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Cancer diseases constitute one of the most significant societal challenges. In this paper, we introduce a novel histopathological dataset for prostate cancer detection. The proposed dataset, consisting of over 2.6 million tissue patches…

Data cleaning consumes about 80% of the time spent on data analysis for clinical research projects. This is a much bigger problem in the era of big data and machine learning in the field of medicine where large volumes of data are being…

Medical Physics · Physics 2018-01-03 Timothy Rozario , Troy Long , Mingli Chen , Weiguo Lu , Steve Jiang

Background: Deep learning (DL)-based organ segmentation is increasingly used in radiotherapy, yet voxel-wise DL uncertainty maps are rarely presented to clinicians. Purpose: This study assessed how DL-generated uncertainty maps impact…

In cancer therapeutics, protein-metal binding mechanisms critically govern the pharmacokinetics and targeting efficacy of drugs, thereby fundamentally shaping the rational design of anticancer metallodrugs. While conventional laboratory…

Radiological imaging of prostate is becoming more popular among researchers and clinicians in searching for diseases, primarily cancer. Scans might be acquired at different times, with patient movement between scans, or with different…

Computer Vision and Pattern Recognition · Computer Science 2013-11-05 Xin Zhao , Arie Kaufman

The PI-CAI (Prostate Imaging: Cancer AI) challenge led to expert-level diagnostic algorithms for clinically significant prostate cancer detection. The algorithms receive biparametric MRI scans as input, which consist of T2-weighted and…

Image and Video Processing · Electrical Eng. & Systems 2024-07-01 Alessa Hering , Sarah de Boer , Anindo Saha , Jasper J. Twilt , Mattias P. Heinrich , Derya Yakar , Maarten de Rooij , Henkjan Huisman , Joeran S. Bosma

Prostate cancer is the second-most frequently diagnosed cancer and the sixth leading cause of cancer death in males worldwide. The main problem that specialists face during the diagnosis of prostate cancer is the localization of Regions of…

Image and Video Processing · Electrical Eng. & Systems 2022-07-21 Pablo Cesar Quihui-Rubio , Gilberto Ochoa-Ruiz , Miguel Gonzalez-Mendoza , Gerardo Rodriguez-Hernandez , Christian Mata

Background: Radiography (X-rays) is the dominant modality in orthopedics, and improving the interpretation of radiographs is clinically relevant. Machine learning (ML) has revolutionized data analysis and has been applied to medicine, with…

Computer Vision and Pattern Recognition · Computer Science 2024-08-27 Jakub Olczak , Max Gordon

In the last years, the weakly supervised paradigm of multiple instance learning (MIL) has become very popular in many different areas. A paradigmatic example is computational pathology, where the lack of patch-level labels for whole-slide…

Computer Vision and Pattern Recognition · Computer Science 2023-10-31 Pablo Morales-Álvarez , Arne Schmidt , José Miguel Hernández-Lobato , Rafael Molina

Analyzing and inspecting bone marrow cell cytomorphology is a critical but highly complex and time-consuming component of hematopathology diagnosis. Recent advancements in artificial intelligence have paved the way for the application of…

Computer Vision and Pattern Recognition · Computer Science 2022-05-23 Shayan Fazeli , Alireza Samiei , Thomas D. Lee , Majid Sarrafzadeh

Most recently, the pathology diagnosis of cancer is shifting to integrating molecular makers with histology features. It is a urgent need for digital pathology methods to effectively integrate molecular markers with histology, which could…

Image and Video Processing · Electrical Eng. & Systems 2023-06-28 Xiaofei Wang , Stephen Price , Chao Li

Prostate cancer is the most diagnosed form of cancer in Canadian men, and is the third leading cause of cancer death. Despite these statistics, prognosis is relatively good with a sufficiently early diagnosis, making fast and reliable…

Computer Vision and Pattern Recognition · Computer Science 2015-10-21 Audrey G. Chung , Mohammad Javad Shafiee , Devinder Kumar , Farzad Khalvati , Masoom A. Haider , Alexander Wong

In preoperative imaging, the demarcation of rectal cancer with magnetic resonance images provides an important basis for cancer staging and treatment planning. Recently, deep learning has greatly improved the state-of-the-art method in…

Computer Vision and Pattern Recognition · Computer Science 2020-01-01 Joohyung Lee , Ji Eun Oh , Min Ju Kim , Bo Yun Hur , Dae Kyung Sohn

Accurate prediction of biochemical recurrence (BCR) after radical prostatectomy is critical for guiding adjuvant treatment and surveillance decisions in prostate cancer. However, existing clinicopathological risk models reduce complex…

This paper proposes an Incremental Learning (IL) approach to enhance the accuracy and efficiency of deep learning models in analyzing T2-weighted (T2w) MRI medical images prostate cancer detection using the PI-CAI dataset. We used multiple…

Computer Vision and Pattern Recognition · Computer Science 2025-04-29 Sara Yavari , Jacob Furst

Melanoma is the deadliest form of skin cancer. Automated skin lesion analysis plays an important role for early detection. Nowadays, the ISIC Archive and the Atlas of Dermoscopy dataset are the most employed skin lesion sources to benchmark…

Computer Vision and Pattern Recognition · Computer Science 2026-04-21 Alceu Bissoto , Michel Fornaciali , Eduardo Valle , Sandra Avila

Accurate segmentation of prostate cancer histopathology images is crucial for diagnosis and treatment planning. This study presents a comparative analysis of three deep learning-based methods, Mamba, SAM, and YOLO, for segmenting prostate…

Computer Vision and Pattern Recognition · Computer Science 2024-10-04 Ali Badiezadeh , Amin Malekmohammadi , Seyed Mostafa Mirhassani , Parisa Gifani , Majid Vafaeezadeh

Recent advances in deep learning algorithms have led to significant benefits for solving many medical image analysis problems. Training deep learning models commonly requires large datasets with expert-labeled annotations. However,…

Computer Vision and Pattern Recognition · Computer Science 2023-09-19 Banafshe Felfeliyan , Abhilash Hareendranathan , Gregor Kuntze , Stephanie Wichuk , Nils D. Forkert , Jacob L. Jaremko , Janet L. Ronsky

AI-assisted nuclei segmentation in histopathological images is a crucial task in the diagnosis and treatment of cancer diseases. It decreases the time required to manually screen microscopic tissue images and can resolve the conflict…

Image and Video Processing · Electrical Eng. & Systems 2023-11-21 Hesham Ali , Idriss Tondji , Mennatullah Siam

Background: Many open-source skin cancer image datasets are the result of clinical trials conducted in countries with lighter skin tones. Due to this tone imbalance, machine learning models derived from these datasets can perform well at…

Image and Video Processing · Electrical Eng. & Systems 2025-03-20 James Pope , Md Hassanuzzaman , William Chapman , Huw Day , Mingmar Sherpa , Omar Emara , Nirmala Adhikari , Ayush Joshi