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This paper explores the significant impact of AI-based medical devices, including wearables, telemedicine, large language models, and digital twins, on clinical decision support systems. It emphasizes the importance of producing outcomes…

Artificial Intelligence · Computer Science 2024-04-11 Elham Nasarian , Roohallah Alizadehsani , U. Rajendra Acharya , Kwok-Leung Tsui

This paper evaluates the user interface of an in vitro fertility (IVF) outcome prediction tool, focussing on its understandability for patients or potential patients. We analyse four years of anonymous patient feedback, followed by a user…

Human-Computer Interaction · Computer Science 2025-06-24 Adarsa Sivaprasad , Ehud Reiter , David McLernon , Nava Tintarev , Siladitya Bhattacharya , Nir Oren

Interpretability is essential for machine learning algorithms in high-stakes application fields such as medical image analysis. However, high-performing black-box neural networks do not provide explanations for their predictions, which can…

Computer Vision and Pattern Recognition · Computer Science 2023-08-09 Susu Sun , Stefano Woerner , Andreas Maier , Lisa M. Koch , Christian F. Baumgartner

Recommender systems are indispensable for helping users navigate the immense item catalogs of modern online platforms. Recently, generative recommendation has emerged as a promising paradigm, unifying the conventional retrieve-and-rank…

Information Retrieval · Computer Science 2025-09-12 Dengzhao Fang , Jingtong Gao , Chengcheng Zhu , Yu Li , Xiangyu Zhao , Yi Chang

The close coupling of artificial intelligence (AI) and electroencephalography (EEG) has substantially advanced human-computer interaction (HCI) technologies in the AI era. Different from traditional EEG systems, the interpretability and…

Signal Processing · Electrical Eng. & Systems 2025-08-19 Xinliang Zhou , Chenyu Liu , Jinan Zhou , Zhongruo Wang , Liming Zhai , Ziyu Jia , Cuntai Guan , Yang Liu

The misuse of generative AI in online disinformation campaigns highlights the urgent need for transparent and explainable detection systems. In this work, we investigate how detectors for AI-generated images can be more effective in…

Computer Vision and Pattern Recognition · Computer Science 2026-05-08 Silvia Poletti , Justin Ilyes , Marcel Hasenbalg , David Fischinger , Martin Boyer

It has been observed that deep neural networks (DNNs) often use both genuine as well as spurious features. In this work, we propose "Amending Inherent Interpretability via Self-Supervised Masking" (AIM), a simple yet interestingly effective…

Computer Vision and Pattern Recognition · Computer Science 2025-08-18 Eyad Alshami , Shashank Agnihotri , Bernt Schiele , Margret Keuper

Transformers have had a significant impact on natural language processing and have recently demonstrated their potential in computer vision. They have shown promising results over convolution neural networks in fundamental computer vision…

Computer Vision and Pattern Recognition · Computer Science 2023-11-14 Rojina Kashefi , Leili Barekatain , Mohammad Sabokrou , Fatemeh Aghaeipoor

Interpretability methods for image classification assess model trustworthiness by attempting to expose whether the model is systematically biased or attending to the same cues as a human would. Saliency methods for feature attribution…

Machine Learning · Statistics 2021-04-08 Jacob Pfau , Albert T. Young , Jerome Wei , Maria L. Wei , Michael J. Keiser

Uncertainty is a fundamental challenge in medical practice, but current medical AI systems fail to explicitly quantify or communicate uncertainty in a way that aligns with clinical reasoning. Existing XAI works focus on interpreting model…

Artificial Intelligence · Computer Science 2025-09-24 Xiuyi Fan

For automatic human figure drawing (HFD) assessment tasks, such as diagnosing autism spectrum disorder (ASD) using HFD images, the clarity and explainability of a model decision are crucial. Existing pixel-level attribution-based…

Computer Vision and Pattern Recognition · Computer Science 2024-10-07 Jongseo Lee , Geo Ahn , Seong Tae Kim , Jinwoo Choi

Despite AI's superhuman performance in a variety of domains, humans are often unwilling to adopt AI systems. The lack of interpretability inherent in many modern AI techniques is believed to be hurting their adoption, as users may not trust…

Artificial Intelligence · Computer Science 2021-11-17 Daehwan Ahn , Abdullah Almaatouq , Monisha Gulabani , Kartik Hosanagar

Automated decision-making systems are becoming increasingly ubiquitous, which creates an immediate need for their interpretability and explainability. However, it remains unclear whether users know what insights an explanation offers and,…

Human-Computer Interaction · Computer Science 2024-09-27 Yueqing Xuan , Edward Small , Kacper Sokol , Danula Hettiachchi , Mark Sanderson

Data visualizations are powerful tools for communicating patterns in quantitative data. Yet understanding any data visualization is no small feat -- succeeding requires jointly making sense of visual, numerical, and linguistic inputs…

Human-Computer Interaction · Computer Science 2025-05-26 Arnav Verma , Kushin Mukherjee , Christopher Potts , Elisa Kreiss , Judith E. Fan

The interpretation of implicit meanings is an integral aspect of human communication. However, this framework may not transfer to interactions with Large Language Models (LLMs). To investigate this, we introduce the task of Implicit…

Computation and Language · Computer Science 2026-04-21 Antonio De Santis , Tommaso Bonetti , Andrea Tocchetti , Marco Brambilla

Diffusion large language models generate text through multi-step denoising, where hallucination signals may emerge throughout the trajectory rather than only in the final output. Existing detectors mainly rely on output uncertainty or…

Computation and Language · Computer Science 2026-05-18 Guoshenghui Zhao , Tan Yu , Weijie Zhao

Deep learning-based AI models have been extensively applied in genomics, achieving remarkable success across diverse applications. As these models gain prominence, there exists an urgent need for interpretability methods to establish…

Genomics · Quantitative Biology 2025-05-16 Chenyu Wang , Chaoying Zuo , Zihan Su , Yuhang Xing , Lu Li , Maojun Wang , Zeyu Zhang

We introduce Discovering Conceptual Network Explanations (DCNE), a new approach for generating human-comprehensible visual explanations to enhance the interpretability of deep neural image classifiers. Our method automatically finds visual…

Computer Vision and Pattern Recognition · Computer Science 2024-07-09 Neehar Kondapaneni , Markus Marks , Oisin Mac Aodha , Pietro Perona

A variety of methods exist to explain image classification models. However, whether they provide any benefit to users over simply comparing various inputs and the model's respective predictions remains unclear. We conducted a user study…

Machine Learning · Computer Science 2022-04-26 Leon Sixt , Martin Schuessler , Oana-Iuliana Popescu , Philipp Weiß , Tim Landgraf

This paper argues that interpretability research in Artificial Intelligence (AI) is fundamentally ill-posed as existing definitions of interpretability fail to describe how interpretability can be formally tested or designed for. We posit…

Artificial Intelligence · Computer Science 2026-01-30 Pietro Barbiero , Mateo Espinosa Zarlenga , Francesco Giannini , Alberto Termine , Filippo Bonchi , Mateja Jamnik , Giuseppe Marra