson

Machine learning (ML) has emerged into formidable force for identifying hidden but pertinent patterns within a given data set with the objective of subsequent generation of automated predictive behavior. In the recent years, it is safe to…

High-throughput approximations of quantum mechanics calculations and combinatorial experiments have been traditionally used to reduce the search space of possible molecules, drugs and materials. However, the interplay of structural and…

Quantum Physics · Physics 2019-10-29 Alain Tchagang , Julio Valdés

Deep learning is currently being hyped as an almost magical tool for solving all kinds of difficult problems that computers have not been able to solve in the past. Particularly in the fields of computer vision and natural language…

Computational Physics · Physics 2024-05-01 Peter R. Wiecha

Atomic-scale modeling has advanced rapidly through integration of machine learning, yet a key bottleneck remains. Even with an accurate potential energy surface and a clear target material, we still lack a practical atomistic dynamics…

Materials Science · Physics 2026-05-18 Wonseok Jeong , Francesca Tavazza , Brian DeCost

Many important physical processes have dynamics that are too complex to completely model analytically. Optimisation of such processes often relies on intuition, trial-and-error, or the construction of empirical models. Machine learning…

The rapid advancement of artificial intelligence (AI) has brought significant challenges to the education and workforce skills required to take advantage of AI for human-AI collaboration in the workplace. As AI continues to reshape…

Artificial Intelligence · Computer Science 2024-05-31 Margarida Romero

In the last few years, quantum computing and machine learning fostered rapid developments in their respective areas of application, introducing new perspectives on how information processing systems can be realized and programmed. The…

This is an opinion paper about the strengths and weaknesses of Deep Nets for vision. They are at the heart of the enormous recent progress in artificial intelligence and are of growing importance in cognitive science and neuroscience. They…

Computer Vision and Pattern Recognition · Computer Science 2020-11-26 Alan L. Yuille , Chenxi Liu

We are investigating cognitive issues in learning quantum mechanics in order to develop effective teaching and learning tools. The analysis of cognitive issues is particularly important for bridging the gap between the quantitative and…

Physics Education · Physics 2016-02-19 Chandralekha Singh , Guangtian Zhu

Algorithms have been fundamental to recent global technological advances and, in particular, they have been the cornerstone of technical advances in one field rapidly being applied to another. We argue that algorithms possess fundamentally…

Machine Learning · Computer Science 2021-08-09 Petar Veličković , Charles Blundell

Recent research in artificial intelligence and machine learning has largely emphasized general-purpose learning and ever-larger training sets and more and more compute. In contrast, I propose a hybrid, knowledge-driven, reasoning-based…

Artificial Intelligence · Computer Science 2020-02-20 Gary Marcus

Self-supervised learning has recently gained growing interest in molecular modeling for scientific tasks such as AI-assisted drug discovery. Current studies consider leveraging both 2D and 3D molecular structures for representation…

Machine Learning · Computer Science 2023-10-10 Qiying Yu , Yudi Zhang , Yuyan Ni , Shikun Feng , Yanyan Lan , Hao Zhou , Jingjing Liu

Deep learning is catalyzing a scientific revolution fueled by big data, accessible toolkits, and powerful computational resources, impacting many fields including protein structural modeling. Protein structural modeling, such as predicting…

Biomolecules · Quantitative Biology 2020-07-17 Wenhao Gao , Sai Pooja Mahajan , Jeremias Sulam , Jeffrey J. Gray

Machine learning (ML) is a subfield of artificial intelligence. The term applies broadly to a collection of computational algorithms and techniques that train systems from raw data rather than a priori models. ML techniques are now…

The integration of artificial intelligence (AI) into science education is transforming the design and function of learning materials, offering new affordances for personalization, authenticity, and accessibility. This chapter examines how…

Computers and Society · Computer Science 2026-02-25 Xiaoming Zhai , Kent Crippen

Machine learning is poised as a very powerful tool that can drastically improve our ability to carry out scientific research. However, many issues need to be addressed before this becomes a reality. This article focuses on one particular…

Computational Physics · Physics 2020-06-05 Weinan E , Jiequn Han , Linfeng Zhang

Although learning in high dimensions is commonly believed to suffer from the curse of dimensionality, modern machine learning methods often exhibit an astonishing power to tackle a wide range of challenging real-world learning problems…

Machine Learning · Computer Science 2022-07-12 Lechao Xiao , Jeffrey Pennington

The introduction of generative artificial intelligence applications to the public has led to heated discussions about its potential impacts and risks for K-12 education. One particular challenge has been to decide what students should learn…

Computers and Society · Computer Science 2026-02-20 Yasmin Kafai , Shuchi Grover

Machine learning has become a premier tool in physics and other fields of science. It has been shown that the quantum mechanical scattering problem can not only be solved with such techniques, but it was argued that the underlying neural…

Computational Physics · Physics 2021-02-08 Bastian Kaspschak , Ulf-G. Meißner