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Crystallization of proteins, specifically proteins of medical relevance, is performed for various reasons such as to understand the protein structure and to design therapies. Obtaining kinetic constants in rate laws for nucleation and…

An accurate treatment of the multiphase interstellar medium (ISM) in hydrodynamic galaxy simulations requires that we follow not only the thermal evolution of the gas, but also the evolution of its chemical state, including its molecular…

Astrophysics of Galaxies · Physics 2015-06-18 Alexander J. Richings , Joop Schaye , Benjamin D. Oppenheimer

The discovery of inorganic crystal structures with targeted properties is a significant challenge in materials science. Generative models, especially state-of-the-art diffusion models, offer the promise of modeling complex data…

The purpose of continuum plasticity models is to efficiently predict the behavior of structures beyond their elastic limits. The purpose of multiscale materials science models, among them crystal plasticity models, is to understand the…

Materials Science · Physics 2020-12-18 Meijuan Zhang , K. Nguyen , Javier Segurado , Francisco J. Montans

We introduce CrystalFormer, a transformer-based autoregressive model specifically designed for space group-controlled generation of crystalline materials. By explicitly incorporating space group symmetry, CrystalFormer greatly reduces the…

Materials Science · Physics 2025-09-29 Zhendong Cao , Xiaoshan Luo , Jian Lv , Lei Wang

Using a remarkable mapping from the original (3+1)dimensional Skyrme model to the Sine-Gordon model, we construct the first analytic examples of Skyrmions as well as of Skyrmions--anti-Skyrmions bound states within a finite box in 3+1…

High Energy Physics - Theory · Physics 2017-10-11 P. D. Alvarez , F. Canfora , N. Dimakis , A. Paliathanasis

Comprehensive and confident identifications of metabolites and other chemicals in complex samples will revolutionize our understanding of the role these chemically diverse molecules play in biological systems. Despite recent advances,…

Magnetic cooling based on the magnetocaloric effect is a promising solid-state refrigeration technology for a wide range of applications in different temperature ranges. Previous studies have mostly focused on near room temperature (300 K)…

Materials Science · Physics 2024-03-06 Jiaoyue Yuan , Runqing Yang , Lokanath Patra , Bolin Liao

Single particle cryo-electron microscopy has become a critical tool in structural biology over the last decade, able to achieve atomic scale resolution in three dimensional models from hundreds of thousands of (noisy) two-dimensional…

Numerical Analysis · Mathematics 2023-07-19 Aaditya V. Rangan , Leslie Greengard

Hypothesis:Diffusion in confinement is an important fundamental problem with significant implications for applications of supported liquid phases. However, resolving the spatially dependent diffusion coefficient, parallel and perpendicular…

Context: The chemical composition of a molecular cloud changes dramatically as it collapses to form a low-mass protostar and circumstellar disk. Two-dimensional (2D) chemodynamical models are required to properly study this process. Aims:…

Astrophysics of Galaxies · Physics 2015-05-30 R. Visser , S. D. Doty , E. F. van Dishoeck

We demonstrate the measurement and manipulation of the temperature of cold CO molecules in a microchip environment. Through the use of time-resolved spatial imaging, we are able to observe the phase-space distribution of the molecules, and…

Protein language models (PLMs) have shown promise in improving the understanding of protein sequences, contributing to advances in areas such as function prediction and protein engineering. However, training these models from scratch…

Machine Learning · Computer Science 2024-12-19 Shivasankaran Vanaja Pandi , Bharath Ramsundar

Laser flash melting and revitrification experiments have recently improved the time resolution of cryo-electron microscopy (cryo-EM) to the microsecond timescale, making it fast enough to observe many of the protein motions that are…

Instrumentation and Detectors · Physics 2026-05-19 Wyatt A. Curtis , Constantin R. Krüger , Axel P. Tracol Gavard , Jakub Wenz , Marcel Drabbels , Ulrich J. Lorenz

Efficiently generating energetically stable crystal structures has long been a challenge in material design, primarily due to the immense arrangement of atoms in a crystal lattice. To facilitate the discovery of stable material, we present…

Artificial Intelligence · Computer Science 2025-09-30 Zhelin Li , Rami Mrad , Runxian Jiao , Guan Huang , Jun Shan , Shibing Chu , Yuanping Chen

The study of the chemical composition of the interstellar medium (ISM) requires a strong synergy between laboratory astrophysics, modeling, and observations. In particular, astrochemical models have been developed for decades now and…

Astrophysics of Galaxies · Physics 2024-07-24 V. Wakelam , P. Gratier , J. -C. Loison , K. M. Hickson , J. Penguen , A. Mechineau

The issue of ice accumulation at low-temperature circumstances causes multiple problems and serious damages in many civil infrastructures which substantially influence human daily life. However, despite the significant consideration in…

Chemical Physics · Physics 2020-11-24 Amir Afshar , Dong Meng

Partitioning of (bio)materials in polymeric mixtures is a key phenomenon both in cellular environments, as well as in industrial applications. In cells, several macromolecules are suspended within different biomolecular phases. On the other…

Soft Condensed Matter · Physics 2025-10-15 Vikki Anand Varma , Alberto Scacchi

The high metallicity of the intra-cluster medium (ICM) is generally interpreted on the base of the galactic wind scenario for elliptical galaxies. In this framework, we develop a toy-model to follow the chemical evolution of the ICM,…

Astrophysics · Physics 2007-05-23 L. Portinari , A. Moretti , C. Chiosi

Proteins are the fundamental macromolecules that play diverse and crucial roles in all living matter and have tremendous implications in healthcare, manufacturing, and biotechnology. Their functions are largely determined by the sequences…

Biomolecules · Quantitative Biology 2024-09-17 Boqiao Lai
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