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The rapid expansion of publicly-available medical data presents a challenge for clinicians and researchers alike, increasing the gap between the volume of scientific literature and its applications. The steady growth of studies and findings…

Artificial Intelligence · Computer Science 2025-08-06 Taine J. Elliott , Stephen P. Levitt , Ken Nixon , Martin Bekker

Knowledge bases often consist of facts which are harvested from a variety of sources, many of which are noisy and some of which conflict, resulting in a level of uncertainty for each triple. Knowledge bases are also often incomplete,…

Artificial Intelligence · Computer Science 2021-04-13 Xuelu Chen , Michael Boratko , Muhao Chen , Shib Sankar Dasgupta , Xiang Lorraine Li , Andrew McCallum

Uncertainty estimation has been widely studied in medical image segmentation as a tool to provide reliability, particularly in deep learning approaches. However, previous methods generally lack effective supervision in uncertainty…

Computer Vision and Pattern Recognition · Computer Science 2025-10-15 Yuzhu Li , An Sui , Fuping Wu , Xiahai Zhuang

Various strategies for active learning have been proposed in the machine learning literature. In uncertainty sampling, which is among the most popular approaches, the active learner sequentially queries the label of those instances for…

Machine Learning · Computer Science 2019-09-04 Vu-Linh Nguyen , Sébastien Destercke , Eyke Hüllermeier

Large language models (LLMs) often generate fluent but factually incorrect outputs, known as hallucinations, which undermine their reliability in real-world applications. While uncertainty estimation has emerged as a promising strategy for…

Machine Learning · Computer Science 2025-05-13 Pei-Fu Guo , Yun-Da Tsai , Shou-De Lin

Probabilistic knowledge graph embeddings represent entities as distributions, using learned variances to quantify epistemic uncertainty. We identify a fundamental limitation: these variances are relation-agnostic, meaning an entity receives…

Machine Learning · Computer Science 2026-01-05 Chorok Lee

Scientific information expresses human understanding of nature. This knowledge is largely disseminated in different forms of text, including scientific papers, news articles, and discourse among people on social media. While important for…

Computation and Language · Computer Science 2025-07-01 Dustin Wright

The tension between qualitative theorizing and quantitative methods is pervasive in the social sciences, and poses a constant challenge to empirical research. But in science studies as an interdisciplinary specialty, there are additional…

Digital Libraries · Computer Science 2015-05-25 Loet Leydesdorff

We address the problem of uncertainty quantification and propose measures of total, aleatoric, and epistemic uncertainty based on a known decomposition of (strictly) proper scoring rules, a specific type of loss function, into a divergence…

Machine Learning · Computer Science 2025-05-29 Paul Hofman , Yusuf Sale , Eyke Hüllermeier

This study investigates uncertainty quantification in large language models (LLMs) for medical applications, emphasizing both technical innovations and philosophical implications. As LLMs become integral to clinical decision-making,…

Artificial Intelligence · Computer Science 2025-04-08 Zahra Atf , Seyed Amir Ahmad Safavi-Naini , Peter R. Lewis , Aref Mahjoubfar , Nariman Naderi , Thomas R. Savage , Ali Soroush

When using scientific literature to model scholarly discourse, a research specialty can be operationalized as an evolving set of related documents. Each publication can be expected to contribute to the further development of the specialty…

Digital Libraries · Computer Science 2009-11-24 Diana Lucio-Arias , Loet Leydesdorff

A new combinatorial-probabilistic diagnostic entropy has been introduced. It describes the pair-wise sum of probabilities of system conditions that have to be distinguished during the diagnosing process. The proposed measure describes the…

Information Theory · Computer Science 2009-09-29 Henryk Borowczyk

Large Language Models (LLMs) are increasingly used in clinical settings, where sensitivity to linguistic uncertainty can influence diagnostic interpretation and decision-making. Yet little is known about where such epistemic cues are…

Computation and Language · Computer Science 2025-12-01 Srivarshinee Sridhar , Raghav Kaushik Ravi , Kripabandhu Ghosh

In research policy, effective measures that lead to improvements in the generation of knowledge must be based on reliable methods of research assessment, but for many countries and institutions this is not the case. Publication and citation…

Digital Libraries · Computer Science 2018-07-20 Alonso Rodriguez-Navarro , Ricardo Brito

We present a novel approach to uncertainty quantification in classification tasks based on label-wise decomposition of uncertainty measures. This label-wise perspective allows uncertainty to be quantified at the individual class level,…

Machine Learning · Computer Science 2024-06-05 Yusuf Sale , Paul Hofman , Timo Löhr , Lisa Wimmer , Thomas Nagler , Eyke Hüllermeier

Accurate healthcare prediction is essential for improving patient outcomes. Existing work primarily leverages advanced frameworks like attention or graph networks to capture the intricate collaborative (CO) signals in electronic health…

Machine Learning · Computer Science 2025-04-02 Chuang Zhao , Hui Tang , Jiheng Zhang , Xiaomeng Li

Healthcare foundation models have largely followed paradigms from natural language processing and computer vision, emphasizing large scale pretraining and deterministic representations over heterogeneous clinical data. However, clinical…

Machine Learning · Computer Science 2026-04-07 Qian Zhou , Yuanyun Zhang , Shi Li

Decomposing predictive uncertainty into epistemic (model ignorance) and aleatoric (data ambiguity) components is central to reliable decision making, yet most methods estimate both from the same predictive distribution. Recent empirical and…

Machine Learning · Computer Science 2026-02-13 Tanmoy Mukherjee , Marius Kloft , Pierre Marquis , Zied Bouraoui

We develop a novel application of hybrid information divergences to analyze uncertainty in steady-state subsurface flow problems. These hybrid information divergences are non-intrusive, goal-oriented uncertainty quantification tools that…

Probability · Mathematics 2019-07-05 Eric Joseph Hall , Markos A. Katsoulakis

A biosignal is a signal that can be continuously measured from human bodies, such as respiratory sounds, heart activity (ECG), brain waves (EEG), etc, based on which, machine learning models have been developed with very promising…

Machine Learning · Computer Science 2022-01-26 Tong Xia , Jing Han , Cecilia Mascolo