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Sickle cell disease (SCD) is a major public health priority throughout much of the world, affecting millions of people. In many regions, particularly those in resource-limited settings, SCD is not consistently diagnosed. In Africa, where…

Sickle cell anemia, which is characterized by abnormal erythrocyte morphology, can be detected using microscopic images. Computational techniques in medicine enhance the diagnosis and treatment efficiency. However, many computational…

Computer Vision and Pattern Recognition · Computer Science 2024-12-25 Victor Júnio Alcântara Cardoso , Rodrigo Moreira , João Fernando Mari , Larissa Ferreira Rodrigues Moreira

Sickle cell disease (SCD) remains a critical global health issue, with high child mortality in low-resource regions. Early screening and diagnosis is essential for improving health outcomes, but conventional screening methods are unsuitable…

Medical Physics · Physics 2025-10-06 Nakul Sridhar , Meiou Song , Michael H. B. Stowell , Kathryn L. Hassell , Xiaoyun Ding

In this work we propose an approach to select the classification method and features, based on the state-of-the-art, with best performance for diagnostic support through peripheral blood smear images of red blood cells. In our case we used…

Machine Learning · Computer Science 2020-10-12 Nataša Petrović , Gabriel Moyà-Alcover , Antoni Jaume-i-Capó , Manuel González-Hidalgo

We introduce a machine learning-based method for fully automated diagnosis of sickle cell disease of poor-quality unstained images of a mobile microscope. Our method is capable of distinguishing between diseased, trait (carrier), and normal…

Computer Vision and Pattern Recognition · Computer Science 2021-03-31 Sahar A. Nasser , Debjani Paul , Suyash P. Awate

Identification of abnormalities in red blood cells (RBC) is key to diagnosing a range of medical conditions from anaemia to liver disease. Currently this is done manually, a time-consuming and subjective process. This paper presents an…

Computer Vision and Pattern Recognition · Computer Science 2021-06-02 Annika Wong , Nantheera Anantrasirichai , Thanarat H. Chalidabhongse , Duangdao Palasuwan , Attakorn Palasuwan , David Bull

Sickle Cell Disease (SCD) is a hereditary disorder of red blood cells in humans. Complications such as pain, stroke, and organ failure occur in SCD as malformed, sickled red blood cells passing through small blood vessels get trapped.…

Acute Myeloid Leukemia (AML) is a highly aggressive blood cancer with low survival rates. Hence, emphasizing the importance of the urgent need for effective treatment modalities. In recent times, the advances in cancer genomics have…

Other Quantitative Biology · Quantitative Biology 2025-12-09 Sadia Ruhama

Cardiovascular diseases are widespread among patients with chronic noncommunicable diseases and are one of the leading causes of death, including in the working age. The article presents the relevance of the development and application of…

Machine Learning · Computer Science 2023-08-22 T. V. Afanasieva , A. P. Kuzlyakin , A. V. Komolov

Sickle cell disease (SCD) is a severe genetic hemoglobin disorder that results in premature destruction of red blood cells. Assessment of the severity of the disease is a challenging task in clinical routine since the causes of broad…

Image and Video Processing · Electrical Eng. & Systems 2021-09-14 Ario Sadafi , Asya Makhro , Leonid Livshits , Nassir Navab , Anna Bogdanova , Shadi Albarqouni , Carsten Marr

This study investigates the potential of an ambulatory device that incorporates Large Language Models (LLMs) in cadence with other specialized ML models to assess anemia severity in sickle cell patients in real time. The device would rely…

Computation and Language · Computer Science 2023-05-08 Oluwatosin Ogundare , Subuola Sofolahan

Anemia, a condition marked by insufficient levels of red blood cells or hemoglobin, remains a widespread health issue affecting millions of individuals globally. Accurate and timely diagnosis is essential for effective management and…

Automated disease diagnosis using medical image analysis relies on deep learning, often requiring large labeled datasets for supervised model training. Diseases like Acute Myeloid Leukemia (AML) pose challenges due to scarce and costly…

Computer Vision and Pattern Recognition · Computer Science 2024-08-26 Salome Kazeminia , Max Joosten , Dragan Bosnacki , Carsten Marr

Red blood cell (RBC) deformation is the consequence of several diseases, including sickle cell anemia, which causes recurring episodes of pain and severe pronounced anemia. Monitoring patients with these diseases involves the observation of…

Computer Vision and Pattern Recognition · Computer Science 2026-01-27 Wilkie Delgado-Font , Miriela Escobedo-Nicot , Manuel González-Hidalgo , Silena Herold-Garcia , Antoni Jaume-i-Capó , Arnau Mir

Sickle Cell Disease (SCD) is one of the most common genetic diseases in the world. Splenomegaly (abnormal enlargement of the spleen) is frequent among children with SCD. If left untreated, splenomegaly can be life-threatening. The current…

Image and Video Processing · Electrical Eng. & Systems 2020-09-08 Zhen Yuan , Esther Puyol-Anton , Haran Jogeesvaran , Catriona Reid , Baba Inusa , Andrew P. King

This work presents a novel approach for selecting the optimal ensemble-based classification method and features with a primarly focus on achieving generalization, based on the state-of-the-art, to provide diagnostic support for Sickle Cell…

Machine Learning · Computer Science 2026-01-21 Nataša Petrović , Gabriel Moyà-Alcover , Antoni Jaume-i-Capó , Jose Maria Buades Rubio

Sickle cell disease (SCD) is common across Sub-Saharan Africa. However, the investigation of SCD in this area has been significantly limited mainly due to the lack of research facilities and skilled personnel. Here, we present optical…

Leukemia is a hematologic cancer which develops in blood tissue and triggers rapid production of immature and abnormal shaped white blood cells. Based on statistics it is found that the leukemia is one of the leading causes of death in men…

Computer Vision and Pattern Recognition · Computer Science 2018-03-28 Sachin Kumar , Sumita Mishra , Pallavi Asthana , Pragya

Autistic Spectrum Disorder (ASD) is a neurological disease characterized by difficulties with social interaction, communication, and repetitive activities. While its primary origin lies in genetics, early detection is crucial, and…

Machine Learning · Computer Science 2023-12-29 Rownak Ara Rasul , Promy Saha , Diponkor Bala , S M Rakib Ul Karim , Md. Ibrahim Abdullah , Bishwajit Saha

Pain in sickle cell disease (SCD) is often associated with increased morbidity, mortality, and high healthcare costs. The standard method for predicting the absence, presence, and intensity of pain has long been self-report. However,…

Computers and Society · Computer Science 2025-11-21 Swati Padhee , Amanuel Alambo , Tanvi Banerjee , Arvind Subramaniam , Daniel M. Abrams , Gary K. Nave , Nirmish Shah
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