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The solution of inverse problems is crucial in various fields such as medicine, biology, and engineering, where one seeks to find a solution from noisy observations. These problems often exhibit non-uniqueness and ill-posedness, resulting…

Numerical Analysis · Mathematics 2024-10-21 Markus Haltmeier , Richard Kowar , Markus Tiefenthaler

Diverse inverse problems in imaging can be cast as variational problems composed of a task-specific data fidelity term and a regularization term. In this paper, we propose a novel learnable general-purpose regularizer exploiting recent…

Optimization and Control · Mathematics 2020-02-19 Erich Kobler , Alexander Effland , Karl Kunisch , Thomas Pock

In this work, we are concerned with the diffusive optical tomography (DOT) problem in the case when only one or two pairs of Cauchy data is available. We propose a simple and efficient direct sampling method (DSM) to locate inhomogeneities…

Mathematical Physics · Physics 2014-10-07 Yat Tin Chow , Kazufumi Ito , Keji Liu , Jun Zou

The importance of regularization has been well established in image reconstruction -- which is the computational inversion of imaging forward model -- with applications including deconvolution for microscopy, tomographic reconstruction,…

Image and Video Processing · Electrical Eng. & Systems 2021-06-29 Sanjay Viswanath , Manu Ghulyani , Muthuvel Arigovindan

Inverse problems arise in a variety of imaging applications including computed tomography, non-destructive testing, and remote sensing. The characteristic features of inverse problems are the non-uniqueness and instability of their…

Numerical Analysis · Mathematics 2020-06-09 Markus Haltmeier , Linh V. Nguyen

In this paper we present a generalized Deep Learning-based approach for solving ill-posed large-scale inverse problems occuring in medical image reconstruction. Recently, Deep Learning methods using iterative neural networks and cascaded…

Image and Video Processing · Electrical Eng. & Systems 2020-08-26 Andreas Kofler , Markus Haltmeier , Tobias Schaeffter , Marc Kachelrieß , Marc Dewey , Christian Wald , Christoph Kolbitsch

Our world is full of physics-driven data where effective mappings between data manifolds are desired. There is an increasing demand for understanding combined model-based and data-driven methods. We propose a nonlinear, learned singular…

Machine Learning · Computer Science 2020-09-30 Yoeri E. Boink , Christoph Brune

Regularization plays a pivotal role in integrating prior information into inverse problems. While many deep learning methods have been proposed to solve inverse problems, determining where to apply regularization remains a crucial…

Numerical Analysis · Mathematics 2024-03-22 Ke Chen , Chunmei Wang , Haizhao Yang

Numerous diffusion model (DM)-based methods have been proposed for solving inverse imaging problems. Among these, a recent line of work has demonstrated strong performance by formulating sampling as an optimization procedure that enforces…

Image and Video Processing · Electrical Eng. & Systems 2025-11-19 Shijun Liang , Ismail Alkhouri , Qing Qu , Rongrong Wang , Saiprasad Ravishankar

Diffusion tensor imaging (DTI) holds significant importance in clinical diagnosis and neuroscience research. However, conventional model-based fitting methods often suffer from sensitivity to noise, leading to decreased accuracy in…

Computer Vision and Pattern Recognition · Computer Science 2024-09-05 Jialong Li , Zhicheng Zhang , Yunwei Chen , Qiqi Lu , Ye Wu , Xiaoming Liu , QianJin Feng , Yanqiu Feng , Xinyuan Zhang

The deep image prior (DIP) is a well-established unsupervised deep learning method for image reconstruction; yet it is far from being flawless. The DIP overfits to noise if not early stopped, or optimized via a regularized objective. We…

Image and Video Processing · Electrical Eng. & Systems 2023-05-16 Marco Nittscher , Michael Lameter , Riccardo Barbano , Johannes Leuschner , Bangti Jin , Peter Maass

Solving inverse problems requires appropriate regularization techniques to ensure well-posedness and stability. In recent years, denoiser-driven methods have emerged as effective regularization strategies, achieving state-of-the-art…

Numerical Analysis · Mathematics 2026-04-23 Harshit Bajpai , Ankik Kumar Giri , Tim Jahn , Abhinav Jha

Recently, generative diffusion priors have made huge strides as inverse problem solvers, including the ability to be adapted for inference on out-of-distribution data. Concurrently, implicit neural representations (INRs) have emerged as…

Image and Video Processing · Electrical Eng. & Systems 2026-03-12 Maliha Hossain , Haley Duba-Sullivan , Amirkoushyar Ziabari

Low-dose CT imaging requires reconstruction from noisy indirect measurements which can be defined as an ill-posed linear inverse problem. In addition to conventional FBP method in CT imaging, recent compressed sensing based methods exploit…

Image and Video Processing · Electrical Eng. & Systems 2025-11-14 Mehmet Ozan Unal , Metin Ertas , Isa Yildirim

Building on the well-known total-variation (TV), this paper develops a general regularization technique based on nonlinear isotropic diffusion (NID) for inverse problems with piecewise smooth solutions. The novelty of our approach is to be…

Numerical Analysis · Mathematics 2021-08-25 Bernadette N. Hahn , Gael Rigaud , Richard Schmähl

Distributions measured in high energy physics experiments are usually distorted and/or transformed by various detector effects. A regularization method for unfolding these distributions is re-formulated in terms of the Singular Value…

High Energy Physics - Phenomenology · Physics 2008-11-26 Andreas Hoecker , Vakhtang Kartvelishvili

Optical coherence tomography (OCT) is a prevalent non-invasive imaging method which provides high resolution volumetric visualization of retina. However, its inherent defect, the speckle noise, can seriously deteriorate the tissue…

Computer Vision and Pattern Recognition · Computer Science 2022-01-31 Dewei Hu , Yuankai K. Tao , Ipek Oguz

Recent RGB-guided depth super-resolution methods have achieved impressive performance under the assumption of fixed and known degradation (e.g., bicubic downsampling). However, in real-world scenarios, captured depth data often suffer from…

Computer Vision and Pattern Recognition · Computer Science 2025-03-20 Zhengxue Wang , Zhiqiang Yan , Jinshan Pan , Guangwei Gao , Kai Zhang , Jian Yang

Inverse problems generally require a regularizer or prior for a good solution. A recent trend is to train a convolutional net to denoise images, and use this net as a prior when solving the inverse problem. Several proposals depend on a…

Computer Vision and Pattern Recognition · Computer Science 2023-07-12 Kyle Luther , H. Sebastian Seung

Proper regularization is crucial in inverse problems to achieve high-quality reconstruction, even with an ill-conditioned measurement system. This is particularly true for three-dimensional photoacoustic tomography, which is computationally…

Optimization and Control · Mathematics 2024-09-26 Chao Wang , Alexandre H. Thiery