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Medical images are usually collected from multiple domains, leading to domain shifts that impair the performance of medical image segmentation models. Domain Generalization (DG) aims to address this issue by training a robust model with…

Image and Video Processing · Electrical Eng. & Systems 2025-06-13 Xi Chen , Zhiqiang Shen , Peng Cao , Jinzhu Yang , Osmar R. Zaiane

For medical image analysis, segmentation models trained on one or several domains lack generalization ability to unseen domains due to discrepancies between different data acquisition policies. We argue that the degeneration in segmentation…

Computer Vision and Pattern Recognition · Computer Science 2022-08-09 Ziqi Zhou , Lei Qi , Yinghuan Shi

Large-scale labeled training datasets have enabled deep neural networks to excel across a wide range of benchmark vision tasks. However, in many applications, it is prohibitively expensive and time-consuming to obtain large quantities of…

Computer Vision and Pattern Recognition · Computer Science 2020-09-22 Sicheng Zhao , Xiangyu Yue , Shanghang Zhang , Bo Li , Han Zhao , Bichen Wu , Ravi Krishna , Joseph E. Gonzalez , Alberto L. Sangiovanni-Vincentelli , Sanjit A. Seshia , Kurt Keutzer

Deep learning-based models in medical imaging often struggle to generalize effectively to new scans due to data heterogeneity arising from differences in hardware, acquisition parameters, population, and artifacts. This limitation presents…

Image and Video Processing · Electrical Eng. & Systems 2023-08-09 Sebastian Nørgaard Llambias , Mads Nielsen , Mostafa Mehdipour Ghazi

Deep Learning has thrived on the emergence of biomedical big data. However, medical datasets acquired at different institutions have inherent bias caused by various confounding factors such as operation policies, machine protocols,…

Image and Video Processing · Electrical Eng. & Systems 2019-11-15 Yundong Zhang , Hang Wu , Huiye Liu , Li Tong , May D Wang

Deep learning (DL)-based models have demonstrated good performance in medical image segmentation. However, the models trained on a known dataset often fail when performed on an unseen dataset collected from different centers, vendors and…

Computer Vision and Pattern Recognition · Computer Science 2020-09-04 Lei Li , Veronika A. Zimmer , Wangbin Ding , Fuping Wu , Liqin Huang , Julia A. Schnabel , Xiahai Zhuang

Image alignment across domains has recently become one of the realistic and popular topics in the research community. In this problem, a deep learning-based image alignment method is usually trained on an available largescale database.…

Computer Vision and Pattern Recognition · Computer Science 2019-06-03 Thanh-Dat Truong , Khoa Luu , Chi Nhan Duong , Ngan Le , Minh-Triet Tran

Though convolutional neural networks (CNNs) have demonstrated remarkable ability in learning discriminative features, they often generalize poorly to unseen domains. Domain generalization aims to address this problem by learning from a set…

Computer Vision and Pattern Recognition · Computer Science 2021-04-06 Kaiyang Zhou , Yongxin Yang , Yu Qiao , Tao Xiang

Accurate medical image segmentation is essential for effective diagnosis and treatment planning but is often challenged by domain shifts caused by variations in imaging devices, acquisition conditions, and patient-specific attributes.…

Image and Video Processing · Electrical Eng. & Systems 2024-12-06 Jie Bao , Zhixin Zhou , Wen Jung Li , Rui Luo

Domain generalization (DG) task aims to learn a robust model from source domains that could handle the out-of-distribution (OOD) issue. In order to improve the generalization ability of the model in unseen domains, increasing the diversity…

Computer Vision and Pattern Recognition · Computer Science 2024-09-10 Shanshan Wang , ALuSi , Xun Yang , Ke Xu , Huibin Tan , Xingyi Zhang

We strive to learn a model from a set of source domains that generalizes well to unseen target domains. The main challenge in such a domain generalization scenario is the unavailability of any target domain data during training, resulting…

Machine Learning · Computer Science 2022-02-17 Zehao Xiao , Xiantong Zhen , Ling Shao , Cees G. M. Snoek

Domain shift is a significant problem in histopathology. There can be large differences in data characteristics of whole-slide images between medical centers and scanners, making generalization of deep learning to unseen data difficult. To…

Computer Vision and Pattern Recognition · Computer Science 2019-09-27 Karin Stacke , Gabriel Eilertsen , Jonas Unger , Claes Lundström

Magnetic resonance (MR) imaging, including cardiac MR, is prone to domain shift due to variations in imaging devices and acquisition protocols. This challenge limits the deployment of trained AI models in real-world scenarios, where…

Computer Vision and Pattern Recognition · Computer Science 2025-08-11 Xin Ci Wong , Duygu Sarikaya , Kieran Zucker , Marc De Kamps , Nishant Ravikumar

Single-source Domain Generalized Object Detection (SDGOD), as a cutting-edge research topic in computer vision, aims to enhance model generalization capability in unseen target domains through single-source domain training. Current…

Computer Vision and Pattern Recognition · Computer Science 2025-10-23 Chen Li , Huiying Xu , Changxin Gao , Zeyu Wang , Yun Liu , Xinzhong Zhu

Machine learning techniques used in computer-aided medical image analysis usually suffer from the domain shift problem caused by different distributions between source/reference data and target data. As a promising solution, domain…

Computer Vision and Pattern Recognition · Computer Science 2021-10-26 Hao Guan , Mingxia Liu

Domain generalization methods aim to learn models robust to domain shift with data from a limited number of source domains and without access to target domain samples during training. Popular domain alignment methods for domain…

Machine Learning · Computer Science 2022-06-17 Wenyu Zhang , Mohamed Ragab , Chuan-Sheng Foo

Single source domain generalization (SDG) holds promise for more reliable and consistent image segmentation across real-world clinical settings particularly in the medical domain, where data privacy and acquisition cost constraints often…

Computer Vision and Pattern Recognition · Computer Science 2024-04-04 Shahina Kunhimon , Muzammal Naseer , Salman Khan , Fahad Shahbaz Khan

Supervised deep learning usually faces more challenges in medical images than in natural images. Since annotations in medical images require the expertise of doctors and are more time-consuming and expensive. Thus, some researchers turn to…

Computer Vision and Pattern Recognition · Computer Science 2025-02-25 Tao Yang , Lisheng Wang

Medical imaging models frequently fail when deployed across hospitals, scanners, populations, or imaging protocols due to domain shift, limiting their clinical reliability. While transfer learning and domain adaptation address such shifts…

Computer Vision and Pattern Recognition · Computer Science 2026-03-26 Mohammed M. Abdelsamea , Daniel Tweneboah Anyimadu , Tasneem Selim , Saif Alzubi , Lei Zhang , Ahmed Karam Eldaly , Xujiong Ye

Domain shift refers to the well known problem that a model trained in one source domain performs poorly when applied to a target domain with different statistics. {Domain Generalization} (DG) techniques attempt to alleviate this issue by…

Machine Learning · Computer Science 2017-10-11 Da Li , Yongxin Yang , Yi-Zhe Song , Timothy M. Hospedales