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Understanding how cortex, subcortex and cerebellum integrate is a major challenge for neuroscience, however, studies of the brain's structural connectivity have mostly focused on cortico-cortical links. Here, we used diffusion imaging to…

Neurons and Cognition · Quantitative Biology 2025-10-21 Julian Schulte , Mario Senden , Gustavo Deco , Xenia Kobeleva , Gorka Zamora-López

Diffusion tractography in brain connectomics often involves tracing axonal trajectories across gray-white matter boundaries in gyral blades of complex cortical convolutions. To date, gyral bias is observed in most tractography algorithms…

Neurons and Cognition · Quantitative Biology 2019-04-15 Ye Wu , Yoonmi Hong , Yuanjing Feng , Dinggang Shen , Pew-Thian Yap

Brain networks can be defined and explored through their connectivity. Here, we analyzed the relationship between structural connectivity (SC) across 2,514 regions that cover the entire brain and brainstem, and their dynamic functional…

In summary of the research findings presented in this paper, various brain regions are correlated with vocabulary and vocabulary acquisition. Semantic associations for vocabulary seem to be located near brain areas that vary according to…

Neurons and Cognition · Quantitative Biology 2016-12-01 Tom A. F. Anderson , C. -H. Ruan

The organization and connectivity of the arcuate fasciculus (AF) in nonhuman primates remain contentious, especially concerning how its anatomy diverges from that of humans. Here, we combined cross-scale single-neuron tracing - using…

Brain function emerges from coordinated activity across anatomically connected regions, where structural connectivity (SC) -- the network of white matter pathways - provides the physical substrate for functional connectivity (FC) -- the…

Neurons and Cognition · Quantitative Biology 2025-07-09 Sam Frank Kelemen , Joaquín Gõni , Sérgio Pequito , Arian Ashourvan

One of the central problems in neuroscience is understanding how brain structure relates to function. Naively one can relate the direct connections of white matter fiber tracts between brain regions of interest (ROIs) to the increased…

Neurons and Cognition · Quantitative Biology 2023-08-30 Haoming Yang , Steven Winter , Zhengwu Zhang , David Dunson

First-episode schizophrenia (FES) results in abnormality of brain connectivity at different levels. Despite some successful findings on functional and structural connectivity of FES, relatively few studies have been focused on morphological…

Neurons and Cognition · Quantitative Biology 2022-12-27 Mowen Yin , Weikai Huang , Zhichao Liang , Quanying Liu , Xiaoying Tang

Unraveling how macroscopic cognitive phenotypes emerge from microscopic neuronal connectivity remains one of the core pursuits of neuroscience. To this end, researchers typically leverage multi-modal information from structural connectivity…

Artificial Intelligence · Computer Science 2026-02-03 Tianhao Huang , Guanghui Min , Zhenyu Lei , Aiying Zhang , Chen Chen

This study proposes an approach to estimate the functional localization and connectivity from CBF and BOLD signals simultaneously measured by ASL (arterial spin labeling) MRI, especially using exploratory Structural Equation Modeling…

Neurons and Cognition · Quantitative Biology 2017-04-11 Jiancheng Zhuang

White matter tract microstructure has been shown to influence neuropsychological scores of cognitive performance. However, prediction of these scores from white matter tract data has not been attempted. In this paper, we propose a…

Computer Vision and Pattern Recognition · Computer Science 2022-07-07 Yuqian Chen , Fan Zhang , Chaoyi Zhang , Tengfei Xue , Leo R. Zekelman , Jianzhong He , Yang Song , Nikos Makris , Yogesh Rathi , Alexandra J. Golby , Weidong Cai , Lauren J. O'Donnell

Structural and functional MRI studies of patients with post-stroke language deficits have contributed substantially to our understanding of how cognitive-behavioral impairments relate to the location of structural damage and to the…

Neurons and Cognition · Quantitative Biology 2016-10-14 Joseph C. Griffis , Rodolphe Nenert , Jane B. Allendorfer , Jerzy P. Szaflarski

The human braingraph, or connectome is a description of the connections of the brain: the nodes of the graph correspond to small areas of the gray matter, and two nodes are connected by an edge if a diffusion MRI-based workflow finds fibers…

Neurons and Cognition · Quantitative Biology 2015-07-02 Csaba Kerepesi , Balázs Szalkai , Bálint Varga , Vince Grolmusz

In the applications of the graph theory it is unusual that one considers numerous, pairwise different graphs on the very same set of vertices. In the case of human braingraphs or connectomes, however, this is the standard situation: the…

Neurons and Cognition · Quantitative Biology 2016-05-06 Csaba Kerepesi , Balint Varga , Balazs Szalkai , Vince Grolmusz

The speech signal conveys information on different time scales from short time scale or segmental, associated to phonological and phonetic information to long time scale or supra segmental, associated to syllabic and prosodic information.…

Computation and Language · Computer Science 2016-09-16 Milos Cernak , Afsaneh Asaei , Hervé Bourlard

In studying structural inter-connections in the human brain, it is common to first estimate fiber bundles connecting different regions of the brain relying on diffusion MRI. These fiber bundles act as highways for neural activity and…

Applications · Statistics 2016-12-06 Zhengwu Zhang , Maxime Descoteaux , David B. Dunson

Understanding how humans process natural language has long been a vital research direction. The field of natural language processing (NLP) has recently experienced a surge in the development of powerful language models. These models have…

Computation and Language · Computer Science 2023-11-20 Zhengqi He , Taro Toyoizumi

Inter-subject registration of cortical areas is necessary in functional imaging (fMRI) studies for making inferences about equivalent brain function across a population. However, many high-level visual brain areas are defined as peaks of…

Neurons and Cognition · Quantitative Biology 2016-06-09 Marius Cătălin Iordan , Armand Joulin , Diane M. Beck , Li Fei-Fei

Recent work has shown that multimodal association areas-including frontal, temporal and parietal cortex-are focal points of functional network reconfiguration during human learning and performance of cognitive tasks. On the other hand,…

Neurons and Cognition · Quantitative Biology 2016-10-12 F. A. Soto , D. S. Bassett , F. G. Ashby

This paper investigates prefrontal cortex (PFC) functional connectivity based on synchronized electrical and hemodynamic responses associated with mental stress. The electrical response was based on alpha rhythmic of Electroencephalography…

Neurons and Cognition · Quantitative Biology 2021-03-09 Fares Al-Shargie
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