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We explore the potential application of quantum annealing to address the protein structure problem. To this end, we compare several proposed ab initio protein folding models for quantum computers and analyze their scaling and performance…

Quantum Physics · Physics 2026-04-27 Timon Scheiber , Matthias Heller , Andreas Giebel

We present an algorithm to solve a system of diagonal polynomial equations over finite fields when the number of variables is greater than some fixed polynomial of the number of equations whose degree depends only on the degree of the…

Computational Complexity · Computer Science 2016-06-09 Gabor Ivanyos , Miklos Santha

Systems of linear equations are used to model a wide array of problems in all fields of science and engineering. Recently, it has been shown that quantum computers could solve linear systems exponentially faster than classical computers,…

Nonlinear equations are challenging to solve due to their inherently nonlinear nature. As analytical solutions typically do not exist, numerical methods have been developed to tackle their solutions. In this article, we give a quantum…

Quantum Physics · Physics 2025-11-04 Nhat A. Nghiem , Tzu-Chieh Wei

I present a novel use of quantum annealing to solve the Set Splitting Problem using (QUBO) problem formulation. The contribution of the work is in formulating penalty functions that ensure the ground state of the QUBO Hamiltonian…

Quantum Physics · Physics 2025-08-11 Sean Borneman

We propose a framework to solve non-linear and history-dependent mechanical problems based on a hybrid classical computer -- quantum annealer approach. Quantum Computers are anticipated to solve particular operations exponentially faster.…

Computational Engineering, Finance, and Science · Computer Science 2024-02-20 Van-Dung Nguyen , Ling Wu , Françoise Remacle , Ludovic Noels

We use exact enumeration to characterize the solutions of quadratic unconstrained binary optimization problems of less than 21 variables in terms of their distributions of Hamming distances to close-by solutions. We also perform experiments…

Quantum Physics · Physics 2025-11-04 Vrinda Mehta , Fengping Jin , Kristel Michielsen , Hans De Raedt

Identifying computational tasks suitable for (future) quantum computers is an active field of research. Here we explore utilizing quantum computers for the purpose of solving differential equations. We consider two approaches: (i) basis…

Quantum Physics · Physics 2021-07-14 Benjamin Zanger , Christian B. Mendl , Martin Schulz , Martin Schreiber

Quantum annealing is a heuristic quantum optimization algorithm that can be used to solve combinatorial optimization problems. In recent years, advances in quantum technologies have enabled the development of small- and intermediate-scale…

Quantum Physics · Physics 2022-10-05 Sheir Yarkoni , Elena Raponi , Thomas Bäck , Sebastian Schmitt

We solve the one-dimensional Helmholtz equation in several scenarios using the quantum annealer provided by the D-Wave systems within a pseudospectral scheme, where its solution is encoded into certain set of suitable basis functions. We…

Quantum Physics · Physics 2025-07-21 Aigerim Bazarkhanova , Alejandro J. Castro , Antonio A. Valido

Quantum annealing has the potential to find low energy solutions of NP-hard problems that can be expressed as quadratic unconstrained binary optimization problems. However, the hardware of the quantum annealer manufactured by D-Wave…

Quantum Physics · Physics 2024-01-22 Elijah Pelofske , Georg Hahn , Hristo N. Djidjev

Quantum annealing (QA) is a promising approach for not only solving combinatorial optimization problems but also simulating quantum many-body systems such as those in condensed matter physics. However, non-adiabatic transitions constitute a…

Quantum Physics · Physics 2022-09-21 Takashi Imoto , Yuya Seki , Yuichiro Matsuzaki

Although quantum computing hardware has evolved significantly in recent years, spurred by increasing industrial and government interest, the size limitation of current generation quantum computers remains an obstacle when applying these…

Quantum Physics · Physics 2020-01-20 Gideon Bass , Max Henderson , Joshua Heath , Joseph Dulny

Quantum Annealing (QA) can efficiently solve combinatorial optimization problems whose objective functions are represented by Quadratic Unconstrained Binary Optimization (QUBO) formulations. For broader applicability of QA, quadratization…

Quantum Physics · Physics 2025-07-29 Hyakka Nakada , Shu Tanaka

Quantum annealers provide an effective framework for solving large-scale combinatorial optimization problems. This work presents a novel methodology for training Variational Quantum Algorithms (VQAs) by reformulating the parameter…

Quantum Physics · Physics 2025-09-03 Ernesto Acosta , Guillermo Botella , Carlos Cano

The focus of this work is to explore the use of quantum annealing solvers for the problem of phase unwrapping of synthetic aperture radar (SAR) images. Although solutions to this problem exist based on network programming, these techniques…

Computer Vision and Pattern Recognition · Computer Science 2020-10-02 Khaled A. Helal Kelany , Nikitas Dimopoulos , Clemens P. J. Adolphs , Bardia Barabadi , Amirali Baniasadi

The graph isomorphism problem remains a fundamental challenge in computer science, driving the search for efficient decision algorithms. Due to its ambiguous computational complexity, heuristic approaches such as simulated annealing are…

Quantum Physics · Physics 2025-05-06 Yukun Wang , Yingtong Shen , Zhichao Zhang , Linchun Wan

We propose an efficient algorithm that combines column generation and quantum annealing to solve binary quadratic problems. Binary quadratic problems are difficult to solve because they are NP-hard. An attempt to solve binary quadratic…

Disordered Systems and Neural Networks · Physics 2023-10-24 Sota Hirama , Masayuki Ohzeki

Recent advances bring within reach the viability of solving combinatorial problems using a quantum annealing algorithm implemented on a purpose-built platform that exploits quantum properties. However, the question of how to tune the…

Data Structures and Algorithms · Computer Science 2014-10-21 Andrew D. King , Catherine C. McGeoch

Quantum annealing provides a promising route for the development of quantum optimization devices, but the usefulness of such devices will be limited in part by the range of implementable problems as dictated by hardware constraints. To…

Quantum Physics · Physics 2015-10-14 Walter Vinci , Tameem Albash , Gerardo Paz-Silva , Itay Hen , Daniel A. Lidar