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The high-content image-based assay is commonly leveraged for identifying the phenotypic impact of genetic perturbations in biology field. However, a persistent issue remains unsolved during experiments: the interferential technical noise…
The dispute of how the human brain represents conceptual knowledge has been argued in many scientific fields. Brain imaging studies have shown that the spatial patterns of neural activation in the brain are correlated with thinking about…
Neuroimaging studies, such as the Human Connectome Project (HCP), often collect multi-faceted and multi-block data to study the complex human brain. However, these data are often analyzed in a pairwise fashion, which can hinder our…
Complex functional brain network analyses have exploded over the last eight years, gaining traction due to their profound clinical implications. The application of network science (an interdisciplinary offshoot of graph theory) has…
Recent advances in neuroimaging have deepened our understanding of the brain's complex functional and structural organization. Among these, functional Magnetic Resonance Imaging (fMRI) - particularly resting-state fMRI (rs-fMRI) - has…
Neurofibromatosis type 1 (NF1) is an autosomal dominant tumor predisposition syndrome that involves the central and peripheral nervous systems. Accurate detection and segmentation of neurofibromas are essential for assessing tumor burden…
In the current paper, we introduce a parametric data-driven model for functional near-infrared spectroscopy that decomposes a signal into a series of independent, rescaled, time-shifted, hemodynamic basis functions. Each decomposed waveform…
Accurate diagnosis of psychiatric disorders plays a critical role in improving the quality of life for patients and potentially supports the development of new treatments. Many studies have been conducted on machine learning techniques that…
Deep neural networks (DNNs) have achieved exceptional performances in many tasks, particularly, in supervised classification tasks. However, achievements with supervised classification tasks are based on large datasets with well-separated…
Cognition in midlife is an important predictor of age-related mental decline and statistical models that predict cognitive performance can be useful for predicting decline. However, existing models struggle to capture complex relationships…
Large health surveys increasingly collect high-dimensional functional data from wearable devices, and function on scalar regression (FoSR) is often used to quantify the relationship between these functional outcomes and scalar covariates…
Functional connectivity (FC) refers to the investigation of interactions between brain regions to understand integration of neural activity in several regions. FC is often estimated using functional magnetic resonance images (fMRI). There…
In this paper, we provide a comprehensive analysis of periocular-based sex-prediction (commonly referred to as gender classification) using state-of-the-art machine learning techniques. In order to reflect a more challenging scenario where…
Academic achievement is a critical measure of intellectual ability, prompting extensive research into cognitive tasks as potential predictors. Neuroimaging technologies, such as functional near-infrared spectroscopy (fNIRS), offer insights…
We propose a new approach, called as functional deep neural network (FDNN), for classifying multi-dimensional functional data. Specifically, a deep neural network is trained based on the principle components of the training data which shall…
Graph neural networks have emerged as a promising approach for the analysis of non-Euclidean data such as meshes. In medical imaging, mesh-like data plays an important role for modelling anatomical structures, and shape classification can…
Functional magnetic resonance imaging (fMRI) has become one of the most common imaging modalities for brain function analysis. Recently, graph neural networks (GNN) have been adopted for fMRI analysis with superior performance.…
This study investigated age-related changes in functional connectivity using resting-state fMRI and explored the efficacy of traditional deep learning for classifying brain developmental stages (BDS). Functional connectivity was assessed…
Human brains exhibit highly organized multiscale neurophysiological dynamics. Understanding those dynamic changes and the neuronal networks involved is critical for understanding how the brain functions in health and disease. Functional…
Functional subnetwork extraction is commonly used to explore the brain's modular structure. However, reliable subnetwork extraction from functional magnetic resonance imaging (fMRI) data remains challenging due to the pronounced noise in…