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Segment anything model (SAM) has emerged as the leading approach for zero-shot learning in segmentation tasks, offering the advantage of avoiding pixel-wise annotations. It is particularly appealing in medical image segmentation, where the…

Image and Video Processing · Electrical Eng. & Systems 2023-12-29 Ziyi Huang , Hongshan Liu , Haofeng Zhang , Xueshen Li , Haozhe Liu , Fuyong Xing , Andrew Laine , Elsa Angelini , Christine Hendon , Yu Gan

Segmentation is an important analysis task for biomedical images, enabling the study of individual organelles, cells or organs. Deep learning has massively improved segmentation methods, but challenges remain in generalization to new…

Computer Vision and Pattern Recognition · Computer Science 2025-06-03 Carolin Teuber , Anwai Archit , Constantin Pape

The problem of inter-rater variability is often discussed in the context of manual labeling of medical images. The emergence of data-driven approaches such as Deep Neural Networks (DNNs) brought this issue of raters' disagreement to the…

Image and Video Processing · Electrical Eng. & Systems 2020-06-02 Or Shwartzman , Harel Gazit , Ilan Shelef , Tammy Riklin-Raviv

Semi-supervised learning (SSL) has become a promising solution to alleviate the annotation burden of deep learning-based medical image segmentation models. While recent advances in foundation model-driven SSL have pushed the boundary to…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Yichi Zhang , Le Xue , Bichun Xu , Judong Luo , Zhigang Wu , Yu Fu , Zixin Hu , Yuan Cheng , Yuan Qi

Although active learning (AL) in segmentation tasks enables experts to annotate selected regions of interest (ROIs) instead of entire images, it remains highly challenging, labor-intensive, and cognitively demanding due to the blurry and…

Computer Vision and Pattern Recognition · Computer Science 2025-11-19 Md Shazid Islam , Shreyangshu Bera , Sudipta Paul , Amit K. Roy-Chowdhury

Deep neural networks (DNNs) have demonstrated exceptional performance across various image segmentation tasks. However, the process of preparing datasets for training segmentation DNNs is both labor-intensive and costly, as it typically…

Computer Vision and Pattern Recognition · Computer Science 2025-01-24 Yixin Zhang , Shen Zhao , Hanxue Gu , Maciej A. Mazurowski

Reliable classification and detection of certain medical conditions, in images, with state-of-the-art semantic segmentation networks, require vast amounts of pixel-wise annotation. However, the public availability of such datasets is…

Computer Vision and Pattern Recognition · Computer Science 2023-03-17 Erik Ostrowski , Bharath Srinivas Prabakaran , Muhammad Shafique

Recent advances in deep learning have greatly facilitated the automated segmentation of ultrasound images, which is essential for nodule morphological analysis. Nevertheless, most existing methods depend on extensive and precise annotations…

Computer Vision and Pattern Recognition · Computer Science 2024-04-24 Xingyue Zhao , Zhongyu Li , Xiangde Luo , Peiqi Li , Peng Huang , Jianwei Zhu , Yang Liu , Jihua Zhu , Meng Yang , Shi Chang , Jun Dong

Semantic segmentation is a critical step in automated image interpretation and analysis where pixels are classified into one or more predefined semantically meaningful classes. Deep learning approaches for semantic segmentation rely on…

Computer Vision and Pattern Recognition · Computer Science 2023-07-10 Tushar Kataria , Beatrice Knudsen , Shireen Elhabian

Instance segmentation in 3D images is a fundamental task in biomedical image analysis. While deep learning models often work well for 2D instance segmentation, 3D instance segmentation still faces critical challenges, such as insufficient…

Computer Vision and Pattern Recognition · Computer Science 2018-07-02 Zhuo Zhao , Lin Yang , Hao Zheng , Ian H. Guldner , Siyuan Zhang , Danny Z. Chen

Deep learning-based object detectors have achieved impressive performance in microscopy imaging, yet their confidence estimates often lack calibration, limiting their reliability for biomedical applications. In this work, we introduce a new…

Computer Vision and Pattern Recognition · Computer Science 2026-02-02 Francesco Campi , Lucrezia Tondo , Ekin Karabati , Johannes Betge , Marie Piraud

Precise delineation of multiple organs or abnormal regions in the human body from medical images plays an essential role in computer-aided diagnosis, surgical simulation, image-guided interventions, and especially in radiotherapy treatment…

Image and Video Processing · Electrical Eng. & Systems 2024-11-19 Shiman Li , Haoran Wang , Yucong Meng , Chenxi Zhang , Zhijian Song

Accurate annotation of endoscopic videos is essential yet time-consuming, particularly for challenging datasets such as dysplasia in Barrett's esophagus, where the affected regions are irregular and lack clear boundaries. Semi-automatic…

Computer Vision and Pattern Recognition · Computer Science 2026-02-26 Lokesha Rasanjalee , Jin Lin Tan , Dileepa Pitawela , Rajvinder Singh , Hsiang-Ting Chen

Semantic segmentation is a crucial task in biomedical image processing, which recent breakthroughs in deep learning have allowed to improve. However, deep learning methods in general are not yet widely used in practice since they require…

Computer Vision and Pattern Recognition · Computer Science 2019-07-12 Melanie Lubrano di Scandalea , Christian S. Perone , Mathieu Boudreau , Julien Cohen-Adad

Traditional supervised 3D medical image segmentation models need voxel-level annotations, which require huge human effort, time, and cost. Semi-supervised learning (SSL) addresses this limitation of supervised learning by facilitating…

Image and Video Processing · Electrical Eng. & Systems 2024-07-09 Suruchi Kumari , Aryan Das , Swalpa Kumar Roy , Indu Joshi , Pravendra Singh

In clinical medicine, precise image segmentation can provide substantial support to clinicians. However, obtaining high-quality segmentation typically demands extensive pixel-level annotations, which are labor-intensive and expensive.…

Computer Vision and Pattern Recognition · Computer Science 2025-10-30 Tao Wang , Xinlin Zhang , Zhenxuan Zhang , Yuanbo Zhou , Yuanbin Chen , Longxuan Zhao , Chaohui Xu , Shun Chen , Guang Yang , Tong Tong

Pre-training a recognition model with contrastive learning on a large dataset of unlabeled data has shown great potential to boost the performance of a downstream task, e.g., image classification. However, in domains such as medical…

Computer Vision and Pattern Recognition · Computer Science 2021-08-24 Jizong Peng , Ping Wang , Chrisitian Desrosiers , Marco Pedersoli

Cold-Start Active Learning (CSAL) aims to select informative samples for annotation without prior knowledge, which is important for improving annotation efficiency and model performance under a limited annotation budget in medical image…

Computer Vision and Pattern Recognition · Computer Science 2025-10-13 Ning Zhu , Xiaochuan Ma , Shaoting Zhang , Guotai Wang

Semantic segmentation of medical images is a crucial step for the quantification of healthy anatomy and diseases alike. The majority of the current state-of-the-art segmentation algorithms are based on deep neural networks and rely on large…

Computer Vision and Pattern Recognition · Computer Science 2018-07-13 Yigit B. Can , Krishna Chaitanya , Basil Mustafa , Lisa M. Koch , Ender Konukoglu , Christian F. Baumgartner

Noisy labels can significantly affect the performance of deep neural networks (DNNs). In medical image segmentation tasks, annotations are error-prone due to the high demand in annotation time and in the annotators' expertise. Existing…

Image and Video Processing · Electrical Eng. & Systems 2023-08-08 Jiachen Yao , Yikai Zhang , Songzhu Zheng , Mayank Goswami , Prateek Prasanna , Chao Chen