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Phylogenetic networks are used to display the relationship of different species whose evolution is not treelike, which is the case, for instance, in the presence of hybridization events or horizontal gene transfers. Tree inference methods…

Populations and Evolution · Quantitative Biology 2014-05-02 Mareike Fischer , Leo van Iersel , Steven Kelk , Celine Scornavacca

Understanding the evolution of a set of genes or species is a fundamental problem in evolutionary biology. The problem we study here takes as input a set of trees describing {possibly discordant} evolutionary scenarios for a given set of…

Data Structures and Algorithms · Computer Science 2019-07-10 Cedric Chauve , Mark Jones , Manuel Lafond , Céline Scornavacca , Mathias Weller

In this article we prove that the distance $d_{\mathrm{MP}}(T_1,T_2) = k$ between two unrooted binary phylogenetic trees $T_1, T_2$ on the same set of taxa can be defined by a character that is convex on one of $T_1, T_2$ and which has at…

Populations and Evolution · Quantitative Biology 2025-11-19 Mareike Fischer , Steven Kelk , Sofia Vazquez Alferez

Phylogenetic trees are a central tool in understanding evolution. They are typically inferred from sequence data, and capture evolutionary relationships through time. It is essential to be able to compare trees from different data sources…

Populations and Evolution · Quantitative Biology 2017-10-31 Michelle Kendall , Caroline Colijn

Finding the most parsimonious tree inside a phylogenetic network with respect to a given character is an NP-hard combinatorial optimization problem that for many network topologies is essentially inapproximable. In contrast, if the network…

Populations and Evolution · Quantitative Biology 2025-01-14 Martin Frohn , Steven Kelk

Maximum parsimony distance is a measure used to quantify the dissimilarity of two unrooted phylogenetic trees. It is NP-hard to compute, and very few positive algorithmic results are known due to its complex combinatorial structure. Here we…

Data Structures and Algorithms · Computer Science 2020-04-07 Mark Jones , Steven Kelk , Leen Stougie

The maximum common subtree isomorphism problem asks for the largest possible isomorphism between subtrees of two given input trees. This problem is a natural restriction of the maximum common subgraph problem, which is ${\sf NP}$-hard in…

Data Structures and Algorithms · Computer Science 2016-08-23 Andre Droschinsky , Nils M. Kriege , Petra Mutzel

The metric space of phylogenetic trees defined by Billera, Holmes, and Vogtmann, which we refer to as BHV space, provides a natural geometric setting for describing collections of trees on the same set of taxa. However, it is sometimes…

Populations and Evolution · Quantitative Biology 2018-07-12 Gillian Grindstaff , Megan Owen

Phylogenetic trees summarize evolutionary relationships between organisms, and tools to analyze collections of phylogenetic trees enable contrasts between different genes' ancestry. The BHV metric space has enabled the analysis of…

Quantitative Methods · Quantitative Biology 2026-04-24 Maria Alejandra Valdez Cabrera , Amy D Willis

The supertree problem asking for a tree displaying a set of consistent input trees has been largely considered for the reconstruction of species trees. Here, we rather explore this framework for the sake of reconstructing a gene tree from a…

Data Structures and Algorithms · Computer Science 2016-10-25 Manuel Lafond , Cédric Chauve , Nadia El-Mabrouk , Aïda Ouangraoua

We consider the numerical taxonomy problem of fitting a positive distance function ${D:{S\choose 2}\rightarrow \mathbb R_{>0}}$ by a tree metric. We want a tree $T$ with positive edge weights and including $S$ among the vertices so that…

Data Structures and Algorithms · Computer Science 2022-03-14 Vincent Cohen-Addad , Debarati Das , Evangelos Kipouridis , Nikos Parotsidis , Mikkel Thorup

Convolution trees, loopy belief propagation, and fast numerical p-convolution are combined for the first time to efficiently solve networks with several additive constraints between random variables. An implementation of this "convolution…

Computation · Statistics 2017-08-23 Oliver Serang

The Maximum Agreement Forest (Maf) problem is a well-studied problem in evolutionary biology, which asks for a largest common subforest of a given collection of phylogenetic trees with identical leaf label-set. However, the previous work…

Data Structures and Algorithms · Computer Science 2014-11-04 Feng Shi , Jianer Chen , Qilong Feng , Xiaojun Ding , Jianxin Wang

Phylogenetic networks are a type of directed acyclic graph that represent how a set $X$ of present-day species are descended from a common ancestor by processes of speciation and reticulate evolution. In the absence of reticulate evolution,…

Combinatorics · Mathematics 2017-08-11 Andrew Francis , Charles Semple , Mike Steel

Binary phylogenetic trees inferred from biological data are central to understanding the shared history among evolutionary units. However, inferring the placement of latent nodes in a tree is computationally expensive. State-of-the-art…

Populations and Evolution · Quantitative Biology 2025-03-26 Matthew J Penn , Neil Scheidwasser , Mark P Khurana , David A Duchêne , Christl A Donnelly , Samir Bhatt

Tackling simulation optimization problems with non-convex objective functions remains a fundamental challenge in operations research. In this paper, we propose a class of random search algorithms, called Regular Tree Search, which…

Optimization and Control · Mathematics 2025-06-24 Du-Yi Wang , Guo Liang , Guangwu Liu , Kun Zhang

Evolutionary relationships between species are usually inferred through phylogenetic analysis, which provides phylogenetic trees computed from allelic profiles built by sequencing specific regions of the sequences and abstracting them to…

Data Structures and Algorithms · Computer Science 2021-01-01 Luana Silva

The forest matrix plays a crucial role in network science, opinion dynamics, and machine learning, offering deep insights into the structure of and dynamics on networks. In this paper, we study the problem of querying entries of the forest…

Social and Information Networks · Computer Science 2024-09-10 Haoxin Sun , Xiaotian Zhou , Zhongzhi Zhang

Phylogenetic trees are leaf-labelled trees, where the leaves correspond to extant species (taxa), and the internal vertices represent ancestral species. The evolutionary history of a set of species can be explained by more than one…

Data Structures and Algorithms · Computer Science 2016-09-07 Asish Mukhopadhyay , Puspal Bhabak

Applying a method to reconstruct a phylogenetic tree from random data provides a way to detect whether that method has an inherent bias towards certain tree `shapes'. For maximum parsimony, applied to a sequence of random 2-state data, each…

Populations and Evolution · Quantitative Biology 2014-06-03 Mareike Fischer , Michelle Galla , Lina Herbst , Mike Steel