English
Related papers

Related papers: Ambiguous Dynamic Treatment Regimes: A Reinforceme…

200 papers

The data drawn from biological, economic, and social systems are often confounded due to the presence of unmeasured variables. Prior work in causal discovery has focused on discrete search procedures for selecting acyclic directed mixed…

Machine Learning · Computer Science 2021-02-26 Rohit Bhattacharya , Tushar Nagarajan , Daniel Malinsky , Ilya Shpitser

This paper studies the cumulative causal effects of sequential treatments in the presence of unmeasured confounders. It is a critical issue in sequential decision-making scenarios where treatment decisions and outcomes dynamically evolve…

Machine Learning · Computer Science 2025-05-15 Yingrong Wang , Anpeng Wu , Baohong Li , Ziyang Xiao , Ruoxuan Xiong , Qing Han , Kun Kuang

Sequential multiple assignment randomized trials (SMARTs) are used to construct data-driven optimal intervention strategies for subjects based on their intervention and covariate histories in different branches of health and behavioral…

Methodology · Statistics 2022-04-28 Palash Ghosh , Xiaoxi Yan , Bibhas Chakraborty

Modern medical research demands specialized causal inference methods evaluating complex continuous-time dynamic treatment regimens using observational data. For instance, obtaining the causal effects of intravenous administration, a…

Methodology · Statistics 2026-04-02 Haiyan Zhu , Yingchun Zhou

In clinical practice, physicians make a series of treatment decisions over the course of a patient's disease based on his/her baseline and evolving characteristics. A dynamic treatment regime is a set of sequential decision rules that…

Methodology · Statistics 2015-02-04 Phillip J. Schulte , Anastasios A. Tsiatis , Eric B. Laber , Marie Davidian

One of the main goals of sequential, multiple assignment, randomized trials (SMART) is to find the most efficacious design embedded dynamic treatment regimes. The analysis method known as multiple comparisons with the best (MCB) allows…

Methodology · Statistics 2020-08-07 William J. Artman , Ashkan Ertefaie , Kevin G. Lynch , James R. McKay

Estimating causal treatment effects in observational settings is frequently compromised by selection bias arising from unobserved confounders. While traditional econometric methods struggle when these confounders are orthogonal to…

Artificial Intelligence · Computer Science 2026-01-06 Ahmed Dawoud , Osama El-Shamy

Retrieval-augmented generation (RAG) enhances large language models (LLMs) by incorporating external knowledge, but existing approaches indiscriminately trigger retrieval and rely on single-path evidence construction, often introducing…

Computation and Language · Computer Science 2026-01-08 Wang Chen , Guanqiang Qi , Weikang Li , Yang Li , Deguo Xia , Jizhou Huang

Clinical machine learning applications are often plagued with confounders that are clinically irrelevant, but can still artificially boost the predictive performance of the algorithms. Confounding is especially problematic in mobile health…

Applications · Statistics 2018-11-29 Elias Chaibub Neto

We propose and analyze a continuous-time robust reinforcement learning framework for optimal stopping under ambiguity. In this framework, an agent chooses a robust exploratory stopping time motivated by two objectives: robust…

Optimization and Control · Mathematics 2026-04-17 Junyan Ye , Hoi Ying Wong , Kyunghyun Park

Convenient access to observational data enables us to learn causal effects without randomized experiments. This research direction draws increasing attention in research areas such as economics, healthcare, and education. For example, we…

Social and Information Networks · Computer Science 2019-12-03 Ruocheng Guo , Jundong Li , Huan Liu

Underactuated systems like sea vessels have degrees of motion that are insufficiently matched by a set of independent actuation forces. In addition, the underlying trajectory-tracking control problems grow in complexity in order to decide…

Systems and Control · Electrical Eng. & Systems 2021-04-02 Mohammed Abouheaf , Wail Gueaieb , Md. Suruz Miah , Davide Spinello

Transfer reinforcement learning aims to improve the sample efficiency of solving unseen new tasks by leveraging experiences obtained from previous tasks. We consider the setting where all tasks (MDPs) share the same environment dynamic…

Machine Learning · Computer Science 2021-01-08 Kaige Yang

Data-driven methods for personalizing treatment assignment have garnered much attention from clinicians and researchers. Dynamic treatment regimes formalize this through a sequence of decision rules that map individual patient…

Methodology · Statistics 2022-02-22 Eric J. Rose , Erica E. M. Moodie , Susan Shortreed

A dynamic treatment regime effectively incorporates both accrued information and long-term effects of treatment from specially designed clinical trials. As these become more and more popular in conjunction with longitudinal data from…

Methodology · Statistics 2011-08-29 Rui Song , Weiwei Wang , Donglin Zeng , Michael R. Kosorok

We study the identification and estimation of long-term treatment effects when both experimental and observational data are available. Since the long-term outcome is observed only after a long delay, it is not measured in the experimental…

Methodology · Statistics 2024-09-04 Guido Imbens , Nathan Kallus , Xiaojie Mao , Yuhao Wang

Decision Transformers (DT) play a crucial role in modern reinforcement learning, leveraging offline datasets to achieve impressive results across various domains. However, DT requires high-quality, comprehensive data to perform optimally.…

Artificial Intelligence · Computer Science 2025-05-15 Minh Hoang Nguyen , Linh Le Pham Van , Thommen George Karimpanal , Sunil Gupta , Hung Le

Dynamic real-time optimization (DRTO) is a challenging task due to the fact that optimal operating conditions must be computed in real time. The main bottleneck in the industrial application of DRTO is the presence of uncertainty. Many…

This research addresses the challenge of conducting interpretable causal inference between a binary treatment and its resulting outcome when not all confounders are known. Confounders are factors that have an influence on both the treatment…

Machine Learning · Computer Science 2023-10-24 Sohaib Kiani , Jared Barton , Jon Sushinsky , Lynda Heimbach , Bo Luo

Delayed Markov decision processes (DMDPs) fulfill the Markov property by augmenting the state space of agents with a finite time window of recently committed actions. In reliance on these state augmentations, delay-resolved reinforcement…

Robotics · Computer Science 2025-11-17 Mohammadhossein Malmir , Josip Josifovski , Noah Klarmann , Alois Knoll