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The dynamic instability of the living systems and the "superposition" of different forms of randomness are viewed as a component of the contingently increasing organization of life along evolution. We briefly survey how classical and…

Other Quantitative Biology · Quantitative Biology 2011-04-07 Marcello Buiatti , Giuseppe Longo

A celebrated and controversial hypothesis conjectures that some biological systems --parts, aspects, or groups of them-- may extract important functional benefits from operating at the edge of instability, halfway between order and…

Statistical Mechanics · Physics 2018-08-01 Miguel A. Munoz

Collective cell migration plays an essential role in various biological processes, such as development or cancer proliferation. While cell-cell interactions are clearly key determinants of collective cell migration -- in addition to…

Collective cell migration plays a central role in tissue development, morphogenesis, wound repair and cancer progression. With the growing realization that physical forces mediate cell motility in development and physiology, a key…

Biological Physics · Physics 2018-12-07 Shiladitya Banerjee , M. Cristina Marchetti

Understanding the emergence and evolution of multicellularity and cellular differentiation is a core problem in biology. We develop a quantitative model that shows that a multicellular form emerges from genetically identical unicellular…

Populations and Evolution · Quantitative Biology 2017-02-07 Iaroslav Ispolatov , Martin Ackermann , Michael Doebeli

Through extensive studies of dynamical system modeling cellular growth and reproduction, we find evidence that complexity arises in multicellular organisms naturally through evolution. Without any elaborate control mechanism, these systems…

Adaptation and Self-Organizing Systems · Physics 2009-10-31 Chikara Furusawa , Kunihiko Kaneko

Jamming transition is traditionally regarded as a geometric transition governed by static contact networks. Recently, dynamic phase transitions of athermal particles under periodic shearing provide a new lens on this problem, leading to a…

Statistical Mechanics · Physics 2026-04-24 He-Da Wang , Bo Wang , Qun-Li Lei , Yu-Qiang Ma

Community assembly is studied using individual-based multispecies models. The models have stochastic population dynamics with mutation, migration, and extinction of species. Mutants appear as a result of mutation of the resident species,…

Populations and Evolution · Quantitative Biology 2010-05-18 Yohsuke Murase , Takashi Shimada , Nobuyasu Ito , Per Arne Rikvold

Many of the biological phenomena involve collective dynamics driven by self-propelled motion and nonequilibrium force (i.e., activity) that result in features unexpected from equilibrium physics. On the other hand, biological experiments…

Soft Condensed Matter · Physics 2020-09-08 Lisa Yamauchi , Tomoya Hayata , Masahito Uwamichi , Tomoki Ozawa , Kyogo Kawaguchi

Background: Recent models of genome-proteome evolution have shown that some of the key traits displayed by the global structure of cellular networks might be a natural result of a duplication-diversification (DD) process. One of the…

Genomics · Quantitative Biology 2007-05-23 Ricard V. Sole , Pau Fernandez

Locomotion is essential for living cells. It enables bacteria and algae to explore space for food, cancer to spread, and immune system to fight infections. Motile cells display trajectories of intriguing complexity, from regular (e.g.…

Soft Condensed Matter · Physics 2021-12-28 C. Misbah , M. S. Rizvi , W. F. Hu , T. S. Lin , S. Rafai , A. Farutin

Cell invasion and spatial pattern formation are two distinct manifestations of cellular self-organisation in development, regeneration, and disease. Here, we develop and analyse a unified theoretical framework that links these two seemingly…

Tissues and Organs · Quantitative Biology 2026-04-30 Carles Falcó , Samuel W. S. Johnson , Mohit P. Dalwadi , Philip K. Maini

We investigate the evolution of a single qubit subject to a continuous unitary dynamics and an additional interrupting influence which occurs periodically. One may imagine a dynamically evolving closed quantum system which becomes open at…

Quantum Physics · Physics 2009-11-07 Juergen Audretsch , Lajos Diosi , Thomas Konrad

Cell movement has essential functions in development, immunity and cancer. Various cell migration patterns have been reported and a general rule has recently emerged, the so-called UCSP (Universal Coupling between cell Speed and cell…

Analysis of PDEs · Mathematics 2019-12-17 Christèle Etchegaray , Nicolas Meunier , Raphael Voituriez

In complex systems, the interplay between nonlinear and stochastic dynamics, e.g., J. Monod's necessity and chance, gives rise to an evolutionary process in Darwinian sense, in terms of discrete jumps among attractors, with punctuated…

Adaptation and Self-Organizing Systems · Physics 2013-03-18 Hong Qian

Metabolism displays striking and robust regularities in the forms of modularity and hierarchy, whose composition may be compactly described. This renders metabolic architecture comprehensible as a system, and suggests the order in which…

Molecular Networks · Quantitative Biology 2015-06-05 Rogier Braakman , Eric Smith

A single mechanism, endemic to the standard model of physics, is proposed to explain wavefunction collapse, classical motion, dissipation, equilibration, and the transition from pure quantum mechanics through open system decoherence to the…

General Physics · Physics 2024-09-23 J. H. Brownell

Dense suspensions of swimming bacteria are known to exhibit collective behaviour arising from the interplay of steric and hydrodynamic interactions. Unconfined suspensions exhibit transient, recurring vortices and jets, whereas those…

Biological Physics · Physics 2016-07-04 Hugo Wioland , Enkeleida Lushi , Raymond E. Goldstein

The emergence of collective motion, also known as flocking or swarming, in groups of moving individuals who orient themselves using only information from their neighbors is a very general phenomenon that is manifested at multiple spatial…

Statistical Mechanics · Physics 2016-04-26 David A. Quint , Ajay Gopinathan

In vivo and in vitro systems of cells and extra-cellular matrix (ECM) systems are well known to form ordered patterns of orientationally aligned fibers. Here, we interpret them as active analogs of the (disordered) isotropic to the…

Soft Condensed Matter · Physics 2025-04-11 Haiqian Yang , Ming Guo , L. Mahadevan
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