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Hasse diagrams provide a principled means for visualizing the structure of statistical designs constructed by crossing and nesting of experimental factors. They have long been applied for automated construction of linear models and their…

Applications · Statistics 2019-12-19 Hans-Michael Kaltenbach

Simulation studies are computer experiments that involve creating data by pseudorandom sampling. The key strength of simulation studies is the ability to understand the behaviour of statistical methods because some 'truth' (usually some…

Methodology · Statistics 2019-01-18 Tim P Morris , Ian R White , Michael J Crowther

Design of experiments (DOE) is playing an essential role in learning and improving a variety of objects and processes. The article discusses the application of unsupervised machine learning to support the pragmatic designs of complex…

Machine Learning · Computer Science 2021-10-07 Alex Glushkovsky

The challenge of optimal design of experiments (DOE) pervades materials science, physics, chemistry, and biology. Bayesian optimization has been used to address this challenge in vast sample spaces, although it requires framing experimental…

Many safety-critical scientific and engineering systems evolve according to differential-algebraic equations (DAEs), where dynamical behavior is constrained by physical laws and admissibility conditions. In practice, these systems operate…

Machine Learning · Computer Science 2026-04-14 Minxing Zheng , Zewei Deng , Liyan Xie , Shixiang Zhu

Frequentist statistical methods, such as hypothesis testing, are standard practice in papers that provide benchmark comparisons. Unfortunately, these methods have often been misused, e.g., without testing for their statistical test…

Methodology · Statistics 2021-05-18 David Issa Mattos , Jan Bosch , Helena Holmström Olsson

Model-based design of experiments (MBDOE) is essential for efficient parameter estimation in nonlinear dynamical systems. However, conventional adaptive MBDOE requires costly posterior inference and design optimization between each…

Machine Learning · Statistics 2026-03-25 Arno Strouwen , Sebastian Micluţa-Câmpeanu

Factorial designs are frequently used in different fields of science, e.g. psychological, medical or biometric studies. Standard approaches, as the ANOVA $F$-test, make different assumptions on the distribution of the error terms, the…

Methodology · Statistics 2018-02-21 Maria Umlauft

Materials design problems often require optimizing multiple variables, rendering full factorial exploration impractical. Design of experiment (DOE) methods, such as Taguchi technique, are commonly used to efficiently sample the design space…

Machine Learning · Computer Science 2025-06-05 Shyam Prabhu , P Akshay Kumar , Antov Selwinston , Pavan Taduvai , Shreya Bairi , Rohit Batra

The controller design of the so-called "difference algebraic equation" (DAE) systems that are frequently shown in industrial processes, tend to be challenging because of the combination of algebraic equations and high state dimensions. In…

Systems and Control · Computer Science 2017-03-16 Fei Chen

The increasing prevalence of rich sources of data and the availability of electronic medical record databases and electronic registries opens tremendous opportunities for enhancing medical research. For example, controlled trials are…

Methodology · Statistics 2015-09-23 Liwen Ouyang , Daniel W. Apley , Sanjay Mehrotra

Simulation experiments are typically conducted repeatedly during the model development process, for example, to re-validate if a behavioral property still holds after several model changes. Approaches for automatically reusing and…

Computational Engineering, Finance, and Science · Computer Science 2021-09-15 Pia Wilsdorf , Anja Wolpers , Jason Hilton , Fiete Haack , Adelinde M. Uhrmacher

In the context of high penetration of renewables, the need to build dynamic models of power system components based on accessible measurement data has become urgent. To address this challenge, firstly, a neural ordinary differential…

Systems and Control · Electrical Eng. & Systems 2022-08-02 Tannan Xiao , Ying Chen , Shaowei Huang , Tirui He , Huizhe Guan

Empirical design in reinforcement learning is no small task. Running good experiments requires attention to detail and at times significant computational resources. While compute resources available per dollar have continued to grow…

Machine Learning · Computer Science 2024-10-30 Andrew Patterson , Samuel Neumann , Martha White , Adam White

The ever-increasing complexity of software systems makes them hard to comprehend, predict and tune due to emergent properties and non-deterministic behaviour. Complexity arises from the size of software systems and the wide variety of…

Software Engineering · Computer Science 2010-07-01 Aled Sage

Design of Experiments (DoE) is a relevant class to undergraduate students in the sciences, because it teaches them how to plan, conduct, and analyze experiments. In the literature on DoE, there are several contributions to its pedagogy,…

Other Statistics · Statistics 2024-07-31 Alan R. Vazquez , Xiaocong Xuan

Simulation methods are among the most ubiquitous methodological tools in statistical science. In particular, statisticians often is simulation to explore properties of statistical functionals in models for which developed statistical theory…

Methodology · Statistics 2023-08-22 Tyrel Stokes , Ian Shrier , Russell Steele

Computational models are powerful tools for understanding human cognition and behavior. They let us express our theories clearly and precisely, and offer predictions that can be subtle and often counter-intuitive. However, this same…

Discriminant analysis (DA) is one of the most popular methods for classification due to its conceptual simplicity, low computational cost, and often solid performance. In its standard form, DA uses the arithmetic mean and sample covariance…

Methodology · Statistics 2026-05-12 Mia Hubert , Jakob Raymaekers , Peter J. Rousseeuw

Computer models are used as replacements for physical experiments in a large variety of applications. Nevertheless, direct use of the computer model for the ultimate scientific objective is often limited by the complexity and cost of the…

Methodology · Statistics 2019-07-03 Sonja Surjanovic , William J. Welch
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