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Interpretability is a pressing issue for machine learning. Common approaches to interpretable machine learning constrain interactions between features of the input, rendering the effects of those features on a model's output comprehensible…

Machine Learning · Computer Science 2023-05-11 Kieran A. Murphy , Dani S. Bassett

Explaining recommendations enables users to understand whether recommended items are relevant to their needs and has been shown to increase their trust in the system. More generally, if designing explainable machine learning models is key…

Machine Learning · Computer Science 2020-08-27 Darius Afchar , Romain Hennequin

Ante-hoc interpretability has become the holy grail of explainable artificial intelligence for high-stakes domains such as healthcare; however, this notion is elusive, lacks a widely-accepted definition and depends on the operational…

Machine Learning · Computer Science 2023-07-11 Kacper Sokol , Julia E. Vogt

Predictive models are omnipresent in automated and assisted decision making scenarios. But for the most part they are used as black boxes which output a prediction without understanding partially or even completely how different features…

Information Retrieval · Computer Science 2018-07-02 Jaspreet Singh , Avishek Anand

In many scenarios, the interpretability of machine learning models is a highly required but difficult task. To explain the individual predictions of such models, local model-agnostic approaches have been proposed. However, the process…

Machine Learning · Statistics 2025-10-22 Gianluigi Lopardo , Frederic Precioso , Damien Garreau

A wide variety of model explanation approaches have been proposed in recent years, all guided by very different rationales and heuristics. In this paper, we take a new route and cast interpretability as a statistical inference problem. We…

Machine Learning · Computer Science 2024-01-01 Hugo Henri Joseph Senetaire , Damien Garreau , Jes Frellsen , Pierre-Alexandre Mattei

The use of sophisticated machine learning models for critical decision making is faced with a challenge that these models are often applied as a "black-box". This has led to an increased interest in interpretable machine learning, where…

Artificial Intelligence · Computer Science 2020-07-22 Catarina Moreira , Yu-Liang Chou , Mythreyi Velmurugan , Chun Ouyang , Renuka Sindhgatta , Peter Bruza

Deep learning-based AI models have been extensively applied in genomics, achieving remarkable success across diverse applications. As these models gain prominence, there exists an urgent need for interpretability methods to establish…

Genomics · Quantitative Biology 2025-05-16 Chenyu Wang , Chaoying Zuo , Zihan Su , Yuhang Xing , Lu Li , Maojun Wang , Zeyu Zhang

For AI systems to garner widespread public acceptance, we must develop methods capable of explaining the decisions of black-box models such as neural networks. In this work, we identify two issues of current explanatory methods. First, we…

Computation and Language · Computer Science 2019-12-06 Oana-Maria Camburu , Eleonora Giunchiglia , Jakob Foerster , Thomas Lukasiewicz , Phil Blunsom

In healthcare there is a pursuit for employing interpretable algorithms to assist healthcare professionals in several decision scenarios. Following the Predictive, Descriptive and Relevant (PDR) framework, the definition of interpretable…

The interpretability of machine learning models has gained increasing attention, particularly in scientific domains where high precision and accountability are crucial. This research focuses on distinguishing between two critical data…

Machine Learning · Computer Science 2024-07-02 Jiajun Zhu , Siqi Miao , Rex Ying , Pan Li

Interpretability is highly desired for deep neural network-based classifiers, especially when addressing high-stake decisions in medical imaging. Commonly used post-hoc interpretability methods have the limitation that they can produce…

Image and Video Processing · Electrical Eng. & Systems 2024-01-04 Sourya Sengupta , Mark A. Anastasio

Understanding why machine learning models behave the way they do empowers both system designers and end-users in many ways: in model selection, feature engineering, in order to trust and act upon the predictions, and in more intuitive user…

Machine Learning · Statistics 2016-06-20 Marco Tulio Ribeiro , Sameer Singh , Carlos Guestrin

Machine learning models that first learn a representation of a domain in terms of human-understandable concepts, then use it to make predictions, have been proposed to facilitate interpretation and interaction with models trained on…

Machine Learning · Computer Science 2020-12-08 Isaac Lage , Finale Doshi-Velez

There is a need of ensuring machine learning models that are interpretable. Higher interpretability of the model means easier comprehension and explanation of future predictions for end-users. Further, interpretable machine learning models…

Machine Learning · Computer Science 2020-08-17 Gregor Stiglic , Primoz Kocbek , Nino Fijacko , Marinka Zitnik , Katrien Verbert , Leona Cilar

Post-hoc interpretability methods play a critical role in explainable artificial intelligence (XAI), as they pinpoint portions of data that a trained deep learning model deemed important to make a decision. However, different post-hoc…

Machine Learning · Computer Science 2024-07-30 Jiawen Wei , Hugues Turbé , Gianmarco Mengaldo

The increasing use of deep learning across various domains highlights the importance of understanding the decision-making processes of these black-box models. Recent research focusing on the decision boundaries of deep classifiers, relies…

Machine Learning · Computer Science 2024-08-13 Inês Gomes , Luís F. Teixeira , Jan N. van Rijn , Carlos Soares , André Restivo , Luís Cunha , Moisés Santos

Deep learning methods are highly accurate, yet their opaque decision process prevents them from earning full human trust. Concept-based models aim to address this issue by learning tasks based on a set of human-understandable concepts.…

Deep learning models often suffer from a lack of interpretability due to polysemanticity, where individual neurons are activated by multiple unrelated semantics, resulting in unclear attributions of model behavior. Recent advances in…

Machine Learning · Computer Science 2024-10-30 Qi Zhang , Yifei Wang , Jingyi Cui , Xiang Pan , Qi Lei , Stefanie Jegelka , Yisen Wang

Understanding the predictions made by deep learning models remains a central challenge, especially in high-stakes applications. A promising approach is to equip models with the ability to answer counterfactual questions -- hypothetical…

Machine Learning · Computer Science 2025-10-28 Inwoo Hwang , Yushu Pan , Elias Bareinboim