Related papers: Invariant in variants
Pathogens drive changes in host immune systems that in turn exert pressure for pathogens to evolve. Quantifying and understanding this constant coevolutionary process has clear practical global health implications. Yet its relatively easier…
The COVID-19 pandemic has magnified an already existing trend of people looking for healthcare solutions online. One class of solutions are symptom checkers, which have become very popular in the context of COVID-19. Traditional symptom…
The COVID-19 pandemic is accompanied by a massive "infodemic" that makes it hard to identify concise and credible information for COVID-19-related questions, like incubation time, infection rates, or the effectiveness of vaccines. As a…
The new coronavirus 2019 (COVID-2019) has rapidly become a pandemic and has had a devastating effect on both everyday life, public health and the global economy. It is critical to detect positive cases as early as possible to prevent the…
The virus SARS-COV-2 caused disease COVID-19 has been declared a pandemic by WHO. Currently, over 210 countries and territories have been affected. Careful, well-designed drugs and vaccine for the total elimination of this virus seem to be…
The rapid evolution and global impact of coronaviruses, notably SARS-CoV-1 and SARS-CoV-2, underscore the importance of understanding their molecular mechanisms in detail. This study focuses on the receptor-binding motif (RBM) within the…
Coronavirus COVID-19 spreads through the population mostly based on social contact. To gauge the potential for widespread contagion, to cope with associated uncertainty and to inform its mitigation, more accurate and robust modelling is…
The ongoing Coronavirus disease 2019 (COVID-19) is a major crisis that has significantly affected the healthcare sector and global economies, which made it the main subject of various fields in scientific and technical research. To properly…
Vortex-dominated flows are ubiquitous in engineering, and the ability to efficiently manipulate the dynamics of these vortices has broad applications, from wake shaping to mixing enhancement. However, the strongly nonlinear behavior of the…
Standard practice attempts to remove coordinate influence in physics through the use of invariant equations. Trans-coordinate physics proceeds differently by not introducing space-time coordinates in the first place. Differentials taken…
Rhythm patterns can be performed with a wide variation of tempi. This presents a challenge for many music information retrieval (MIR) systems; ideally, perceptually similar rhythms should be represented and processed similarly, regardless…
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has a variable clinical presentation that ranges from asymptomatic, to severe disease with cytokine storm. The mortality rates also differ across the globe, ranging from 0.5-13%.…
The recent outbreak of the novel coronavirus is wreaking havoc on the world and researchers are struggling to effectively combat it. One reason why the fight is difficult is due to the lack of information and knowledge. In this work, we…
Proteins are key building blocks of virtually all life, providing the material foundation of spider silk, cells, and hair, but also offering other functions from enzymes to drugs, and pathogens like viruses. Based on a nanomechanical…
New COVID-19 epidemic strains like Delta and Omicron with increased transmissibility and pathogenicity emerge and spread across the whole world rapidly while causing high mortality during the pandemic period. Early prediction of possible…
The COVID-19 pandemic response relied heavily on statistical and machine learning models to predict key outcomes such as case prevalence and fatality rates. These predictions were instrumental in enabling timely public health interventions…
Seasonal variation in environmental variables, and in rates of contact among individuals, are fundamental drivers of infectious disease dynamics. Unlike most periodically-forced physical systems, for which the precise pattern of forcing is…
The COVID-19 pandemic is one of the most challenging healthcare crises during the 21st century. As the virus continues to spread on a global scale, the majority of efforts have been on the development of vaccines and the mass immunization…
Phase invariants are important pieces of information about the atomic structures of crystals. There are several mathematical methods in X-ray crystallography to estimate phase invariants. The multi-wave diffraction phenomenon offers a…
As the major target of many vaccines and neutralizing antibodies against SARS-CoV-2, the spike (S) protein is observed to mutate over time. In this paper, we present statistical approaches to tackle some challenges associated with the…