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Artificial intelligence (AI) systems utilizing deep neural networks (DNNs) and machine learning (ML) algorithms are widely used for solving important problems in bioinformatics, biomedical informatics, and precision medicine. However,…

Quantitative Methods · Quantitative Biology 2023-02-24 Md. Rezaul Karim , Tanhim Islam , Oya Beyan , Christoph Lange , Michael Cochez , Dietrich Rebholz-Schuhmann , Stefan Decker

As the manufacturing industry advances with sensor integration and automation, the opaque nature of deep learning models in machine learning poses a significant challenge for fault detection and diagnosis. And despite the related predictive…

Artificial Intelligence · Computer Science 2024-06-11 Ahmed Maged , Salah Haridy , Herman Shen

Nowadays, deep neural networks are widely used in mission critical systems such as healthcare, self-driving vehicles, and military which have direct impact on human lives. However, the black-box nature of deep neural networks challenges its…

Computer Vision and Pattern Recognition · Computer Science 2020-06-24 Arun Das , Paul Rad

There has recently been a surge of work in explanatory artificial intelligence (XAI). This research area tackles the important problem that complex machines and algorithms often cannot provide insights into their behavior and thought…

Artificial Intelligence · Computer Science 2019-02-05 Leilani H. Gilpin , David Bau , Ben Z. Yuan , Ayesha Bajwa , Michael Specter , Lalana Kagal

XAI refers to the techniques and methods for building AI applications which assist end users to interpret output and predictions of AI models. Black box AI applications in high-stakes decision-making situations, such as medical domain have…

The integration of artificial intelligence (AI) into medicine is remarkable, offering advanced diagnostic and therapeutic possibilities. However, the inherent opacity of complex AI models presents significant challenges to their clinical…

Computer Vision and Pattern Recognition · Computer Science 2025-09-23 Binbin Wen , Yihang Wu , Tareef Daqqaq , Ahmad Chaddad

Artificial Intelligence in Medicine has made significant progress with emerging applications in medical imaging, patient care, and other areas. While these applications have proven successful in retrospective studies, very few of them were…

Artificial Intelligence · Computer Science 2023-08-11 Nicoletta Prentzas , Antonis Kakas , Constantinos S. Pattichis

Artificial intelligence models encounter significant challenges due to their black-box nature, particularly in safety-critical domains such as healthcare, finance, and autonomous vehicles. Explainable Artificial Intelligence (XAI) addresses…

Artificial Intelligence · Computer Science 2025-03-14 Melkamu Mersha , Khang Lam , Joseph Wood , Ali AlShami , Jugal Kalita

Explainable Artificial Intelligence (XAI) addresses the growing need for transparency and interpretability in AI systems, enabling trust and accountability in decision-making processes. This book offers a comprehensive guide to XAI,…

Artificial intelligence (AI), particularly machine learning and deep learning models, has significantly impacted bioinformatics research by offering powerful tools for analyzing complex biological data. However, the lack of interpretability…

Artificial Intelligence · Computer Science 2023-12-12 Zhongliang Zhou , Mengxuan Hu , Mariah Salcedo , Nathan Gravel , Wayland Yeung , Aarya Venkat , Dongliang Guo , Jielu Zhang , Natarajan Kannan , Sheng Li

Explainable artificial intelligence (XAI) plays an indispensable role in demystifying the decision-making processes of AI, especially within the healthcare industry. Clinicians rely heavily on detailed reasoning when making a diagnosis,…

Computer Vision and Pattern Recognition · Computer Science 2024-03-26 Anna Stubbin , Thompson Chyrikov , Jim Zhao , Christina Chajo

With an increase in deep learning-based methods, the call for explainability of such methods grows, especially in high-stakes decision making areas such as medical image analysis. This survey presents an overview of eXplainable Artificial…

Image and Video Processing · Electrical Eng. & Systems 2022-05-06 Bas H. M. van der Velden , Hugo J. Kuijf , Kenneth G. A. Gilhuijs , Max A. Viergever

Artificial intelligence has become pervasive across disciplines and fields, and biomedical image and signal processing is no exception. The growing and widespread interest on the topic has triggered a vast research activity that is…

Machine Learning · Computer Science 2022-07-12 Guang Yang , Arvind Rao , Christine Fernandez-Maloigne , Vince Calhoun , Gloria Menegaz

There is a disconnect between explanatory artificial intelligence (XAI) methods and the types of explanations that are useful for and demanded by society (policy makers, government officials, etc.) Questions that experts in artificial…

Artificial Intelligence · Computer Science 2019-01-23 Leilani H. Gilpin , Cecilia Testart , Nathaniel Fruchter , Julius Adebayo

Explainable Artificial Intelligence (XAI) is essential for building advanced machine learning-powered applications, especially in critical domains such as medical diagnostics or autonomous driving. Legal, business, and ethical requirements…

Human-Computer Interaction · Computer Science 2024-10-17 Tobias Labarta , Elizaveta Kulicheva , Ronja Froelian , Christian Geißler , Xenia Melman , Julian von Klitzing

The growing adoption of artificial intelligence in healthcare has raised concerns about the transparency and trustworthiness of AI-driven medical diagnosis systems. Many existing models operate as black boxes, limiting clinicians' ability…

Human-Computer Interaction · Computer Science 2026-04-21 Altynbek Seitenov , Ainur Nurzhanova , Azhar Bekbussinova , Yerassyl Bolatkan

The remarkable success of deep learning has prompted interest in its application to medical imaging diagnosis. Even though state-of-the-art deep learning models have achieved human-level accuracy on the classification of different types of…

Image and Video Processing · Electrical Eng. & Systems 2023-09-20 Cristiano Patrício , João C. Neves , Luís F. Teixeira

Explainable Artificial Intelligence (XAI) techniques are frequently required by users in many AI systems with the goal of understanding complex models, their associated predictions, and gaining trust. While suitable for some specific tasks…

Human-Computer Interaction · Computer Science 2023-03-22 Savio Rozario , George Čevora

The remarkable advancements in Deep Learning (DL) algorithms have fueled enthusiasm for using Artificial Intelligence (AI) technologies in almost every domain; however, the opaqueness of these algorithms put a question mark on their…

Machine Learning · Computer Science 2021-01-12 F. Hussain , R. Hussain , E. Hossain

The unprecedented performance of machine learning models in recent years, particularly Deep Learning and transformer models, has resulted in their application in various domains such as finance, healthcare, and education. However, the…

Human-Computer Interaction · Computer Science 2023-12-20 Milad Rogha
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